Member Info for DRB83

So yes the 2g does detect the ORF1 and s gene also. So the difference between the 2g and the 3g is the M gene. I would have thought most PCR tests were at least 2g though so not sure what makes ours unique. Certainly 1g tests will be no good now.

COVID-19 2G. ORF 1ab and. S gene targets. Nasopharyngeal swabs, Oropharyngeal swabs and Sputum

By the way soder, more than happy with your assumptions and calculations. Let's not fall into the trap of 12 months ago. I recall seeing predictions of £20-25 by Xmas. Let's keep our feet on the ground and hope for £6-7 next week. A small build up to fair value over the next few months would be very nice indeed.

Larry, I am not sure you're entirely correct. Please check the Xmas target thread. I believe our 3g PCR test may be able to inadvertently indicate if the positive is Omicron or not by a unique characteristic of Omicron making the s gene indicator drop out. The result would need validating by something like a SNPsig but as we don't have one yet the 3g test would offer enough indication to justify asking that person and all their contacts to isolate regardless of vaccine status. Correct me if I'm wrong of course

Tell me this was included in the Genesig test that was approved on Friday

June 3 RNS

genesig® COVID-19 3G is a CE-Marked three-gene assay to detect the ORF1ab, M gene, and S gene targets of SARS-CoV-2, enabling fulfilment of certain international testing requirements, including Fit to Fly Certificate, Test to Release and US Food and Drug Administration regulations.

Gives us a significant competitive advantage under the current climate.

How many 3g PCR tests are currently approved in the UK?

Sequencing takes up to 2 weeks so we won't be relying on that to distinguish who is Omicron positive tomorrow.

My understanding is we also do a 3 gene test and have done for a while now. If Omicron is unique to the other variants in that it causes to s gene to drop out then yes I agree it would be a good indicator to suggest a PCR 3 gene test that shows the s gene dropping out would inadvertently indicate that that person is positive of Omicron and therefore any contacts with that Omicron positive person would immediately have to isolate regardless of vaccine status. All makes sense to me but I am in no way clued up on this sort of science. Other thoughts appreciated

Oh ffs.

###The agency plans to ask its advisors who should be authorized to receive the drug. The FDA and Merck agree that children won't be eligible, and molnupiravir hasn't proven effective for patients who are already hospitalized. But the agency suggested treatment may not be authorized for pregnant women, too.

The drug also didn't help patients who were "seropositive," or had antibodies against the coronavirus because of a previous infection, though the FDA appears wary of excluding that group — or vaccinated people — as a whole. Each have some risk of hospitalization or death, particularly the subsets of people more likely to develop severe disease, the agency said.###

This sounds hell of a lot less researched than the vaccine was and yet they are trying to rush it through. The effectiveness is minimal in fact the placebo actually out performed it during a larger trial. Apparently, It should only be used on people before they require hospital treatment. Who is really going to take all these risks with a extremely unresearched pill when they only have a cough and a sniffle. I'll take my chance with a placebo thanks, in fact scratch that I'll go au naturel.

Errr, no you can't. Settle that bill then we'll talk new contracts.

No Woody, the case is there whether it's reported or not. At least now it is reported we can do something to contain it. Or would you rather these cases go undetected?

All those who have been in contact with a person who tests positive for the Omicron variant will have to self-isolate regardless of whether or not they have been vaccinated.

Are we talking SNPsig here as apposed to PROmate?

Not too fond of testing though

The markets were red yesterday. A lot of people converted to cash. Where will they put that cash next week?

The gov seem worried. It's spreads rapidly. Fact. It looks completely different to the Wuhan variant which was what the vaccine was based on so very possible to evade some of the vaccine. Even if this thing turns out harmless the uncertainty of it over the next few weeks will cause all sorts of market volatility. Expectedly favourably to NCYT.

I knew it as soon as they did away with PCR at the border. Boris has brought it back.

£8 would be great but trying to manage expectations. Let's see what next week brings

Sir Digby, yes always believed PCR should be used as the green light. LFT's won't be obsolete though. Having said that if we can get our 10min PCR out to market then it's game on.

It's not been confirmed yet that LFT's can't detect Omicron. Ncyt said all of their assays can detect it so I assume the LFT can. I would therefore expect at least some others will. Need to get it approved first though, well in the UK.

The Bioinformatics team at ncyt have given the sales team a extraordinary unique selling point. Our assays cover the Omicron variant. Not heard anyone else say this. If they aren't working the weekend pushing this USP down the throats of all our customers including the NHS and new leads then DA needs to start wobbling heads. Fully expecting £100m sales to be smashed for FY21 and new contracts to be signed in FY22.

Were the government thinking that Covid had conceded, if so the Omicron just socked them in the nose and reminded everyone just how fragile the situation is. Test, test, and when you think you've tested enough, test some more.

One thing I expect in the next few weeks is a FY22 forecast that has Covid revenue way north of £50m. That will take the SP up a notch.