RE: BAMS NEWS - For the Scientifically Minded17 Sep 2020 11:00
Spike - good find!
I'm not a scientist (junior architect) but I have a research background, so I had a skim read of the top article, I think it's very relevant to us. In short key highlights are:
- One of the authors is followed by Avacta on Twitter
- The BAMS Assay Avacta is developing with Adeptrix is compatible for use on most MALDI-ToF Mass Spectrometers
- The paper outlines a comprehensive, clinically validated, sample-collection-to-lab workflow for using MALDI-ToF Mass Spectrometers to screen for COVID, based on saliva samples taken at home, to demonstrate the suitability of MALDI-ToF for population-level screening
- The paper outlines problems with PCR testing and outlines how MALDI-ToF screening avoids current bottlenecks with supplies of regents and swabs, alongside inaccuracies introduced through poor sample collection
- The paper outlines how MALDI-ToF is highly suited to population-level screening for COVID, with a much lower cost per test and much faster processing time than PCR - potentially an 80%+ cost discount
- Sensitivity of nearly 100% can be achieved with MALDI-ToF testing
If you want to read the key takeaways read the 'discussion' and 'conclusion' section at the end. If I were a company making a BAMS test for use on MALDI-ToF Mass Spectrometer, I would be very happy this paper has been published!