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Its fairly obvious to me that we will recieve the COPD data first. They are unwraping the data now. The hospital trail data cannot even start to be unwraped for a number of weeks yet, COPD data will come first imo and hopefully catch people out here.
Ghia,
Richard did'nt wake up one morning and decide this .... determining the factor which has called for this ´ unplanned interim readout ´ is important , imv
Personally, it would seem make sense to me to get the results of the COPD trial out there as soon as possible if they look positive. It would again raise the profile of the company, which I am sure is on the radar of bigger fish anyway, and I would have thought it might encourage someone to start talking more seriously ahead of the results of the home trials.
Just my view.
Nolupus - Thanks I was not aware of that fact.
Ghia ,
Stastical analysis are done outside SNG so all Richard has to do is give the GO signal
Nolupus, i can see where u r coming from; and u could be right.. may be theyll announce results and also add the progress on home trials and say that they are do e with hospital trial and are going through the data etc
Miggy,
You have proved once again your closed minded state because I have always stated the same ... interferon will be of most effect if given early on ....
I don't understand your logic this morning because there is absolutely nothing negative in what I have said this morning if anything it's highly positive if you took the time to take off your BLINKERS
They only have 109 participants data in the COPD trial, which would usually take around 3 weeks to analyse and verify.
It’s all about the results of all the trials, successful results will give a nice SP. currently it’s speculation based on press articles and small snippets from SNG. There are time factors that could have an impact on the Covid trial concluding.
Your wish is accepted. Please.. you don't know your arse from your elbow when it comes to Interferons or you wouldn't be so negative on here. Early treatment with this drug will be a winner I have little doubt based on the virus suppression of interferons. Very simple really when you think it through that a drug which boosts the interferon response in people struggling to produce it will be a success and show great benefit for them. Anyways, you are filtered.:)
Nolupus - I hope you are correct on COPD results in June that would probably catch out a few COViD speculators that have jumped ship temporarily to chase gains elsewhere before returning.
I can’t see any motive to open COPD early other than that the opportunity presented itself so why not. With both trials in full swing there is probably a window of opportunity to do data analysis without delaying COVID further. 2-3weeks to analyse COPD whilst the hospital trial completes.
Miggy , please filter me because you are coming across as being more ignorant every day ...
My research into interferons has being going on for many years well before you learnt the difference between your alpha and your beta ...
Nolupus - are you reading too much into this? SP will be based on results of the trials for covid and copd so timing is unlikely to matter hugely. If copd is a fail the sp drops, if covid is a fail then same goes. I think covid results will impact the sp more than copd right now. If they release copd first I would think the results are likely to be good.
Did you change your underpants this morning Nolupus?
Stupid leading questions that no one not even SNG can answer. Although I'll have a go even though it won't change your negativity or asking negative questions so you get your desired negative answer.
The scope of the trials have changed not really in name but in procedure. Plan I believe was always to target at home patients. If you research, most interferon treatment is a lot more effective within 72 hours post infection. Their was Ebola research stating the same thing that I read ages ago. So imo SNG have started to target treatment in the home environment because it will provide quicker access and the best results for SNG001 and the patient. In order to do this they have had to set up a complete new virtual trial logistic which fair play to them they have set up and will for all we know be getting in their first patients as I write. Only 120 or thereabouts needed so given the rate of infections in hampshire and surrounding counties which CRN Wessex covers should not be too difficult. All of this and results within months not years!. You need to have a little more faith in what SNG are doing or sell and go mate. Either way i think Mr Filter is hovering over you again.
Ghia ,
No , they did'nt specifically say this but the logic is there to determine that this should be the case .
Summer is vague ...starts in June
I found it interesting that Richard was very specific with the timeline for the hospital results , July .... with 2 patients yet to be recruited and the follow up period of 14 after :-)
With the COPD , all we have to do is open up the database and do the statistics so SNG should have these in JUNE
Ghia thats how i understood it as well, Nopu can you elaborate on ur point pls, thx
The change of plan is intriguing ....
1) pharma are knocking on the door to finance P3 trial but want a sneak look at interim results to confirm the amount of the deal
2) .........
3 )..........
Were we expecting the COPD before or after COVID?
Appreciate 18 March RNS stated the COPD trial was paused but does that necessarily mean COVID was definitely coming first?
Nolupus - Did they specifically say COPD first?
I read:
C19 - July
COPD - Summer
At Home - Hopefully summer dependant on speed of recruitment
X66jrp,
With what we were told yesterday, the COPD interim results should be first to be revealed followed by the covid hospital results and lastly the home trial results
Up to now , we were expecting the COPD results after the COVID results ...
Nolupus - Are you referencing the COPD readout or the at Home Trials?
COPD seems like an obvious opportunity to access data early if 100 patients is good enough for the c19 trial, 109 should be fine for COPD.
I believe At Home was always the goal but they had to prove out the safety aspect in a hospital setting first.
It's significant that we are now allowed to dose High Risk patients 50+, that tells us there are no obvious adverse side effects being caused in the Hospital trial or COPD trial.
Nice if you would share your thoughts.
Nolupus - whats the question exactly? Its a bit too vague asking this imo.
Why did SNG change the game plan ?