RE: FFS what is wrong with the stock market!!19 Aug 2022 15:33
At the end of the day the trial did not achieve what they where hoping, more trials required. We might still get some money back, we might get zero. We are still in the dark and maybe will be for some time, that's why the SP is dropping back.
Although the trial did not achieve its primary endpoint, AZD1656 was associated with a decrease in deaths and a reduction in the duration of hospitalisation, as compared to Placebo. Immunophenotyping and immunochemistry indicated an immunomodulatory effect of AZD1656. The trial suggests a beneficial therapeutic effect of AZD1656 and identifies a new therapeutic concept: small molecule activation of endogenous homeostatic immune cells which themselves become the therapeutic agent within the body. Phase 2 trials of this size carry the risk of false positive results and confirmation of these results in a larger clinical trial is now required.