Proteome Regulatory News (PRM)

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

2. Reason for the notification  (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights

ü

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):___________________________________________

3. Full name of person(s) subject to the notification obligation:

Helium Special Situations Fund

4. Full name of shareholder(s) (if different from 3.):

5. Date of the transaction (and date on which the threshold is crossed or reached if different):

28/02/2014

6. Date on which issuer notified:

28/02/2014

7. Threshold(s) that is/are crossed or reached:

5%

8. Notified details:

n/a

A: Voting rights attached to shares

Class/type of shares

 if possible using the ISIN CODE

Situation previous to the Triggering transaction

Resulting situation after the triggering transaction

Number of Voting Rights

Number of shares

Number of voting rights

% of voting rights

Direct

Indirect

Direct

Indirect

GB0003104196

7'890'000

7'890'000

11'423'385

11'423'385

 -

5.34%

-

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ Conversion Period/ Date

Number of voting rights that may be acquired if the instrument is exercised/ converted.

% of voting rights

-

-

-

-

-

Total (A+B)

Number of voting rights

% of voting rights

11'423'385

5.34%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:

n/a

Proxy Voting:

10. Name of the proxy holder:

n/a

11. Number of voting rights proxy holder will cease to hold:

n/a

12. Date on which proxy holder will cease to hold voting rights:

n/a

13. Additional information:

-

14. Contact name:

Christian Benz, ISPartners (Co-Advisor to the Helium Sp. Sit. Fund)

15. Contact telephone number:

+41 43 888 7342