Member Info for whimax

Lol.

Lol Jackpot. Yes, I could have timed it a bit better. Doh!

Bit like your top up at 4.30p? What’s 25% between friends eh. Lol

Nice finish. Up 6.5%

Still slightly better than 4.10p right enough, even with the spread! ;-)
You could average down Goofypete?

I assume this is the reason for the 10% Spread!! Ridiculous.

.......seem intent on tempting fate here today!!

I’ve said it before...........There Isn’t One!!

Volume still quite small (on the face of it) but once it picks up (FOMO could be any time) this could easily do 20-30% in a day.

Be very careful if you’re using Stops (see price action on ODX yesterday). If you think games have been played thus far, it’s about to get a whole lot more interesting.

This is a screaming buy at this level imo.

Just increased my holding by 10% via a SB. These are now my traders.

P.s. The playground stuff on here is embarrassing, to say the least. I expected much better of some, whilst other never change.

GL

It also has so much control over this share (due to tiny Nasdaq volume) that it’s capable of running this up, literally to almost anywhere it wants.

FWIW, I think the Bot is still on, but looks like it’s shifted to the buy side? Just my tuppence worth.

I post quite a bit on Stockwits in an attempt to promote TLSA and educate our American friends. In fact, 2 of the last 7 posts are mine ;-)

Not the easiest of tasks, but seems 1 or 2 might be starting to catch on.

If you read my post BM3, I’m saying I’m now understanding the importance of the CD3 part, which is what makes Foralumab unique. There are plenty fully human monoclonal antibodies out there, but Foralumab is the only one with anti CD3.

The recent patent of Foralumab for Crohns, but also very relevant to COVID.

This is the importance of the CD3 part (sorry, I’m only just catching on to this now) in Foralumab which is the ONLY Fully Human “Anti CD3” Monoclonal Antibody under development.

“Office (“USPTO”) has granted a patent on use and methods of treatment of Crohn’s disease with Foralumab, its proprietary fully human monoclonal antibody, and all other anti-CD3 monoclonal antibodies (mAb). The CD3 (cluster of differentiation 3) is a protein complex on T-cells, which is important for the regulation of the immune system“

https://www.globenewswire.com/news-release/2020/08/18/2079625/0/en/Tiziana-Granted-a-Patent-on-Methods-and-Use-of-Anti-CD3-Monoclonal-Antibodies-for-Treatment-of-Crohn-s-Disease.html

Thanks Greend100. Yes, you are correct. Foralumab is the ONLY Fully Human Anti CD3 Monoclonal Antibody currently in development in the world.

This is REGN-COV2 Monoclonal Antibody info from RNS they released the other day. How does this stack up against Foralumab? Anybody know?

To develop REGN-COV2, Regeneron scientists evaluated thousands of fully-human antibodies produced by the company's VelocImmune® mice, which have been genetically modified to have a human immune system, as well as antibodies identified from humans who have recovered from COVID-19. The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science. Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.

Has anybody seen any info on how Mr Trumps monoclonal antibodies were administered? Oral, nasal or intravenously? Key question imo.

POTUS now being given Dexamethasone!! Our Brazil trial starts this month.

Tiziana Life Sciences PLC (NASDAQ:TLSA, LON:TILS) has signed an agreement to use its “potentially transformative” approach to modulating the immune system in a human clinical study of patients with coronavirus (COVID-19).

Work will get underway in Brazil starting next month, with the company's drug, Foralumab, administered by nasal spray either on its own or in combination with an orally-taken anti-inflammatory called dexamethasone.

https://www.proactiveinvestors.co.uk/companies/news/929307/tiziana-life-sciences-to-conduct-covid-19-human-clinical-study-in-brazil-using-its-potentially-transformative-approach-to-modulating-the-immune-system-929307.html

From BBC news just now.

“President Trump is treated with the steroid dexamethasone after oxygen level drops on Friday and Saturday, his doctor says“

Same drug as we are partnering with in Brazil:-)

https://www.bbc.co.uk/news/live/world-54382914

http://www.businessmole.com/covid-19-tiziana-life-sciences/

Tiziana says they plan to administer TZLS-501 using a proprietary formulation technology. And they have already entered into a license for it in 2017 with the Swiss biotech company Novimmune.

Dr. Kunwar Shailubhai, the CEO & CSO of Tiziana Life Sciences, explains why this antibody shows lots of promise:

“We believe that the features of TZLS-501 provide distinct advantages for treatment of COVD-19 over other anti-IL-6R mAbs such as Actemra® and Kevzara® for treatment of COVID-19. The recent decision by researchers in China to add Actemra® to treatment guidelines for coronavirus patients with serious lung damage confirms the utility of anti-IL6R mAb. We are excited to move forward with our clinical development plan to expedite evaluation in patients as soon as possible.”

“Doctors and medical staff the world over will hold out hope that this can be an effective treatment for some of those worst affected by COVID-19, and hope that expediting the development of TZLS-501 is fruitful.“

Wow!!