Our live Investing Matters Podcast Special which took place at the Master Investor Show discussing 'How undervalued is the UK stock market?', has just been released. Listen here.
Many backed them at 54p, issue is many people backed them at a higher value on information they gave/chose not to give.
LTH so this is in a drawer, but I can sympathise with anyone who bought above a pound. Basically AL is about as reliable source of information as picking a number using a dart board.
@pl given the audience I would have thought purple pills would generate the most ad revenue. It used to be mining equipment and bibles but those days are long gone.
Oh no it’s not
200 ex China
I don't feel well, I need to sit down. Just popped a rec on an Icecool post. Feels weird.
Oh happy days, great RNS, AND his Lordship returns with his usual comedy gold.
I’ve got the potatoes on the boil ready to make some mash to go with a good sausage thwacking.
I hope he’s been working on some good material. The old stuff,to be fair was awesome, just genius use of excel with fill colors and logarithmic scales, with a liberal use of bratwurst. I think we could be on the cusp of something spectacular, could we hope to see power point with clip art. Fingers crossed.
Big fan Mr O, welcome back.
Apes would imply intelligence.
More like sea-gulls, flapping around, getting excited over rubbish, making a lot of noise and s***ing on everyone else.
Bump. Interesting.
Here's a thought, maybe some are shorting Avacta and that could affect the share price, hence rules changing about shorinting being posted on the Avacta board.
on political posts, one thing to vote with the crap that was being spouted by people in positions which traditionally have a level of trust. It's another thing to think Brexit was a good thing thing looking around today, rather than a "get over it". Maybe an apology instead;-)
Once 6K phase 1a complete, will the results turn affect how other drugs using same delivery are tested.
Basically is next drug testing regime speeded up by 6K knowledge or will it lead its own independent existence.
Wondering how fast treatment 2,3….n come to market.
Deep verge I mean
Maybe this ?
https://blog.trialspark.com/what-is-body-surface-area-bsa-and-why-is-it-important/amp/
PL too true, big picture, that is very wise.
The point is a 2,2 dox equivalent in 6k is not the same as tumor being hit with that.
It actually might be higher in FAP tumor as it’s targeted and the 2,2 dose is not shared with rest of system. Might be less but still therapeutic.
On the beans, dox is like chili beans, some horrendous side effects. 6k is more your Jamie Oliver chick beans in a tomato sauce gently simmered for an hour, and smooth as silk .
We need to see PK report.
Sorry on phone, something odd with cut/paste
HH, years since I did enzyme action. Saturations talks about rates. If enzyme does 100 per hour, that’s saturated. Adding more drug does not increase rate of cleavage.If body is getting rid of some of drug also it means 100% of drug is not cleaved, some is excreted.
Do not ignore saturation, I think you might mean exhaustion.
13m thanks, more meant unlikely to be maximums.
HH, years since I did enzyme action. Saturations talks about rates. If enzyme does 100 per hour, that’s saturated. Adding more drug does. It increase rate of cleavage.If body is getting rid of some of drug also it means 100 of drug is not cleaved, some is excreted.
Might be wrong, happy to be corrected
It’s a simplified picture to paint when we say 2,2 levels. Depends on how much is cleaved before excretion. FAP may get saturated, MTD, never found. From what Fiona said that’s not the case yet and increase in blood effects are occurring.
Like you say therapeutic levels, great news. Therapeutic levels can mean a lot of things, maybe minimums. Hopefully close to full load converted but that is obfuscated until paper published.
P1a will take the time it takes, and better it continues than we think, ah sod it 2,2 is enough. Patients will benefit more on long term, we just need to hold.
RD, bad, very bad:-)
PL, thanks.
Everyone entitled to their opinion, care to say why is this meant to
a. make you feel better cos you missed it when it was 40p
b. you think someone will panic and start to sell
c. you like to annoy people who might be a little twitchy
d. you are in the wrong channel
answers to make you feel better
a. this is still a bargain, risk/reward is very favourable IMHO, out an order in and enjoy
b. not sure enough people on the BB respect your number to make any move happen
c. fair enough, but not sure enough people will roll in the s*** with you. That said it took you 1 min, so enjoy if you can. Do me a favour, come up with some original insults, cos the one on here are a little staid, boring, old, unfunny. Let me know if you want to play, happy to oblige.
d. it's ok, you're not the first