Ben Richardson, CEO at SulNOx, confident they can cost-effectively decarbonise commercial shipping. Watch the video here.
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I think we would have been informed by now if anyone had crossed a % in the recent placing.
That would indicate that SL has increased his holding by at least 12 million shares to stay above 9%
Saying that Raymond John McKeeve used to take weeks if not months to issue a TR-1 so who knows. SL is normally very prompt though.
Maybe one of our new investors topping up before informing the market of their holding , maybe Rns tomorrow
It looks like a buy
They previously commented that an RNS cost them about £5K. So they only put them out when needed.
£53k trade. is it a buy or sell
gixer,
I do think so. If you see other company like SAR they normally issue a RNS when they get a patent approved. I think it also a good publicity as well.
Good to see the big guns are on CV now.
Remains to be seen what DSM do with it - going on previous DSM performance FF might be available for CV35
W$
Don't disagree wellsite but having a patent doesn't mean you can make a health claim.
Nice find BTW :)
gixer
for me
“muscle soreness” is far more consumer friendly than exercise induced inflammation. Would look good on bottle of gatorade
W$
Platelet hyperactivity in COVID-19: Can the tomato extract fruitflow® be used as an antiplatelet regime?
Abstract
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus is now considered a global public health threat. The primary focus has been on reducing the viral spread and treating respiratory symptoms; as time goes on, the impact of COVID-19 on neurological and haemostatic systems becomes more evident. The clinical data suggest that platelet hyperactivity plays a role in the pathology of COVID-19 from its onset and that platelets may serve critical functions during COVID-19 progression. Hyperactivation of blood platelets and the coagulation system are emerging as important drivers of inflammation and may be linked to the severity of the ‘cytokine storm’ induced in severe cases of COVID-19, in which disseminated intravascular coagulation, and platelet hyperactivity are associated with poor prognosis and increased risk of mortality.
We propose that targeting platelet hyperactivity in the early stages of COVID-19 infection may reduce the immunothrombotic complications of COVID-19 and subdue the systemic inflammatory response. Lowering baseline platelet activity may be of particular importance for higher-risk groups. As an alternative to antiplatelet drugs, an inappropriate intervention in public health, we propose that the dietary antiplatelet agent Fruitflow®, derived from tomatoes, may be considered a suitable therapy. Fruitflow® contains antiplatelet and anti-inflammatory compounds that target the mechanisms of platelet activation specific to COVID-19 and can be considered a safe and natural antiplatelet regime.
https://www.sciencedirect.com/science/article/abs/pii/S0306987720333715?fbclid=IwAR3j_hzwVFy_bIjH_6hMwQkmQ9lo_Q2p3hpBwdFlNq6r1QWio9b52M3FvEA
DP64, The company, as far as I am aware, has never issued an RNS for any Patents and probably never will. It does however give updates on the status of Patents and this was included in the final results.
"The use of Fruitflow with nitrates in mitigating exercise-induced inflammation and for promoting recovery from intense exercise. The patent was first granted by the UK IPO (Intellectual Property Office) in May 2017, and further patents have been granted in Australia, China, New Zealand and Japan. Applications have been accepted for grant in Europe, the US and the Philippines, and further patents for this formulation are being sought in eight other territories, with potential patent protection out to December 2033."
As you can see, it would get a bit messy issuing an RNS every time one of our Patents was granted in another country.
So what on earth prevent them not to provide a RNS with this wondaful news. I think IF wanted to give cheap shares to his friends during the fund raise. Come on IF please look after the long term share holder as well not only your close friends.
Great find W$
Not sure if already spotted, looks like we have patent granted in states since
27 Oct
METHODOFTREATINGAHUMAN SUFFERING FROM POST EXERCISE MUSCLE SORENESS
https://patentimages.storage.googleapis.com/df/74/d9/c358b5787c9163/US10813968.pdf
https://patents.google.com/patent/US10813968B2/en
W$
Asim is still a consultant for Provexis.
https://www.provexis.org/about-provexis/scientific-advisory-board/
As for acceleration of blue hat. I don't think you can.
Clinical trials must be conducted in China for blue hat and this isn't a clinical trial.
Hi gixer,
That's very interesting. However Asim is not part of Provexis or By-Health. Could By-Health use this data to accelerate the Blue Hat approval?
Now published
Role of Gut Microbiota and Their Metabolites on Atherosclerosis, Hypertension and Human Blood Platelet Function: A Review
https://www.mdpi.com/2072-6643/13/1/144/htm?fbclid=IwAR3B3_PafwhVn7bpCMBBjxzc2zcmBjmzs7fqut_-Gm5xsDW-AvsSYk_DCDw
New function research
http://www.binh.cn/#/index3?id=2b1d9f2bbde14a8b9f34b425cb40515f
Lots of info on FF including Video in Chinese.
Felix on By-Health, DSM, Provexis and Fruitflow @10min 30 (Chinese)
http://www.binh.cn/#/BINHbbsDetails?id=425bc64a48c24c65ab0480e6fc1310f5&menuItemId=b37766f3e05611ea8e990242ac116a0b
Perhaps davidxie77 could help with any info we don't know?
Thanks.
Just a reminder of some of the Registered Clinical Trials, Publications and Patents found relating to By-Health and Fruitflow in China (except for the last Patent)
Registered Clinical Trials.
Water-soluble tomato extract improves platelet function in subjects with metabolic syndrome: a randomized clinical trail
Date of Registration:2020-12-02
http://www.chictr.org.cn/showprojen.aspx?proj=64530
Effect of combination of Fruitflow and aspirin on platelet function and endothelial cells
Date of Registration:2020-07-13
http://www.chictr.org.cn/showprojen.aspx?proj=56370
Human intervention study on dietary intake of water-soluble tomato extract
Date of Registration:2017-10-10
http://www.chictr.org.cn/showprojen.aspx?proj=22104
Effect of water-soluble tomato extract on hypercholesterolemia
Date of Registration:2018-04-27
http://www.chictr.org.cn/showprojen.aspx?proj=27052
Investigation of the Anti-hypertensive Role of Specific Plant Extracts in Hypertenison Patients
Date of Registration:2018-05-04
http://www.chictr.org.cn/showprojen.aspx?proj=27048
Publications
The water-soluble tomato concentrate Fruitflow inhibits its activation, aggregation and thrombosis by regulating the platelet PI3K/Akt and MAPKs signaling pathways
http://www.cnki.com.cn/Article/CJFDTotal-ZSYK202002011.htm
Inhibitory effect of Fruitflow on platelet function: a randomized placebo-controlled trial in elderly subjects
https://www.researchsquare.com/article/rs-95541/v1
Fruitflow attenuates human platelet granule secretion through down-regulating Src/PLC?2/PKC signaling pathway
https://www.researchsquare.com/article/rs-17401/v1
Toxicological Evaluation of Edible Safety of Water-soluble Tomato Concentrate (Fruitflow?)
http://www.fx361.com/page/2019/1205/6076972.shtml
Effects of water-soluble tomato concentrate on platelet aggregation
https://www.wjtcm.net/article.asp?issn=2311-8571;year=2019;volume=5;issue=4;spage=260;epage=268;aulast=Zhan
Study on the Antioxidant and Auxiliary Effects of Water-soluble Tomato Concentrate in Lowering Blood Lipid
https://r.cnki.net/kcms/detail/detail.aspx?filename=SPAJ202013071&dbcode=CRJT_CJFD&dbname=CJFDAUTO&v
Study on the anti-platelet aggregation effect of water-soluble tomato concentrate
http://cdmd.cnki.com.cn/Article/CDMD-84502-1019240650.htm
Patents
WO2020077747 - COMPOSITION FACILITATING LOWERING OF BLOOD PRESSURE AND DIETARY SUPPLEMENT
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020077747&_cid=P11-KJGTMR-22408-1
CN109380728 - COMPOSITION AND HEALTH-CARE FOOD WITH AUXILIARY BLOOD PRESSURE LOWERING EFFECT
https://patentscope.wipo.int/search/en/detail.jsf?docId=CN238963528&_cid=P11-KJGTMR-22408-1
Not By-Health
CN108524664 - COMPOSITION WITH INTESTINAL AND CARDIOVASCULAR REGULATING FUNCTION AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF
https://patentscope.wipo.int/search/en/detail.jsf?docId=CN228767168&_cid=P11-KJGTMR-22408-1
Not sure why they haven't posted on any of their own study results. Yet.
Hi gixer,
Many thanks for the the post. Very good find. Looks like things are getting place for something big.
I Suppose if it is later in the month they might be waiting for news from CBEC, Blue hat , or new alliances who knows !
Have no idea on the results. But the new and old investors obviously see the near to mid term prospects for them to invest a million pounds during these difficult times.
Xiaotang Nutrition Research Institute
Official account of BY-HEALTH Institute of Nutrition and Health
https://www.zhihu.com/org/xiao-tang-ying-yang-yan-jiu-yuan-77
Couple of posts on the 31st
https://zhuanlan.zhihu.com/p/340843021
https://zhuanlan.zhihu.com/p/340833513
and one on the 23-10-2020
https://zhuanlan.zhihu.com/p/267263667
Hope you are right regarding the results but my money is on the 29th.