RE: Wellcome Trust LMIC’s + CHIM’s + ORPH = £’s14 Feb 2021 13:46
Cont....
The plan is to analyse in depth 250 x dengue patients through disease progression using hospital wearables (higher quality info because patients aren't moving around and there aren't 'signal quality/reception' issues that there are 'in the field'), then train up the 'learning algorithms' to make sense of all the data.
At the 'consumer' end, the idea would be to provide/distribute (according to budget) a range of wearables, the cheapest for passive monitoring/treatment of specific diseases ('come into hospital now')ranging up to wider scope/more predictive models for mass health monitoring purposes.
[In the UK, I think there's been some of this already , using oxygen levels as the 'prompt.
I imagine that the more predictive models - but for personal use - would be the area of interest to ORPH as data provider to fitbit/Apple, etc.
Presumably, the offering could be calibrated/priced according to 'coverage' : if I'm never going to the tropics, I don't need to monitor for tropical disease. Or I could upgrade temporarily : A bit like my mobile phone 'bolt on', maybe ?]
They'll be using some signal processing /machine learning techniques already developed by OUCRU for tetanus.
Damien touched on the difficulties of
- measuring effectiveness and 'economic value' (which might influence a Health Ministry willingness to support investment); and
- the ethical issues surrounding ownership of data.
One particular 'hot rail' topic is that apparently 'pulse oximetry' is less accurate in the BAME population, leading to unconscious 'racial bias' in the calibration of instruments,
See hxxps://www.nejm.org/doi/pdf/10.1056/NEJMc2029240?listPDF=true
The OUCRU/Imperial/Wellcome adopts a holistic approach, Damien's team include clinicians, engineers, data scientists and social scientists to progress from physiology > signals > clinicians > user.
The seminar gave me a bit of a better understanding of the practicalities and potential read-across for ORPH, I hope some of the above [ my interpretation] is of interest.
E&OE
ATB