Member Info for horse1

Bang on mate, let’s look forward to the coming weeks and months and I really hope everyone’s target is at least met or hopefully surpassed. GLA LTH’s and VLTH’s, oh, any any other holders.

I remember lots of people from back then, like me most do not post very often. You lads probably missed the 3.8p spike in 2011, I did, I was convinced it was going to fly after the 10/10 mice results. I do think though that our time will come this year. My target is 20p, if it reaches that I will be gone. Good to hear from some fellow sufferers lol. GLA

I keep reading this term ‘Long term holders’ LTH’s. How long to you have to have held these to be a classed as a LTH? I have held these for 12 years non stop, does that qualify? I am doing possibly one the few on here who is a VLTH. Good luck All.

The more I read the new agreement made with Sierra last year, the more I think there will be further negotiations. Sierra will know the potential of SRA737 and the reason for stalling, IMHO, is they want it all to themselves, it just does not make any sense to hold back on what is potentially a blockbuster. Sierra, and all of us, know that there is still a high chance of failure at this stage of the development and this will be the bargaining discussion.
With the royalties being 10% ( high single digit low double digit) that would be £bns a year for the life of the drug. Sierra will not have the cash to take SRA737 all the way so the big boys will, and they will want it all for themselves.
With out share of the new agreed milestones being now around £75 million what would it cost to take full ownership? Obviously the biggest cost would be paying off the Cancer Pioneering Fund who have 73% of the milestone payments, roughly £210 million.
We have all seen the figures for compounds, not as promising as SRA737, and they are eye watering. So with the failure rate setting the agenda, Sareum looking for cash and the CPF looking for treatments what figure for complete ownership.
IMHO that is why there is silence around SRA737, not even mentioned in presentations. Just out of interest, with the reasoning mentioned above I would say a figure of £500m would seal the deal with Sareum getting their 27%. Interestingly the biggest drop in the milestone payments is the dosing of the 1st patient, dropping from £12 million to £2 million, again in IMHO this is very close to happening.

Interesting sub subject in the last link you posted. Covid 19 and lung cancer have common pathway.
GLA.
https://www.news-medical.net/news/20210219/COVID-19-and-lung-cancer-have-a-common-pathway-say-researchers.aspx

Apologies for the poor grammar.
More confident that news from Sierra will be with us sooner rather than later. GLA

Great post. Reading that list of requirements make be much more confident of news from Sierra will be with us in the very near future. During the recent renegotiations this list must have been on the menu for discussion. GLA.

Hello Bythesea, I posted this a few weeks back. Hopefully it will help you a little.

When any company floats on any stock exchange, they have to set a nominal or par value, normally this is a very low price, typically 1p. This nominal value has no effect on the actual market price. So when this proposal is in place you can sell all of your holdings, if you wish, for the market value on that day. So if you hold 2000 shares now and you sold then for say 9p today, after this proposal you can still sell your 2000 shares for the market value on that day, which may be higher, lower or the same as todays price.
The reason they have made this change, is because years ago when shares were issued they set the par price at 10p, with todays price below this price, they cannot issue more shares (raise funds) at a higher price than the par/nominal price. If you look at most shares on AIM, there shares will have a nominal value of 1p.
Your right to sell all of your holding at the market price on that day is still available to you. GLA

Great analogy. A new chair, blazer and headphones, could signal retirement preparation.
GLA

Some great replies there, thank you. I suppose if we get a options RNS soon that would be very encouraging, like most of us on here agree, they will deserve a big reward if we get the share price we think we deserve. Thanks again and GLA.

Just a point on the board members share holdings/options (From chart above). I understand that most of the board are having a % of their salaries paid in shares options but, apart from Tim and John, the rest do not seem to be holding that many.
Steven Parker around 4 Million
Clive Birch 2 Million
Michael Owen only 550,000.
I would have thought, that if not in a closed period, they would have filled their boots with so much news pending. Michael Owen with only 550,000 would only get 55K if the share price ever hit 10p.
I know it has been mentioned on here before but if there was some buying, when allowed, by the board members this would show some real confidence. Maybe they are expecting 20p + which would make them all at least millionaires.
GLA

Yes I understand that, lol. GLA

in one's back pocket
1.(idiomatic) Available to use as a resource for one's advantage whenever needed; in reserve.
Whenever needed? GLA

Agree Bridges, how the hell did he get his license back?? GLA

Interesting that the man who could once do no wrong, is starting a new investment company concentrating on Biotechs. GLA
https://www.theguardian.com/business/2021/feb/14/investment-manager-neil-woodford-to-set-up-new-fund

When any company floats on any stock exchange, they have to set a nominal or par value, normally this is a very low price, typically 1p. This nominal value has no effect on the actual market price. So when this proposal is in place you can sell all of your holdings, if you wish, for the market value on that day. So if you hold 2000 shares now and you sold then for say 9p today, after this proposal you can still sell your 2000 shares for the market value on that day, which may be higher, lower or the same as todays price.
The reason they have made this change, is because years ago when shares were issued they set the par price at 10p, with todays price below this price, they cannot issue more shares (raise funds) at a higher price than the nominal price. If you look at most shares on AIM, there shares will have a nominal value of 1p.
Your right to sell all of your holding at the market price on that day is still available to you. GLA

I mentioned a while back that I thought there would be 300m shares in GCM by the time we get this project to fly. Tang has always been keen to keep the maximum level of anyone’s holding below 30%. Today’s RNS cleared the way for a placing below 10p. It depends how much he thinks he needs and how long he thinks this will drag on. I would suggest the next placing news will be 50million shares at around 5/6p this will raise £2.5/3 million.
The other thing to note is that as the total number of shares increases the existing % of ownership falls so the likes of Polo and Dyani have more scope to increase there number of shares, staying below 30%. GLA

Not sure if this has been mentioned before, but the Dr who carried out the lupus experiment with the SAR compound with SRI, Dr. Abhishek Trigunaute, was mentored by Dr Paul Stein. Dr Paul Stein is now a Director of Moderna, the Co that developed the Covid vaccine.
Dr Stein will know all about the Sareum compounds. GLA

Covid has claimed over 100,000 lives now. At this evenings briefing, Sir Simon Stevens, again, mentioned new treatments arriving over the next 6-18 months. As mentioned in an earlier post, treatments seem to be getting more and more focus. GLA

https://www.tax.service.gov.uk/calculate-your-capital-gains/resident/shares/disposal-date