Member Info for DonaldTrumpsWig

ICE - 'They did say they were going to sell everything they made' To be fair they were accurate on that one, they made f @ck all and sold f @ck all

Spot on Ice and thanks for sharing JT, what a great thread and clear reminder of why we are all here.

It's very very simple Pre/Cision/AVA has the ability to prolong the lives of cancer sufferers whilst sparing them the horrendous side-effects of chemo. What an incredible Christmas present

I've been in sales longer than Simon, which sadly, marks me out as a bit of an old dinosaur, !!!

However, I would absolutely love the opportunity to go to market with what Simon will have in 'his bag' in 2024.

I'm sure people will be taking his calls, accepting his appointment requests and I'm also sure he won't be kept hanging around in reception for too long reading out-of-date magazines !!

Was just typing exactly the same thing JT. Last week was about the results of the P1a trial. This week was about the new appointment.

Connected yes, but absolutely no reason they should be announced at the same time.

Nothing to see here unless you are a time wasting, FUD spreading, merchant of doom.

I'm not normally one for conspiracy theories and MM games etc, but if a II made it known that on the back of last weeks results they wanted to invest £1.5 mio in AVCT, how would you go about harvesting over a million shares from a predominantly retail investor cohort??

A shed load of orchestrated FUD and a 15% SP drop would probably do it ??????

Interesting that the LSE 'share trades' board immediately became a sea of blue on the back of the £1.5 mio trade.

Which only confirms that AIM is populated by rainbow chasing lightweights who move money around on a whim because they think 'somebody knows something over at avacta'

I've said it before, ignore unsubstantiated SP falls and unsubstantiated SP increases and keep focussed on the science, which, after last week can only be described as incredible.

Groot - 1,334 million shares at £1.11 = just under £1.5 million quid

Viking is back in ? SP will no doubt fall ....

Cheeky top up from RichKen??

I think the recent criticism of the BOD and AS in particular has been unfair. How many of us in the hypothetical situation of being able to read Wednesdays RNS and listen to CC before the market opened would’ve predicted the ensuing SP drop? Not one of us, I would suggest.

Prior to Weds, I myself called for AS to update us on plans for the commercial strategy, however upon reflection, this would’ve been incredibly difficult.

AVCT are in a very rare almost unique position of not just developing a product, they are potentially creating a market.

Only once in a generation does a product come along that redefines the market, making everything that went before it become virtually obsolete.

The best analogy I can provide is Apple with the iPad/iPhone. Do you think Steve Jobs gave a sh 1t what shareholders thought when he and Jonny Ives were creating a new market. What happened to Blackberry, Motorola, Nokia, Erickson etc after a paradigm shift in mobile telecommunications arrived?

People calling for them to deliver sales now ?? Sales of what exactly ? A platform that is only half validated? Yes, safety and tolerability is done ✔️ but what additional value if the platform is validated with P2 efficacy data?

People saying that AS and the BOD are poor at deals? The same people were not saying that when the Heights/Launch deal was announced… or AffyXcell or Point etc. They were saying that they were brilliant deals, particularly Heights/Launch.

From the Co perspective the Heights deal could be viewed as a very shrewd move , at the time P1a was far from where it is now and a profitable DX division was probably an excellent insurance policy against potential delays in the AVA trial.

Things change in business particularly in R&D focused businesses and should we really criticise the BOD if they now think that the TX is validated to such an extent that the DX is superfluous and no longer required.

The ability to pivot and change strategy when faced with an evolving opportunity is not necessarily a weakness.

People claim that AS doesn’t know what he is doing because he lacks detailed plans and ‘waffles’? But isn’t the first law of negotiation to play your cards close to your chest and keep your plans to yourself?? Who knows. ?

Despite our collective frustration that the mythical inflection point has once again disappeared over the horizon we mustn’t lose sight of the fact that this has been an absolutely brilliant week and once again the main focus remains patience.

Don’t forget that just because the market thinks AVCT is worth £1.11 today doesn’t mean that it has the foggiest clue what it will be in 6 months time.

Have a good weekend all.

I enjoyed the part where Dr Coughlin explained how they were working on a new AVA programme to target FAP in arthritis and when AS said he wanted us to become the new Wilko's

'we are seeing clear evidence of disease stabilisation'

The RNS/Presentation has given us LTH's everything we could've hoped/wished for. It re-emphasises that this remains an incredible investment opportunity that has the potential to genuinely revolutionise cancer care. With each update the value of our shares increases even if this is not reflected in the SP.

I remain convinced that the lack of SP response is more to do with the useless market where we are listed and the general lack of awareness and understanding of the AIM investor.

Today's update will be of great interest to BP and this is where value will be properly recognised.

She's professional and typically cautious but only a complete idiot like Eggy will remain in any doubt that efficacy is being seen

STS patient will be able to receive 3X the amount of AVA6k vs std dox

She's brilliant and anyone with any remaining doubts that 'it works' is being blown out of the water by her presentation

Looks like lower doses more frequently is the preferred dosing regimen

AVA600 is exquisitely selective to FAP, Fiona Mc

I’m sure he and his family have never heard of Wetherby but they’ve just received the best Christmas present they could’ve dreamed of 👍👍 good luck to them.

Says it all 👍👍 the wait is over

"The potential of the pre|CISIONTM platform to change the way in which potent cytotoxic drugs are delivered, improving cancer patients' quality of life and treatment outcomes, is truly remarkable."