Aptitude Regulatory News (APTD)

1.

Name of the issuer

2.

State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

MICROGEN PLC

(i)

3.

Name of person discharging managerial responsibilities/director

4.

State whether notification relates to a person connected with a person discharging managerial responsibilities/director named in 3 and identify the connected person

TOM CRAWFORD

N/A

5.

Indicate whether the notification is in respect of a holding of the person referred to in 3 or 4 above or in respect of a non-beneficial interest

6.

Description of shares (including class), debentures or derivatives or financial instruments relating to shares

SEE 3 ABOVE

ORDINARY SHARES OF 5P EACH

7.

Name of registered shareholders(s) and, if more than one, the number of shares held by each of them

8

State the nature of the transaction

TOM CRAWFORD

EXERCISE OF SHARE OPTIONS

9.

Number of shares, debentures or financial instruments relating to shares acquired

10.

Percentage of issued class acquired (treasury shares of that class should not be taken into account when calculating percentage)

70,005 SHARES

0.09%

11.

Number of shares, debentures or financial instruments relating to shares disposed

12.

Percentage of issued class disposed (treasury shares of that class should not be taken into account when calculating percentage)

N/A

N/A

13.

Price per share or value of transaction

14.

Date and place of transaction

70,005 SHARES EXERCISED AT AN OPTION PRICE OF 5P

20 AUGUST 2010, UK

15.

Total holding following notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage)

16.

Date issuer informed of transaction

191,566 SHARES â€" 0.24%

20 AUGUST 2010

17

Date of grant

18.

Period during which or date on which it can be exercised

N/A

N/A

19.

Total amount paid (if any) for grant of the option

20.

Description of shares or debentures involved (class and number)

N/A

N/A

21.

Exercise price (if fixed at time of grant) or indication that price is to be fixed at the time of exercise

22.

Total number of shares or debentures over which options held following notification

N/A

N/A

23.

Any additional information

24.

Name of contact and telephone number for queries

INFORMATION IS BASED ON THE COMPANY’S CURRENT ISSUED SHARE CAPITAL WHICH IS 80,407,749

ANJUM SIDDIQI, COMPANY SECRETARY, MICROGEN PLC - 01252 772 326

1.

Name of the issuer

2.

State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

MICROGEN PLC

(i)

3.

Name of person discharging managerial responsibilities/director

4.

State whether notification relates to a person connected with a person discharging managerial responsibilities/director named in 3 and identify the connected person

CLARE GROOM

N/A

5.

Indicate whether the notification is in respect of a holding of the person referred to in 3 or 4 above or in respect of a non-beneficial interest

6.

Description of shares (including class), debentures or derivatives or financial instruments relating to shares

SEE 3 ABOVE

ORDINARY SHARES OF 5P EACH

7.

Name of registered shareholders(s) and, if more than one, the number of shares held by each of them

8

State the nature of the transaction

CLARE GROOM

EXERCISE OF SHARE OPTIONS & PART SALE OF SHARES

9.

Number of shares, debentures or financial instruments relating to shares acquired

10.

Percentage of issued class acquired (treasury shares of that class should not be taken into account when calculating percentage)

46,670 SHARES

0.06%

11.

Number of shares, debentures or financial instruments relating to shares disposed

12.

Percentage of issued class disposed (treasury shares of that class should not be taken into account when calculating percentage)

35,990 SHARES

0.04%

13.

Price per share or value of transaction

14.

Date and place of transaction

46,670 SHARES EXERCISED AT AN OPTION PRICE OF 5 PENCE

35,990 SHARES SOLD AT A PRICE OF 85 PENCE

20 AUGUST 2010, UK

23 AUGUST 2010, UK

15.

Total holding following notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage)

16.

Date issuer informed of transaction

46,851 SHARES â€" 0.06%

20 AUGUST 2010

17

Date of grant

18.

Period during which or date on which it can be exercised

N/A

N/A

19.

Total amount paid (if any) for grant of the option

20.

Description of shares or debentures involved (class and number)

N/A

N/A

21.

Exercise price (if fixed at time of grant) or indication that price is to be fixed at the time of exercise

22.

Total number of shares or debentures over which options held following notification

N/A

N/A

23.

Any additional information

24.

Name of contact and telephone number for queries

INFORMATION IS BASED ON THE COMPANY’S CURRENT ISSUED SHARE CAPITAL WHICH IS 80,407,749

ANJUM SIDDIQI, COMPANY SECRETARY, MICROGEN PLC - 01252 772 326

1.

Name of the issuer

2.

State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

MICROGEN PLC

(i)

3.

Name of person discharging managerial responsibilities/director

4.

State whether notification relates to a person connected with a person discharging managerial responsibilities/director named in 3 and identify the connected person

MARTIN REDINGTON

N/A

5.

Indicate whether the notification is in respect of a holding of the person referred to in 3 or 4 above or in respect of a non-beneficial interest

6.

Description of shares (including class), debentures or derivatives or financial instruments relating to shares

SEE 3 ABOVE

ORDINARY SHARES OF 5P EACH

7.

Name of registered shareholders(s) and, if more than one, the number of shares held by each of them

8

State the nature of the transaction

MARTIN REDINGTON

EXERCISE OF SHARE OPTIONS AND PART SALE OF SHARES

9.

Number of shares, debentures or financial instruments relating to shares acquired

10.

Percentage of issued class acquired (treasury shares of that class should not be taken into account when calculating percentage)

46,670 SHARES

0.06%

11.

Number of shares, debentures or financial instruments relating to shares disposed

12.

Percentage of issued class disposed (treasury shares of that class should not be taken into account when calculating percentage)

36,682 SHARES

0.05%

13.

Price per share or value of transaction

14.

Date and place of transaction

46,670 SHARES EXERCISED AT AN OPTION PRICE OF 5 PENCE

36,682 SHARES SOLD AT A PRICE OF 85 PENCE

 

20 AUGUST 2010, UK

23 AUGUST 2010, UK

15.

Total holding following notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage)

16.

Date issuer informed of transaction

9,988 SHARES â€" 0.01%

20 AUGUST 2010, UK

17

Date of grant

18.

Period during which or date on which it can be exercised

N/A

N/A

19.

Total amount paid (if any) for grant of the option

20.

Description of shares or debentures involved (class and number)

N/A

N/A

21.

Exercise price (if fixed at time of grant) or indication that price is to be fixed at the time of exercise

22.

Total number of shares or debentures over which options held following notification

N/A

N/A

23.

Any additional information

24.

Name of contact and telephone number for queries

INFORMATION IS BASED ON THE COMPANY’S CURRENT ISSUED SHARE CAPITAL WHICH IS 80,407,749

ANJUM SIDDIQI, COMPANY SECRETARY, MICROGEN PLC - 01252 772 326

1.

Name of the issuer

2.

State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

MICROGEN PLC

(i) ONLY

3.

Name of person discharging managerial responsibilities/director

4.

State whether notification relates to a person connected with a person discharging managerial responsibilities/director named in 3 and identify the connected person

ANJUM SIDDIQI

N/A

5.

Indicate whether the notification is in respect of a holding of the person referred to in 3 or 4 above or in respect of a non-beneficial interest

6.

Description of shares (including class), debentures or derivatives or financial instruments relating to shares

SEE 3 ABOVE

ORDINARY SHARES OF 5P EACH

7.

Name of registered shareholders(s) and, if more than one, the number of shares held by each of them

8

State the nature of the transaction

ANJUM SIDDIQI

EXERCISE OF SHARE OPTIONS AND PART SALE OF SHARES

9.

Number of shares, debentures or financial instruments relating to shares acquired

10.

Percentage of issued class acquired (treasury shares of that class should not be taken into account when calculating percentage)

45,003 SHARES

0.06%

11.

Number of shares, debentures or financial instruments relating to shares disposed

12.

Percentage of issued class disposed (treasury shares of that class should not be taken into account when calculating percentage)

38,003

0.05%

13.

Price per share or value of transaction

14.

Date and place of transaction

23,335 SHARES EXERCISED AT AN OPTION PRICE OF 5 PENCE

21,668 SHARES EXERCISEDAT AN OPTION PRICE OF 46.83 PENCE

38,003 SHARES SOLD AT A PRICE OF 85 PENCE

20 AUGUST 2010, UK

20 AUGUST 2010, UK

23 AUGUST 2010, UK

15.

Total holding following notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage)

16.

Date issuer informed of transaction

7,000 SHARES â€" 0.01%

20 AUGUST 2010

17

Date of grant

18.

Period during which or date on which it can be exercised

N/A

N/A

19.

Total amount paid (if any) for grant of the option

20.

Description of shares or debentures involved (class and number)

N/A

N/A

21.

Exercise price (if fixed at time of grant) or indication that price is to be fixed at the time of exercise

22.

Total number of shares or debentures over which options held following notification

N/A

N/A

23.

Any additional information

24.

Name of contact and telephone number for queries

INFORMATION IS BASED ON THE COMPANY’S CURRENT ISSUED SHARE CAPITAL WHICH IS 80,407,749

ANJUM SIDDIQI, COMPANY SECRETARY, MICROGEN PLC - 01252 772 326

1.

Name of the issuer

2.

State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

MICROGEN PLC

(i) ONLY

3.

Name of person discharging managerial responsibilities/director

4.

State whether notification relates to a person connected with a person discharging managerial responsibilities/director named in 3 and identify the connected person

ELIZABETH SIPIERE

N/A

5.

Indicate whether the notification is in respect of a holding of the person referred to in 3 or 4 above or in respect of a non-beneficial interest

6.

Description of shares (including class), debentures or derivatives or financial instruments relating to shares

SEE 3 ABOVE

ORDINARY SHARES OF 5P EACH

7.

Name of registered shareholders(s) and, if more than one, the number of shares held by each of them

8

State the nature of the transaction

ELIZABETH SIPIERE

EXERCISE OF SHARE OPTIONS AND PART SALE OF SHARES

9.

Number of shares, debentures or financial instruments relating to shares acquired

10.

Percentage of issued class acquired (treasury shares of that class should not be taken into account when calculating percentage)

70,005 SHARES

0.09%

11.

Number of shares, debentures or financial instruments relating to shares disposed

12.

Percentage of issued class disposed (treasury shares of that class should not be taken into account when calculating percentage)

55,031 SHARES

0.07%

13.

Price per share or value of transaction

14.

Date and place of transaction

70,005 SHARES EXERCISED AT AN OPTION PRICE OF 5 PENCE

55,031 SHARES SOLD AT A PRICE OF 85 PENCE

20 AUGUST 2010, UK

23 AUGUST 2010, UK

15.

Total holding following notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage)

16.

Date issuer informed of transaction

14,974 SHARES â€" 0.02%

20 AUGUST 2010

17

Date of grant

18.

Period during which or date on which it can be exercised

N/A

N/A

19.

Total amount paid (if any) for grant of the option

20.

Description of shares or debentures involved (class and number)

N/A

N/A

21.

Exercise price (if fixed at time of grant) or indication that price is to be fixed at the time of exercise

22.

Total number of shares or debentures over which options held following notification

N/A

N/A

23.

Any additional information

24.

Name of contact and telephone number for queries

INFORMATION IS BASED ON THE COMPANY’S CURRENT ISSUED SHARE CAPITAL WHICH IS 80,407,749

ANJUM SIDDIQI, COMPANY SECRETARY, MICROGEN PLC - 01252 772 326

Name and signature of duly authorised officer of issuer responsible for making notification

ANJUM SIDDIQI

Date of notification:  23 AUGUST 2010

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