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AS always said that it was important that any trial results were peer reviewed... and there you have it in black and white a positive peer review.
I’ve always been loyal to this board and enjoyed the mix of excellent posters and irreverence.
Sadly, the war appears to have been lost and like Mufasa and the hyenas in the Lion King, all the good posters have gone and it is now a dark echo chamber for the fudsters.
They are too stupid to realise that it is self-defeating to discourage quality posters who understand the science and replace them with puerile nonsense. But sadly that appears to be what has happened.
I leave you with a link where the CEO clearly explains where we are now. You either believe him or you spend your days posting negative drivel on here.
Good luck
https://video.twimg.com/amplify_video/1778314060833939456/pl/M1QeIoetPPF9DZ0p.m3u8?tag=14&container=cmaf
I didn't really expect yesterdays RNS to shift the SP, we've had RNS's with arguably more significant progress that haven't shifted the SP either.
What we received yesterday was further confirmation of the latent value that is sitting in the pre/Cision platform.
The market isn't yet ready to acknowledge this value and probably won't until independent verification is seen in the form of a LD. For the majority of LTH's who are 'trapped' underwater, yesterday's RNS simply added significant value to the end game that we are all awaiting, a BP T/O.
50p, £1, £1.50, £2.00 is becoming increasingly irrelevant to me, we are on the cusp of something much much bigger than a couple of quid and the longer we wait, as yesterday has proved, the higher that number will become.
As has been pointed out, it is 'new ISA day' and lots of shareholders, in anticipation of positive news on Weds, are piling shares into their 24/25 ISA's.
I suspect the majority of trades will be sells with matching buys (Bed & ISA) as people transfer shares from their trading accounts into their new ISA's as opposed to 'new' money being invested hence why the SP isn't moving much on the volume.
WYN /Geeman, you seem to have this bizarre notion that a) I am responsible for the share price and b) I give a sh it what you think
I must of missed the post where you told us all that a 50p raise was incoming? Or did you just say something along the lines of 'be careful share prices can go down as well as up' and then claim brilliant insight when one of those predictions actually happened?
#DTW living rent free in WYN's head
You know what PL? I actually really like this forum I like its irreverence and the humour and the abuse. I actually enjoy baiting the morons and I also enjoy when you and others do it too, it's a form of sport.
The Telegram group by contrast is much more serious and science focussed and despite the perception here, it is not an echo chamber and contains a lot of healthy, conflicting debate.
What they want to avoid at all costs, which I support, is having to accommodate the idiots we tolerate on here. You know better than anyone how difficult it is to ignore, bin, report. Every sensible thread is hijacked which is a real shame for the handful of good posters who would no doubt, as you suggest, add further context to any questions for AS
PL - I actually thought that it might be a good idea to share the questions on here but have since reflected that it wouldn't. The reason, it would simply provide the morons with the opportunity to scrutinise/criticise and generate FUD in advance of the webinar
It's very telling that the clown in chief is the poster that has been pushing for the questions more than anyone. Perhaps his paymasters want to see them in order to get their fud strategy in place before next week. Who knows? but the more the sealion and his alter-ego geeman ask for them the less inclined I am to share.
What I can assure all genuine holders is that the questions are excellent and well researched and almost entirely centring around the science and the trial status.
If AS answers them or even the majority of them I am sure it will be very illuminating for genuine LTH's and hopefully see the SP start to recover.
That's a real inferiority complex you have there Geeman/WYN (keep forgetting same person). The phrase living rent free in your head springs to mind.
Why don't you both get off to Croatia and try not to think about LFT's
In fairness Strangy, if you register for the webinar you are invited to submit your questions to AS.
As I see it, all the Telegram group are doing is consolidating questions to avoid repetition and ensuring that valuable time isn’t wasted answering questions that have been answered before or are available to be researched in previous RNS’s.
All shareholders will be able to listen to both the questions and the answers simply by watching the webinar and/or reading the follow up slides that TP have said they will publish.
WYN - 'Too late DTW, its not your club but as you have driven me off this one, I have no choice.'
Fantastic, I'm sure the members will be enthralled to receive your essays on the LFT saga. I'm also sure they will hang onto your every word as you share your vast knowledge of charts and your trading successes. I can imagine their awe as you conclude that sometimes shares go up and sometimes they go down.
PS, my understanding is that you have to own more than 100 shares to join, so you'd better buy a few before you apply.
Saint - try 'Avacta Investor discussion group'
Geeman/Wyn - please don't join, I go there to get away from you.
Geemen, what a load of insecure, ill-informed nonsense.
You don't need a link, download Telegram, find the group and join, all you have to do is prove that you are a shareholder. And that last bit is the problem for some of the planks on here.
I am a member and find it fair balanced and populated by some very well informed and reasonable posters. The topics are the same as here but just without the aquatic mammals and loons (think JT, RAH et al but without the 3 musketeers).
Just because people like this intimidate you, try not to let your insecurities get the better of you.
Strangy, I don't see what is embarrassing or unprofessional about what the Telegram group have done. It is a group that is open to anyone on the condition they can prove they are a shareholder. That in itself is great as it weeds out some of the non-shareholding nutters we get on here.
Collectively the group have a significant holding in AVCT an they have simply asked AS if he would be open to receiving questions.
This was done to avoid duplication and asking questions that have already been addressed in previous RNS's etc. A very open and democratic process was followed where all members were asked to submit (and vet) questions.
The outcome was 10 questions that in my opinion were excellent, relevant and phrased in a way to advance all of our knowledge.
I have asked if the Telegram group mods if they have any problem with me sharing on here and when I get a response I will post.
The Telegram shareholder group have been in communication with AS and asked if he would be open to receiving a series of questions for the webinar.
He has agreed to this and a poll was taken from which 10 questions were selected and submitted. IMO the questions were excellent and comprehensively covered much of what we are all seeking to understand.
It remains to be seen how comprehensively he answers ??
Stating facts is not ramping, stating that AVA6000 has demonstrated a remarkable safety and tolerability profile is not ramping, stating that early signs of efficacy have been seen is not ramping, stating that the company has approx 2 years worth of cash is not ramping, these along with many other statements are facts, RNS'd and in the public domain available for independent scrutiny.
Saying that the company is likely to fail in future because they haven't produced a working LFT, or they will fail in future because they haven't met previous timelines, or they are likely to fail because at some point in the future they will need more money, or they will fail because they haven't yet demonstrated efficacy is nothing more than supposition and guesswork.
It is nothing more than a prediction of the future with no basis in empirical evidence and it is only right that it should be discounted as such. Similarly 'the market' has arrived at its valuation on Avacta based, not on the data, but on its assumptions of the likelihood of the science being commercialised and when that will take place. It is nothing more than a collective opinion with no basis in fact. It is clear the market doesn't rate the chances too highly currently, researched LTH's rate the chances much higher. Somebody will be right, somebody will be wrong
To use supposition and guesswork as a legitimate counter-argument to published scientific data is wrong and only done by an individual with either, a limited intellect, or a spurious agenda. Discussion and debate and counter arguments about the data is healthy and valuable.
'Debate' that centres around an opinion, around a 'what if', around a comparison with the LFT is a waste of time and is propagated only by narcissists and sealions and should be ignored, binned or reported.
Take your pick with regards to the posters on here
Ice & B2 agree with all that. I would only add that what began as a simple concept (identify a MTD to guide P2RD) became significantly more complex as P1a exceeded all expectations.
I’m sure neither the Co nor SH’s expected P1a to get to C7 without an MTD. Wether we feel that the company thereafter have been scrambling to decide the best strategy as the cohorts progress is a moot point. I think most of us would agree that they haven’t. I think most of would agree that it seems they have been struggling to decide what to do with this beast they have created.
What is clear is that the evolving trial data coupled with poor comms and an inherent lack of understanding has led to the market doing what the market always does, adopt a conservative approach until it understands the opportunity and can see a return. And when it does it will again do what it always does and pile back in very quickly..
I feel we are very close to that ‘pinch point’
Jive, I think I speak for the vast majority of posters here when I say we all value your knowledgeable and reasoned input.
Please, please don't lower yourself to engage with the two Ronnies, they will suck the life from you with sealioning nonsense. Not sure if you are already a member of the Telegram group but it is much much better than here simply because the clowns like Wyn, Derek, Thorn and Value are not present.
Lot's of robust debate around the science that you would be able to contribute to, without the thick sealion garbage that litters this board.
We all agree with you, time for a relaxing bank hol weekend and
WYN - the following quotes are taken from your posts this morning:
'So why did we go from 4 cohorts to 7 which was surprise to AVCT'
'I am reluctant to make the assumption on efficacy at this stage'
'I don't know for sure, other than clearly it has not gone to plan. Why it has not gone to plan is obviously debateable.'
You regularly ask why you are often reported for being disruptive. If you claim that you are not being disruptive then you will have to admit to bordering on being pathologically stupid if, even after all this time, you haven't understood that P1a was never designed to demonstrate efficacy and the pursuit of a MTD to guide RDP2 was the sole reason the trial extended to 7 cohorts.
Excellent post gje. Sums up the current situation perfectly.
Of course you are correct, the ‘market’ neither understands nor cares about the science. Its only interest is if it thinks it can make a quick return from its current position.
The inference that it has the inclination or aptitude to take a ‘look under the bonnet’ is laughable.
As others have pointed out AS and the BOD played a terrible game of poker. They basically let everyone around the table see their cards and surprise surprise their bluff was called and the money guys sniffed desperation and offered 50p simply because the odds of a quick return were very likely. NOT because they understood the long term opportunity of PreCision.
Gje306 - you only have to listen to that recent interview with Gervais at Premier Milton to realise that the majority of fund managers do not have an understanding of the science at AVCT.
He is a long term holder of AVCT shares and his understanding was rudimentary.