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The MCap went way over double £200m, so it was the correct decision at the time. Indeed, if we ever get on another p3 trial and pass it, then the value of the company should be in the billions, not millions. In a nutshell, the management are looking at the long-term value, not selling out cheap. Of course though, the sands of time are relentless as-is the cash-burn so they need to achieve a decisive route forward quickly otherwise potentially the company could disappear altogether.

https://www.youtube.com/watch?v=-rVV7rUv3p4

Tatty: What do you think they should have done differently? And what do you think they should do to progress further in 2023?

These are not loaded questions to berate you for "unfounded negativity" - I was as gutted as anyone on here when Sprinter failed - but I genuinely would like to know what you think could have/should change.

FWIW, I think that RM and the board are decent people and they are all undoubtedly very clever, with good backgrounds and industry connections. Whether this is enough to eventually deliver the goods remains to be seen. Its fair to say that there's not much concrete evidence so far... There was, however, a marked increase in "marketing" activity in the last quarter of 2022, some would see this as a positive, others as just globe-trotting "jollies" or the beginning of a last desperate throw of the dice.

One thing is for certain, we need some concrete positive news in the next few weeks. If not, then RM may be forced into more drastic moves to reduce the cash-burn to buy a bit of time and/or commence a fund-raise etc. Even this could prove ultimately futile though if the seeming lack of interest in Synairgen's "potential" product remains.

The wildcard in all this for me is Polygon. I hope they are as supportive as RM alluded to at the AGM and Eugene Reade alluded to in one of his interviews.

Jan/Feb will be interesting and determine if the company does have a future IMHO...

DYOR and good luck to all.

Thanks BG, sounds positive then. Will be interesting to see if anything comes of it.

Have we attended in (recent) previous years?

There seems to be a lot of excitement/anticipation for this conference. What am I missing? Has Mr Marsden been spotted signing official-looking papers with important-looking people?

XViolet - From the interim results RNS at the end of September. I presume the trial design they refer to would be Phase 3.
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The Group's available resources at the date of this report are sufficient to cover the Group's committed activities of interacting with platform and other investigator-led studies, designing a broad-spectrum antiviral clinical trial, engaging with pharmaceutical companies regarding collaboration/licensing opportunities for that broad indication and, if required, engaging with providers of any other type of funding (details of these activities, current operating expense levels to 30 June 2022 and working capital at 30 June 2022 can be found in the Operating and Financial Reviews). Regardless of the outcome of these activities, which are uncertain, the Group's available resources are sufficient to cover existing committed costs and the costs of these activities until at least 30 September 2023.

I did the same a few weeks back. The way he/she/it writes post after post after post of essentially the same thing coupled with the stupid poems confirmed to me that there was some sort of mental illness going on. Sad really.

Starting in the late 19th century there had been reports of the antibacterial properties of Penicillium mould

In 1928 Scottish physician Alexander Fleming at St. Mary's Hospital in London (now part of Imperial College) was the first to show that Penicillium rubens had antibacterial properties.

First successful use of pure penicillin was in 1942...

From Wikipedia, so don't blame me if it's a load of rubbish :-)

* dozen or so TRADES

Agree AJ316. I looked on here at about 3:45 before leaving work and there was the usual dozen or so shares and tumbleweed, got home at 4:30 to see over 100 trades and loads of buys... Seems very weird to me.

Great post Trinityman.

I must admit that in the last few days my "Synairgen Swingometer" has been spending more time towards the negative outlook side, rather than positive side. Mainly, I think, due to nothing seemingly coming up on the horizon now (even having conference talks planned has previously given some small crumbs of hope that things are at least ticking over) and also 2 large sells this morning didn't help...

However, reading your post has helped restore a bit of patience and perspective, so many thanks. ATB.

Nice work Elsol. Will be interesting to see if you get a response, please keep us informed. ATB.

Quite, Sativa...hopefully it's not a case of

"Christmas Time, Missed-a-Trial and Whine"

I'll get my coat.

My French isn't as good as it used to be, but it seems to suggest those drugs are on some sort of Temporary Authorisation list...which would appear to be at odds with Synairgens "SNG001 is not authorised for use anywhere in the world" line they've used on some recent RNSs.

Interesting find all the same, thank you.

I guess we just need to keep positive ourselves Doc83. I think it's fair to say that the Synairgen team have been knocking on some very high profile doors recently, so credit where it's due for that. It was always going to be a tall order for Synairgen to drive the agenda when reliant on others, as you say.
Hopefully some of the conversations have struck the right note with right people and hopefully there will be sufficient funding/trials/interest coming sooner than we think...God knows, we could do with some good fortune.

GLA!!

I had it on in the background for an hour or so, upto where they had an adjournment and there was nothing earthshattering that I heard. All the witnesses had a 5 min slot for a statement. All basically saying that we shouldn't take the foot off the gas when dealing with Covid and similar future emergencies. I did hear the need for "host targetted" therapeutics mentioned by one the ladies, which was good to hear. Will take another listen when I get a minute to make sure I didn't miss anything exciting.

I think even the most ardent RM supporters would be demanding his head on a pike way before the end of 2023 if no positive news is forthcoming soon.

Ref China, I'm not usually a fan of the Guardian, but spotted these on another board:

https://www.theguardian.com/world/2022/dec/14/china-says-spread-of-covid-impossible-to-track-as-infections-soar-in-beijing

Sounds like they're in a right state. Imagine if they had a trial over there which SNG001 could get on...we'd probably be able to recruit a million patients onto it by 5pm.

Last one for tonight....sorry to bombard you with lots of threads!!

I'm not sure if Synairgen attended this event on 15th/16th November but BARDA have put up some videos from it, and whilst possibly not directly relating to/applicable to Synairgen, they seem to give an interesting insight in how the industry ticks. I've just skimmed through a few and there's certainly a lot of mentions of "broad spectrum" and "host targetted therapeutics":

https://www.youtube.com/watch?v=h2h2wDh1bK8
https://www.youtube.com/watch?v=bXgM5bwIqAQ
https://www.youtube.com/watch?v=b-1O4NunDNo
https://www.youtube.com/watch?v=oV7aPqlgKXI

Bit of bed-time listening anyway...