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Its amazing the bets that have been made on these tokens, El Salvador already suffering economically bet their future on the price of bitcoin rising, instead sunk even further into the mire.

The concern in the market has to be contagion, bit of a domino effect with some UK funds holding crypto - we have seen first hand how Jupiter/Softbank were forced sellers due to other asset classes taking a wallop.
Bitcoin Hit as ‘BlockFi Considers Bankruptcy’ in Wake of FTX Collapse

https://www.barrons.com/articles/bitcoin-price-crypto-market-today-51668589509?tesla=y

Target in the US has reported softening sales weighing on (some) retail stocks.

Another bitcoin ponzi coin is teetering along with El Salvador turning to China for help.

https://www.theguardian.com/technology/2022/nov/15/china-el-salvador-economy-cryptocurrency-fall

Ulta Beauty, Inc. (ULTA)

https://finance.yahoo.com/quote/ULTA?p=ULTA

e.l.f. Beauty, Inc. (ELF)

https://finance.yahoo.com/quote/ELF?p=ELF&.tsrc=fin-srch

This update could also be a signal for hoisting the 'for sale sign', hard to tell but I cannot see any decisions similar in recent years so something has changed.

Should make the Short side feel uneasy now that there is a firm commitment to be profitable, not unreasonable after what 22 years of shareholder support.

Astra Zeneca seems like a natural partner, 30 + years experience in China could leverage Hutchmeds assets well both at home (China) and abroad.

Its possible the board have issued this update ahead of Thursday's investor presentation, gives them a little more room to say things that would have otherwise raised questions.

Internal strategy review may have prevented director share purchases...okay, that was taking it too far lol

Following the pre-G20 meeting, US is to now send a representative to China.

Headlines reflecting this new Olive branch

> Signs of thawing relations between the US and China are giving fresh hopes to investors while Beijing unveils more measures to revive economy

https://www.scmp.com/business/markets/article/3199626/hong-kong-stocks-jump-7-week-high-signs-thawing-china-us-ties-while-beijing-moves-stimulate-economy

Influence perhaps from the somewhat recent new board member Lefei Sun, General Atlantic, either way a much welcomed update at least from me.

Treat Hutchmed as a business rather than some sort of grandiose vision which has become bloated, agree with davey's comments on being spread too thin.

Reading between the lines it appears to be already underway so we may hear something fairly soon, AstraZeneca has to be in the running partnership wise.

US/China meeting moved forward ahead of G20, seems convivial.
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AstraZeneca comments following the annual CIIE

This is the fifth time for Astra-Zeneca to participate in the annual CIIE. The company's Executive Vice-President Leon Wang said the UK pharmaceutical firm has signed 45 contracts at this year's exhibition, most of which are aimed at increasing investment, deepening cooperation and boosting innovation in China.

"We are greatly encouraged by the fact that China's supply chain is still unimpeded as well as the advantages of China's manufacturing industry and the opportunities for expanding production capacity, as well as measures taken by local governments to support foreign investment," Wang said.

Bit of a gap on HK close b around 19p, waiting for NASDAQ no doubt.

US/China meeting scheduled for this weeks G20 conference

Great to have a bit of positive news flow, yes, volume on HK second highest since first listed, short covering perhaps.

Could be good timing with the Virtual Investor Conferences this Thursday.

..small pedalo with large overweight man last seen passing Southend pier

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Store chains are increasingly fearful over spiralling costs

https://www.thisismoney.co.uk/money/markets/article-11420185/M-S-plea-help-energy-bill-leaps-100m.html?ico=mol_desktop_money-newtab&molReferrerUrl=https%3A%2F%2Fwww.dailymail.co.uk%2Fmoney%2Findex.html&_ga=2.242640002.1228598918.1658515413-204869046.1621212402

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Bitcoin miner falls back in love with real money

https://www.thisismoney.co.uk/money/investing/article-11420927/CITY-WHISPERS-Bitcoin-miner-falls-love-real-money.html?ico=mol_desktop_money-newtab&molReferrerUrl=https%3A%2F%2Fwww.dailymail.co.uk%2Fmoney%2Findex.html&_ga=2.242640002.1228598918.1658515413-204869046.1621212402

There has been a good few years of bubble investing on the back of bitcoin culminating in NFT lunacy.

We could get a rotation back into fundamental investing as institutions seek to distance themselves from such events, currently the NASDAQ is going the opposite way to bitcoin.

those pedalos can get really tiring after a while...

FTX it looks like its contained so far, Softy and Blackrock already written down holdings to zero. Its frankly staggering how these supposed experts get caught up in these things, tulips' from Amsterdam..

Ten minute conversation with any tech bod highlights the inherent weakness in bitcoin, totally flawed from the start not to mentioned hideous usage of power.

Great week with some really interesting links posted, have a good one all!

Astra Zeneca had good results lifted in part by oncology revenues.

The Astra Zeneca/ORPATHYS agreement is well underway in China, AZ need a steady supply of approvals to stay ahead of the game - how attractive would Hutchmed portfolio be?

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Virtual Investor Conferences

November 17 Agenda (US Eastern Standard Time):

11:00 AM: HUTCHMED (China) Ltd (HKEX:13, NASDAQ: HCM)

https://finance.yahoo.com/news/international-companies-host-live-webcasts-233000009.html

Each to their own Jatw and yes it may go wrong, but that is set against profits banked so far - didn't you also post a while back to buying more shares higher up?

There has been some good and bad news since your purchase, but again the share price has dropped also but we now have FRESCO-2 data, huge bonus imo.

Its worth reading the Teneo report if you haven't already, not ground breaking but a more balanced perspective perhaps.

Bookmark this link, constant updates from many companies investing in China many are overseas.

http://www.chinadaily.com.cn/business/companies

After reviewing all of the available data decided to buy back shares previously sold.

Part of this decision was based on independant reports such as Teneo but also the day to day reporting of overseas companies which continue to invest and grow, Loreal is one of many examples.

L'Oreal betting on beauty products buying bonanza

http://www.chinadaily.com.cn/a/202211/10/WS636c5095a3105ca1f22751e1.html

When you read articles such as this it highlights just what an opportunity Hutchmed has in terms of addressable market, easy to get distracted with daily media noise.

FRESCO-2 meeting the end point study tipped the balance with a partnership announcement more than likely.

Lots of other points to consider many of which have been posted below by myself or others, no advice intended.

THG management absolutely nailed it when it came to the IPO, banks were greedy and have paid the price - same with fund raise, nailed it.

Perhaps it explains buyers remorse with analyst notes ..

Guess who's in FTX, I kid you not old Softy and Blackrock.

According to CNBC stakes once valued at gazzillions now worth less than a Myprotein bar..

https://www.cnbc.com/2022/11/09/binance-backs-out-of-ftx-rescue-leaving-the-crypto-exchange-on-the-brink-of-collapse.html

THG is often compared to Amazon with many similarities and attributes, their commitment to net zero was taken up well before ESG became a standard;

How this popular Jeff Bezos quote drives Amazon’s climate goals

https://www.cnbc.com/2022/10/06/how-this-popular-jeff-bezos-quote-drives-amazons-climate-goals.html

CNBC now has a separate ESG page

ESG IMPACT EVENTS

https://www.cnbc.com/esg-impact/

More market volatility as crypto junk unwinds, FTX the latest to fail.

Would have thought a non seasonal boost due to footy and colder temps.