The latest Investing Matters Podcast episode featuring Jeremy Skillington, CEO of Poolbeg Pharma has just been released. Listen here.
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Thank you. Your order has been received.
Order number: 157949
Date: 8th January 2021
Whats with all these little trades again.
It appears that our new and existing investors have not breached the 3% notifiable interest threshold , a bit surprising! but better for all shareholders that no one person holds such a large percentage of our company , I suppose someone could hold 66m shares and not have to inform the market .Have any of our large holders on here increased their holdings ?
I just went to this are shared it on Facebook. I recommend everyone else does.
Tweet from Asim Duttaroy, sorry if already posted or old news.
https://authors.elsevier.com/sd/article/S0306-9877(20)33371-5#.X_X_zX0lAL0.twitter
Use of tomato extract as antihypertensive agent and process for making water soluble sugar free tomato extract
15Dec
https://patents.google.com/patent/US10864241B2/en
W£££££
And post lol
Getting the multiple trade treatment again I see.
Getting the multiple trade treatment again I see.
Now they will sell, at .848.
I suggest that the .76 trades were all sells, but the huge trade is deliberately ambiguous.
Fun and games
Anyone find a reference to it at FF website ?
It's only an article in A JOURNAL.
They've already informed us that it is being studied, but, to be a legal health claim, would take a long time and a lot of money.
We all want success, but the company is bounded by responsibilities. An opinion in a journal is useful, but not backed up by published papers.
Yes fully agreed that once this paper is published there should be a RNS to highlight that we have a miracle product to help the COVID-19 sufferer. IF should think that with this information it could save many lives. So it is moral duty of IF to publicise Fruitflow to help people who got this terrible virus.
and a Happy New Year to you as well Sweetp.
They don't want to sell me any at .76
Morning all.
I'm not a sharesholder anymore , not since the days of the two fruit juices that I use to buy by the bucket load. I so believed in the product and the benefits of FF but lost patience after the split resulting in SIS.
Why were the fruit juices discontinued? I always thought that they were onto a winner there!
Thanks in advance
Message for gixer.happy new year to you and I would like to thank you for all the effort in supplying us with invaluable information.I still hold 55 mill shares and will buy more soon as I think we are so close to many many new opportunities.again many thanks
I agree wellsite. More should be made of this Medical Hypotheses.
gixer
I think this publication justifies an RNS - people read RNS’s .........
.....nothing else seems to be working re raising awareness of the life saving benefits of FF if the flat monthly FF+ order numbers are anything to go by
W$
ResearchGate
ResearchGate is the professional network for scientists and researchers. Over 19 million members from all over the world use it to share, discover, and discuss research. We're guided by our mission to connect the world of science and make research open to all.
To summarise, the consumption of antiplatelet tomato components
as Fruitflow® reduces platelet hyperactivity and inflammation and may
also help prevent endothelial dysfunction. An array of extensive
basic, mechanistic, compositional, and human trials is testimony to its
vascular benefits. Its modes of action are appropriate for use against
platelet activation caused by SARS-CoV-2, targeting P-selectin and integrin aIIb/ß3 activation, and the TF-thrombin-driven amplification of coagulation. We suggest that consuming Fruitflow®, especially before or
during the early stages of COVID-19 illness, may have an effect on the
severity of illness experienced. It may particularly benefit people who
are more vulnerable to the development of endothelial / platelet dysfunction. It is a safe dietary antiplatelet and should be investigated as a
potentially useful intervention for prevention of thrombotic disorders in
COVID-19.
................................also showed the effects of aqueous tomato extract on pro-inflammatory cytokine expression in LPS-activated monocyte-derived THP-1
macrophages. Cytokines TNF-a and IL-1ß were suppressed, along with
activation of NF-?B. Fruitflow® may also protect the endothelium
through its effects on intercellular adhesion molecule-1 (ICAM-1) and
vascular cell adhesion molecule-1 (VCAM-1). These two critical adhesion molecules are expressed on endothelial cells and mediate adhesion
of leucocytes and their interactions with inflamed endothelial cells, leading to endothelial damage [45]. Schwager et al. (2016) showed that
Fruitflow® significantly decreased the production and the gene expression of ICAM-1 and VCAM-1 in activated HUVEC [43]. This suggests
that Fruitflow® may be capable of altering some of the pathologies typically seen in endothelial dysfunction, a typical response to SARS-CoV-2.
Fruitflow® is a dietary antiplatelet, with a reversible mode of action
and a gentler antiplatelet effect than antiplatelet drugs such as aspirin,
clopidogrel, prasugrel, etc. These characteristics render it suitable for
use as a daily preventative antiplatelet regime where antiplatelet drugs
are inappropriate [46,47]. The cumulative antiplatelet effect of aspirin,
when taken daily, is well known and reflects its irreversible disabling
of platelet COX-1 and associated signalling. Fruitflow®’s effects are not
cumulative in this way, as its effects do not irreversibly disable platelet
signalling pathways. As a result, Fruitflow® does not extend the bleeding times in the same way that antiplatelet drugs can. This is illustrated
by an intervention study involving 47 healthy subjects, which showed
that overall, daily aspirin supplementation may be viewed as approximately three times as productive as daily Fruitflow® supplementation,
but is accompanied by an average increase in time to form a primary
clot in flowing blood (PFA-100 closure time) of 135% [42]. In contrast,
Fruitflow® supplementation increases the time to clot by only 40%, so
that the parameter remains within its normal range. These more moderate effects, which can be related to the reversibility of the antiplatelet
action of Fruitflow® rather than its mode of action per se, render it a
possible option for use by the general population as a safe dietary antiplatelet.
One possibility is some pxs may be exercising stock options. Doing it now may be more tax efficient than doing it later as gains to now are PAYE and subsequent gains would be capital gains which would be much less.
BWTFDIK
Best price for a sell all day was 0.73 so it has to be a buy. But where were all the sells for them to buy. Wonder if it's a transfer buy/sell from one person to another sorted by an MM. weird