Member Info for Candid

Complete non-event. Peel Hunt picked up a majority of the recent placing shares and are now selling them onto clients on their books, Peel Hunt is a broker, this is what they do. They started with 14.57% and are now at 10.66%.

The last operational update on 24th April stated the following: (The M2 infill drilling programme has been proceeding well despite some technical and operational difficulties which has resulted in a slight delay in the completion of the eighth hole of the programme M2-040. These issues have now been resolved and the hole is expected to be completed by the end of the week. Assay samples from the earlier holes are currently being processed by Bureau Veritas in Reno, with the Company expecting to start receiving results around the end of next week.) Hence the final M2 hole was expected to be completed by 29th April. Assuming it takes at least 2-3 weeks to get assay results back, the results for the final hole on M2 won�t be in until at least the week ending 20th May You won�t get the company announcing results of earlier holes until all results are back! So for all those with no patience, please chill out, as the results will be announced once the company gets them and puts together a report of the results. GLA

What started as a relatively modest project, but now it seems all the talk is about about a big resource. These are bullets from the most recent presentation shown at Proactive: � Upside exploration potential - Vazante (Brazil) 20 Mt+ @ 18% Zn and Franklin- Sterling Hill (USA) 30 Mt+ @ 19% Zn style mineralization � 3 highly ranked drill targets nearby gravity anomalies � Current exploration results suggest significantly above previously forecasted tonnage � Zinc project has immense potential So when the company is comparing the style of mineralisation to two very big projects (Vazante and Franklin Sterling Hill) there is something to get excited about! Vazante, owned by Nexa Resources is amongst the top 10 zinc mines in the world ;)

The Glenover news is good and it sounds like genuine progress is being made. It�s not much that we didnt already know however, and is really just to announce the timeline has moved out by 2 months. What the market really wants to know are answers the following questions, particularly the 2nd one. 1. 15 years supply is mentioned but what is the size of the offtake agreement? tonnes per year? 2. How much money will the MPP offer upfront? $5m? $10m? $15m? 3. How will the floatation plant be financed? how much will it cost? 4. When will the plant be ready for production? 5. What is the expected return for Galileo and Fer-Min-Ore? 6. When will the Rare Earths be processed?

Star Zinc - results from the remaining drill holes are due, so news is likely this week. I�m expecting further high grades, ground expansion and ongoing work to fast-track the conceptual resource size estimate. Glenover - I was expecting news before 30th Apr, so there may be a delay on this. May need an extension of heads of agreement termination date if there is any slip. The mining rights might not be granted yet as the DMR don�t have a deadline, they will grant it in their own time. As Glenover was a phospate mine previously I would think it is relatively straightforward. Just an Environmental Impact Assessment was to be completed if I remember correctly. Incidently on Galileo�s website it states that they own 38% of Glenover now and the condition for the increase from 36% to 38% was a grant of the mining right, so by this fact it seems that it�s altrady in the bag. Placement - Peel Hunt It seems that Peel Hunt took most of the 50m placement shares, they certainly got a bargain. GLA

This week we could very well have news on both projects: Star Zinc and Glenover Phosphate. 1) Glenover Phosphate The off-take agreement with Major Phosphate Producer (MPP) is due for completion on or before 30th April, so could well be this week. The conditions prescedent to be met are likely wrapped up judging by the latest presentation. Incidently did anybody notice that Galileo may have inadvertently revealed the MPP!! In the presentation the company doing the testwork is named as Omnia Group (they are a $1B South African company rapidly expanding their Agri business). This would be a perfect fit and makes sense. I thought it might be Foskor group, but Onmia is a much better prospect. Incidentally Omnia is in dispute with Foskor about supply of certain raw materials and it could well be why they are looking to source other suppliers. 2) Star Zinc Drilling results on the remaining holes from the 26H diamond drilling. The project is gathering momentum and we should have a conceptual resource estimate within a couple of months. 3) Ferber not forgetting Ferber which they claim is recieving interest from the trade so could be JV on the cards. Thanks CharlieC for the presentation btw. GLA

I�m particularly drawn to the following: 1. In-licencing of the new Gene Therapy treatment for EB, this could be disease modifying, i.e not just a treatment of the symptoms, so this can be huge, bigger than AP101 2. Lojuxta sales becoming quite significant going forward and growing 3. I always thought that the phase III AP101 trials will get delayed a bit so not at all surprised, but the data from Amicus is a big bonus, anything that will increase the chances of success is good. 4. They are talking with Amicus, perhaps Amicus is keen in an interest in Amryt?? they are a $3B company btw 5. Although not mentioned but come on Amryt, get a Nasdaq listing sorted..

I would think that a Trading update before the final results (end March) can only mean one thing: Lojuxta sales are exceeding expectations. The Licence has been expanded to cover many new geographical regions over the year.

Thanks for your view Diamondstar, that makes things clearer for me. I�m quietly confident the phase 3 trials will be successful. Key will be recruitment of patients, but now with 24 recruitiment centres around the world this should be going to schedule. I read about the Smaller scale clinical trials back in 2015/16 by Schwieger-Briel which confirmed positive results and adds some further confidence: CONCLUSION: Our results indicate a potential for faster reepithelialization of wounds in patients with dystrophic EB when treated with Oleogel-S10 but larger studies are needed to confirm significance.

Diamondstar, having some pharma experience I thought that maybe you could help me with a point about pricing? I understand that AP101 Episalvan has been approved for Partial Thickness Woulds back in 2015 and now the same product is in the current phase 3 trials for EB. Assuming there is already a market for Episalvan for Partial Thickness wounds, which must have a price for the product, if we get approval and marketing rights for EB how will this be priced? One price for Partial Thickness Wounds use and another price for EB use? considering EB is classified as a rare disease I�m assuming it will attract premium pricing?

Judging by the update from a couple weeks ago, I would think that M2 drilling should be competed by now and the drill rigs are being moved into position for completion of M4 drilling (of which 60% has already been drilled in 2017) David posted a series of photos last night on Vox Markets showing base camp for M2 and Marietta. From RNS ON 16th Feb: �The current M2 infill drill programme is nearing completion and both the in house geological team and the Company's independent geological consultant, Don Strachan, have reported observations of malachite in chip samples and excellent geology�.

Great posts Diamond, and interesting comparisons with Zorblisa/Amicus. I too believe we�re all on track, the last funding and positioning of key staff all points to confidence in the trails. I know that recruiting patients for the trials can be difficult sometimes, as mentioned before, but with such a diverse and global presence for the trials, I think this should be progressing well

Kropz is really bullish on fertilizer in South Africa, bodes well for the whole industry.. http://www.miningweekly.com/article/kropz-eyeing-first-ore-through-phosphates-plant-this-year-2018-01-23

If you listen to Colins interview on Vox Markets yesterday he gives updates on all 4 projects: Star Zinc - drilling ongoing and JORC + expansion is the target, also mentions probability of other metals, interesting.. Glenover - sounds very bullish on this, says they will be developing this project and will be an announcement soon Concordia - sounds quite sheepish understandably, conceeds that its back to an underground mining focus rather than open-pit and will wait for others to explore and develop it, retains 15% stake. Ferber - says the market has not priced this in and overlooked it, he will be looking to start exploration prob mid-year All in all very upbeat as you would expect from a CEO interview, finishes saying to expect plenty of good newsflow in the next 6 months. GLA

Good to hear an update, it�s all going to schedule. This is really a restart of drilling after the winter break, 60% of M4 drilling has already been completed before the break so good progress has already been made. While M2 is a simple drill to connect the middle section and expand the existing resource.

An interim readout is expected in the first half of 2018 for the pivotal, global Phase III trial in EB. I�m expecting the shareprice to wake up soon in anticipation. The recent raise of new money �15m is particularly encouraging �In anticipation of its successful outcome and subsequent approval, this new money will contribute to funding the pre-launch costs and the expansion of our manufacturing capacity in readiness for the commercial launch of the treatment�. This in itself sends a very strong signal, the confidence in the trials is high. I�ve added more, happy to wait a few more months, but this could take-off a5 any time as these are really tightly held.

Although the drilling results will be in March, there will be progress updates in the weeks ahead (as mentioned at the investor presentation) These alone will build momentum in the share price. If you wait till early March to jump in you will probably miss the boat as share prices usually rise in anticipation. (e.g just look at CHAR over the last few weeks, it is rising well before drilling has even begun)

For all the misinformed on this board, stop guessing and doubting and just listen to the last podcast: M4 - drilling has started last year and will finish late Jan/ early Feb, followed by 4-6 weeks of assays, with an RNS in March M2 & Sharktooth - drilling is ongoing and is part of one phase - M2 started first and Sharktooth will follow as soon as weather allows, it will complete Feb/Mar, with M2 results in early April, Sharktooth results mid-April. Place your bets

I�d say 2.5p to 3p is possible, remember that the market cap is still only ~�6m currently and this year�s exploration phase is fully funded.

A rise in this type of share typically starts well in advance of expected drilling results so I would not be surprised if we get a sustained rally all through Jan, Feb and Mar.