Member Info for hold4results

Right then, I've got my big foam pointy finger and a novelty hat that says "Make Epithelial Cells Great Again".
I hope he plays the hits.

Scinv, it doesn't have to be perfect, for now it has to be a start. Even if efficacy is only, say 30% by 6 months, it's still far better than what we have now, which is nothing. As long as there's enough safety data to satisfy regulators it's worthwhile to get going IMHO.

Moderna's results are more good news for the world. In the long term, we now have a clear route to getting the virus under control. Sadly in the short term, the next 100 days will be the worst of the pandemic so far - at least on a global scale, if not here.

Sadly we are still a long way from 'peak covid' IMHO
https://www.worldometers.info/coronavirus/

On current trends, the world will reach 1 million new cases per day long before we can vaccinate 1 million people per day. (We need vaccinations as a new stat on the dashboards!). Vaccines will take time to roll out and more time to have an impact at scale, however good they are and however many we get.

Here's the paper: https://advances.sciencemag.org/content/early/2020/11/13/sciadv.abe4724
Really seems promising.

But just in competition terms - this was not placebo controlled, I'd suggest it's some way behind us.

Fascinating: "...the scientists were able to show that barcitinib reversed ACE2 gene expression changes triggered by interferons and reduced SARS-CoV-2 infectivity. Interestingly, interferons did not have the same effect on the ACE2 receptor in lung organoids, suggesting that these signaling proteins affect pulmonary and liver organs differently."

That might explain why SNG001 is effective later in the disease than expected.
Incidentally it sounds like this drug could be complementary and combining both could be the knockout.
Merely musing aloud.

Org I feel terrible that you knew this would happen all along and we mislead you.
Let us all switch to following Trueway, who will surely lead us to the promised land.

https://www.youtube.com/watch?v=afRqVmMf1Lo

Yes but you're not JUST here to earn money, or you wouldn't be posting. :P
Buy or sell as you see fit, TBH I'd prefer you didn't keep moving these 100k chunks about as it does have an effect, esp when volumes are low.
Actually I'm curious how you do that, how come you don't have to wait for settlement?

Stop that please

He's been running this show for the last 15 years and your primary complaint is that he's getting some credit for the work?
Away with ye. Stop being wrong.

https://www.synairgen.com/about-us/synairgens-directors/

Just to kick you while you're down, he's not an accountant either, he's project management.
Now everyone shake hands

You've misread it scinv, he and others had options due to expire, the company bought them for him.
Whether you think he's worth it or not is up to you, none of us are claiming he's the messiah.
We can all read and watch what he says and does and judge for ourselves.

https://www.thelancet.com/journals/lanres/onlineFirst I think?

Ouch. Very tough few days here, it's a shame that good news for the world has meant bad news for our SP, made it a bit harder to celebrate. But it is ultimately very good news for everyone.

It caught me out. My working assumption was that the market already expected a vaccine. I guess we didn't expect it to be this effective or this quick. I'm envious of those who managed to trade out and back in and those building positions at these prices. Commiserations to those like me who feel a bit hard up with our piles of placing shares. My timing here has been unfortunate this time round. But - onwards and upwards. Grateful to Polar Capital for being our port in a storm.

I think the professionals are right to urge caution - we don't actually have the vaccine yet and there is less than 2 months of data from less than 100 patients infected. However, it does feel like a turning point and bodes well for other vaccines too. Light at the end of the tunnel - but we're still at the wrong end of the tunnel.

There are also still those who can't have it, those who won't, and those where it doesn't work. And lots of unknowns - crucially we don't know if it prevents infection or just symptoms, in which case it can't help us stop the virus spreading.

I guess there has been some panic about our prospects, but quite a lot of investors are probably just seeking easier/safer short term gains elsewhere at the moment. This is a signpost of a way out of lockdowns, getting the numbers under control, returning to economic activity etc. I can see how buying cheap bluechips is attractive. Biden's win also adds some certainty and optimism for many.

Most of us here believe in the drug and accept the risks of P3, so the important question maybe more about demand for it. SNG001 has great prospects beyond covid, but it seems very premature to discount use in covid.

Our production plan is for 100,000 treatment courses per month. We are currently at 10,000 hospitalisations per week in the UK alone. The numbers are sadly likely to get worse before they get better.

As things stand, there is global demand for effective covid treatments that is far larger than we could hope to supply and still growing exponentially, with no indication of slowing down. Sadly it's far too soon to even call the peak of the virus, let alone the end.

If P3 bears out the P2 success, I expect high demand for SNG001 for a long time to come. The current market cap could be earned in a single month of sales. We're fully funded to get there. I plan to hold for results. It did work the first time :)

Best wishes to all.

It's a 14 day course and the figure people have been using here to do estimates is £100 a dose, so £1400 for the course.
However, that's not based on anything really solid. Somewhere between £1000 and £2000 per course seems realistic to me.

I quite fancy one of those Japanese robotic ones that steam cleans and gently towels you off.
And then reminds you to eat more fibre.

Numis. They haven't made it public but some people have copied bits over.

https://www.youtube.com/watch?v=qz2bOXLEvuE

Them's the rules but they're not always followed, I think we've had a few late TR1s here within the last 6 months. Obviously the company can only issue them when notified and apparently there's no real penalty for missing the deadline.

I think the job in these situations is to firmly insist you have a scooby while everyone scrambles around looking for one.
Like Churchill. Or not, as the case has been.