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Share Price Information for Proteome (PRM)

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Press Release

21 Feb 2007 09:41

PROTEOME SCIENCES plc PRESS RELEASE

21st February, 2007. Since the publication of the Interim Results, Proteome Sciences has made considerable progress as evidenced by recent developments in its intellectual property portfolio.

Matters have advanced at a particularly fast pace for the TMT‚® patents over the last few months as demonstrated in the December 2006 press releases on this subject. The notice of intention to grant in Europe is very important and the US appears to be close behind and in its final stages. The Board is very pleased with the way the process is proceeding.

The six press releases since October 2006, in particular the 18th December TMT‚® announcement that estimated that the market for isobaric mass tags (TMT‚®) over the patent life has increased to $0.6-$1.4bn, provide a strong indicator as to what is happening. In these circumstances, the Board remains confident of the successful commercialisation of TMT‚®.

As set out in the 2005 Report and Accounts, Proteome Sciences filed a claim for the breach of certain warranties provided by Sanofi-Aventis Deutschland GmbH

at the time of the acquisition of Xzillion Proteomics GmbH & Co. KG under which it is seeking damages of up to ¢â€š¬30m. This action is being vigorously pursued and the final submission is close to completion.

On 29th June 2006, the company entered into an agreement with C.D.J. Pearce, the Chief Executive of the Company, under which he agreed to provide a loan facility of up to ‚£2m to the company, available from 1st August, 2006 that carries interest at 2.5% above the base rate of Barclays Bank Plc. In order to provide additional working capital, Mr. Pearce has offered to increase the total size of the facility on the same terms to ‚£4m.

In view of the size of the loan facility, it has been agreed that security for the loan should be charged against the company's patent portfolio up to the value of the loan outstanding and that the loan should be convertible into ordinary shares of the Company at the lower of market price on the date of conversion or the average price over the lowest consecutive ten day trading period since the 29th June, 2006 (the date on which details of the original loan agreement were disclosed).

The Directors of the Company, (with the exception of Mr. Pearce who in view of his interest in the transaction, has taken no part in consideration thereof) having consulted with its nominated adviser in relation to the loan facility from Mr. Pearce, consider that the terms of this transaction are fair and reasonable insofar as shareholders are concerned.

The provision of this facility should allow the Company to complete the successful outlicencing of TMT‚® and to see it through to the revenue anticipated from its biomarker portfolio, ProteoSHOP‚® activities and from the warranty claim.

Ends Notes to editors: Proteome Sciences plc

Proteome Sciences, a global leader in applied proteomics, uses high sensitivity proprietary technologies to detect differentially expressed proteins in diseases. The protein biomarkers discovered in body fluids or tissues are validated, developed and commercialised as diagnostic, prognostic or therapeutic products through strategic alliances and out-licensing.

Through its unique ProteoSHOP‚® toolbox, Proteome Sciences provides high sensitivity/high throughput proteomics solutions, including traditional two dimensional gel-based electrophoresis (2DE) and proprietary gel-free protein sequence tag technologies (PST‚®, qPST¢â€ž¢& TMT‚®), to major pharma, biotechnology and diagnostic companies, to discover and exploit protein biomarkers. Sensitizer‚® chemical mass tags have been developed separately as a series of stand-alone reagents.

For further information please visit www.proteomics.com.

Enquiries: Proteome Sciences plc

Christopher Pearce, Chief Executive Officer

Email: christopher.pearce@proteomics.com

James Malthouse, Finance Director

Email: james.malthouse@proteomics.com

Tel: +44 (0)1932 865065

Public Relations for Proteome Sciences

IKON Associates Adrian Shaw

Tel: +44 (0)1483 535102

Mobile: +44 (0)797 9900733

Email: adrian@ikonassociates.com

PROTEOME SCIENCES PLC
Date   Source Headline
26th Apr 20247:00 amRNSContract Win
10th Apr 20247:00 amRNSFinal Results
2nd Jan 20247:00 amRNSCompletion of new facility in San Diego
30th Nov 20237:00 amRNSTrading Update
2nd Oct 20237:00 amRNSLaunch of Single Cell Proteomics Services
30th Aug 20232:14 pmRNSInvestor Presentation
25th Aug 20237:00 amRNSInterim Results
1st Jun 20239:43 amRNSRepayment of Loan
17th May 20231:05 pmRNSResult of AGM
17th May 20237:00 amRNSAGM Statement
12th May 20237:00 amRNSExpansion into the US
14th Apr 202310:45 amRNSDirector/PDMR Shareholding
6th Apr 202311:34 amRNSDirector/PDMR Shareholding
6th Apr 202310:30 amRNSInvestor Presentation
4th Apr 20237:00 amRNSFinal Results
29th Mar 20237:00 amRNSNotice of Results
6th Mar 20234:35 pmRNSPrice Monitoring Extension
20th Feb 20237:00 amRNSTrading Update
5th Jan 20237:00 amRNSMilestone Payment for TMT®/TMTpro™ Sales
1st Dec 20224:38 pmRNSGrant of Options and PDMR/director shareholdings
12th Oct 20227:00 amRNSGrant of Options and PDMR/director shareholdings
4th Oct 20227:00 amRNSChange of Auditor
20th Sep 20224:40 pmRNSSecond Price Monitoring Extn
20th Sep 20224:35 pmRNSPrice Monitoring Extension
18th Aug 20227:00 amRNSAppointment of Chief Financial Officer
11th Aug 20227:00 amRNSInvestor Presentation
4th Aug 20227:00 amRNSInterim Results
3rd Aug 20227:00 amRNSMilestone towards Single Cell Proteomics services
26th May 20229:04 amRNSChange of Registered Office
16th May 20221:24 pmRNSResult of AGM
16th May 20227:00 amRNSAGM Statement
12th May 20227:00 amRNSSubstantial Contract Win
26th Apr 20224:45 pmRNSDirector/PDMR Shareholding
21st Apr 20225:13 pmRNSDirector/PDMR Shareholding
11th Apr 20227:00 amRNSInvestor Presentation
1st Apr 20226:01 pmRNSDirector shareholding
31st Mar 20227:09 amRNSFinal Results
30th Mar 202211:24 amRNSLoan amendment
29th Mar 20227:00 amRNSNotice of Results
16th Feb 20224:40 pmRNSSecond Price Monitoring Extn
16th Feb 20224:35 pmRNSPrice Monitoring Extension
3rd Feb 20227:00 amRNSTrading Update
31st Dec 202112:36 pmRNSPrice Monitoring Extension
20th Dec 20217:00 amRNSSubstantial Contract Win
9th Dec 20214:41 pmRNSSecond Price Monitoring Extn
9th Dec 20214:36 pmRNSPrice Monitoring Extension
29th Nov 20214:36 pmRNSPrice Monitoring Extension
26th Nov 20214:36 pmRNSPrice Monitoring Extension
5th Nov 20217:00 amRNSPRM,INmune Bio presenting biomarker discovery data
3rd Nov 20214:41 pmRNSSecond Price Monitoring Extn

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