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Statement re US Patent Allowed

30 Jul 2007 07:00

PROTEOME SCIENCES plc PRESS RELEASE Allowance of US Patent on Isobaric Tandem Mass Tags‚® (TMT‚®) Allowance of European Patent (TMT2)

30 July 2007. Proteome Sciences plc ("Proteome Sciences") is pleased to announce that the USPTO has issued a Notice of Allowance for its US patent application in isobaric mass labelling for its tandem mass tags (TMT‚®) entitled "Mass Labels" Serial No. 10/221,666 (TMT1). The Notice of Allowance completes the final stage of patent examination and represents the form in which the patent will be granted. This follows grants of the corresponding cases in Australia, New Zealand, Canada and most recently in Europe. The US Patent contains broad claims to sets of isobaric mass tags.

The TMT1 Notice of Allowance in the US is a significant milestone for Proteome Sciences because it confers valuable intellectual property around isobaric mass tagging in another major market and enables the Company to approach entities using isobaric mass labels in the US and to alert them that they can obtain licences from Proteome Sciences for the manufacture or use of any type of isobaric mass tags in their research programmes. These licences will allow revenue to be generated from any applications in the field of isobaric mass tagging.

Proteome Sciences has also received a Rule 51(4) - Notice of Intention to Grant for its patent application entitled "Mass Labels", Serial No. 02767650.1 (TMT2) from the European Patent Office that was published on 21st May, 2007. The TMT2 European Patent claims isobaric mass tags with peptide structures and various methods of their use.

Commenting on the US Notice of Allowance, Christopher Pearce, CEO of Proteome Sciences said:

"The allowances of the TMT1 patents in the US and Europe have provided Proteome Sciences broad claims across the field of isobaric tandem mass tagging with the ability to now exploit TMT‚® in these substantial markets, both as a product, in its own right and for third party licences for the manufacture or use of any type of isobaric tandem mass tags.

The market and applications for isobaric mass tagging in quantitative mass spectrometry continues to grow at a rapid pace and we are delighted to have achieved such broad patent coverage in the major economies. The latest patent grants should now enable us to complete commercialisation of TMT‚® through outlicensing and to generate strong revenue through licence income, product sales and royalties."

Ends Notes to editors:

Proteome Sciences plc applies high sensitivity proteomics to identify and characterise differential protein expression in diseases for diagnostic, prognostic and therapeutic applications. It has discovered blood biomarkers principally for stroke, vCJD, BSE, brain damage, solid organ transplant rejection and Alzheimer's disease. The main focus of its research currently addresses neurological, neurodegenerative, oncology and cardiovascular conditions.

In addition to its own proprietary biomarkers, Proteome Sciences has developed ProteoSHOP‚® (Proteome Sciences High Output Proteomics), a toolbox that offers high sensitivity and high throughput gel and gel-free proprietary technologies for the identification and validation of potential biomarkers and drug targets, including specialisation in membrane proteins and protein phosphorylation.

The Company has developed a range of specialist reagents to improve the performance and quantitation of protein separation and characterisation with mass spectrometry, bioinformatics, statistics and pattern recognition. These include Sensitizer‚®, PST‚®, qPST¢â€ž¢ and TMT‚®. Proteome Sciences has patent allowances in the major global jurisdictions for isobaric tandem mass tags (TMT ‚®) for the manufacture and use of any type of isobaric mass tags.

Commercialisation is actively pursued across the portfolio of the Company's programmes and technologies with licensing deals signed in biomarkers for Stroke and TSEs and for ProteoSHOP‚®.

Proteome Sciences has its headquarters in Cobham, Surrey in the UK and has laboratories at Kings College Hospital, London and Frankfurt Innovations Zentrum (FIZ), Frankfurt. It employs 32 full time scientists in addition to its corporate and business development staff, and has collaborative research agreements with leading academic institutes. The Company is listed on the Alternative Investment Market.

For further information please visit www.proteomics.com .

Proteome Sciences plc

Dr. Ian Pike, Business Development Director

Email: ian.pike@proteomics.com

Christopher Pearce, Chief Executive Officer

Email: christopher.pearce@proteomics.com

Tel: +44 (0)1932 865065

Public Relations

IKON Associates Coast Communications

Adrian Shaw Matt Baldwin

Tel: +44 (0)1483 535102 Tel: +44 (0)1233 503200

Mobile: +44 (0)797 9900733 Mobile: +44 (0)7930 439739

Email: adrian@ikonassociates.com Email: matt@coastcommunications.com

Nominated Adviser

Teather & Greenwood

Gareth Price / Thilo Hoffman Tel: +44 (0)20 7426 9000

PROTEOME SCIENCES PLC
Date   Source Headline
26th Apr 20247:00 amRNSContract Win
10th Apr 20247:00 amRNSFinal Results
2nd Jan 20247:00 amRNSCompletion of new facility in San Diego
30th Nov 20237:00 amRNSTrading Update
2nd Oct 20237:00 amRNSLaunch of Single Cell Proteomics Services
30th Aug 20232:14 pmRNSInvestor Presentation
25th Aug 20237:00 amRNSInterim Results
1st Jun 20239:43 amRNSRepayment of Loan
17th May 20231:05 pmRNSResult of AGM
17th May 20237:00 amRNSAGM Statement
12th May 20237:00 amRNSExpansion into the US
14th Apr 202310:45 amRNSDirector/PDMR Shareholding
6th Apr 202311:34 amRNSDirector/PDMR Shareholding
6th Apr 202310:30 amRNSInvestor Presentation
4th Apr 20237:00 amRNSFinal Results
29th Mar 20237:00 amRNSNotice of Results
6th Mar 20234:35 pmRNSPrice Monitoring Extension
20th Feb 20237:00 amRNSTrading Update
5th Jan 20237:00 amRNSMilestone Payment for TMT®/TMTpro™ Sales
1st Dec 20224:38 pmRNSGrant of Options and PDMR/director shareholdings
12th Oct 20227:00 amRNSGrant of Options and PDMR/director shareholdings
4th Oct 20227:00 amRNSChange of Auditor
20th Sep 20224:40 pmRNSSecond Price Monitoring Extn
20th Sep 20224:35 pmRNSPrice Monitoring Extension
18th Aug 20227:00 amRNSAppointment of Chief Financial Officer
11th Aug 20227:00 amRNSInvestor Presentation
4th Aug 20227:00 amRNSInterim Results
3rd Aug 20227:00 amRNSMilestone towards Single Cell Proteomics services
26th May 20229:04 amRNSChange of Registered Office
16th May 20221:24 pmRNSResult of AGM
16th May 20227:00 amRNSAGM Statement
12th May 20227:00 amRNSSubstantial Contract Win
26th Apr 20224:45 pmRNSDirector/PDMR Shareholding
21st Apr 20225:13 pmRNSDirector/PDMR Shareholding
11th Apr 20227:00 amRNSInvestor Presentation
1st Apr 20226:01 pmRNSDirector shareholding
31st Mar 20227:09 amRNSFinal Results
30th Mar 202211:24 amRNSLoan amendment
29th Mar 20227:00 amRNSNotice of Results
16th Feb 20224:40 pmRNSSecond Price Monitoring Extn
16th Feb 20224:35 pmRNSPrice Monitoring Extension
3rd Feb 20227:00 amRNSTrading Update
31st Dec 202112:36 pmRNSPrice Monitoring Extension
20th Dec 20217:00 amRNSSubstantial Contract Win
9th Dec 20214:41 pmRNSSecond Price Monitoring Extn
9th Dec 20214:36 pmRNSPrice Monitoring Extension
29th Nov 20214:36 pmRNSPrice Monitoring Extension
26th Nov 20214:36 pmRNSPrice Monitoring Extension
5th Nov 20217:00 amRNSPRM,INmune Bio presenting biomarker discovery data
3rd Nov 20214:41 pmRNSSecond Price Monitoring Extn

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