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I think we can rely on your statement - 'Liz is preparing for a massive U turn'.

Only one more ????

Afterthought - it's quite possible that a 3rd party expressing some interest in something Scancell might during initial discussions, have suggested that to deal with Stifel might be preferable ? IME this sort of thing does happen.

Three possibilities - 1. it's meaningless. 2. Scancell are consciously gearing up. 3. as above.

All good fun . . . .

Bermuda I've just twigged Nomad !

'Advisors' on the Scancell website prior to this RNS are :-

"Nominated advisor and Broker:
Panmure Gordon and Co
One New Change
London
EC4M 9AF

Joint Broker:
Stifel Nicolaus Europe Limited
150 Cheapside
London
EC2V 6ET "

So with this RNS, Stifel Europe have 100% replaced PG as the 'Nominated Advisor'.

Whilst Stifel and PG are joint brokers.

The change to Stifel as 'Nomad' could indeed have significance - it's been done for a reason. Maybe Stifel have come across some interest and it makes sense for that reason. Who knows ? It probably makes sense anyway as Stifel are 'top 2 mid sector M & A'.

Interesting and certainly better than nothing today. GLA

FTSE - never enough news is there ? But there's lot's going on.

Nice try - at least the SP is a little farther away now, than when you posted. Nice start - hope it lasts . . .

Ruck nice one - 800 years ! Scancell will smash that one . . . 2010 and David Evans - those were the days . . . I wonder how NXC is ?

That's right Ray. It's stunning that this paper references 120 other papers each with many contributors - obviously thousands of medical Scientists are on board this line of science - surely there must be plenty of Pharma around the World watching this.

SS17 you are right that Rome wasn't finished in a day - but it WAS finished. So roll on that Scancell day.

Bermuda thanks.

IF Covidity works, one less competitor now ?

https://www.reuters.com/business/healthcare-pharmaceuticals/astrazenecas-covid-vaccine-suffers-setback-nasal-spray-trial-2022-10-10/

C11 - news of Scancell seems like the needle in the haystack atm but you did it ! Thanks.
Let's hope SCIB1 helps the trial participants. ATB

Ciaskin thanks - 7 locations now and 5 recruiting. Bermuda, if news arrives in 2022 as predicted, that would be extremely handy.

Ruck the Inan 'prediction' was 1/2/3/4 months - as ever, no need for the sarcasm.

Much earlier today, Inan posted a list of positives, some very speculative but all good fun :-

""Opening spread still cheap ...
expected RNS over the 1/2/3/4 months
expansion of Modi1 .... full steam ahead
immunogenicity modi1
efficacy of modi1 initial readout
manufacture modi2
manufacture Iscib1
possible deal with Seagen
Readout of Scov 1 - Scov 2
Update on SCIB1 trial
First patient modi1 CR ... blood taken and sampled TCR deal with Biontech ******
other Glymab and Avidmab deals announced
Continued expansion of Lab capacity
AGM Date
accounts .....""

and

""one other point if we see efficacy at this stage with Modi1
it's being done without a Ci
serious big tick.... tock""

Life on Earth then ? ATB

Thanks Max P. She certainly doesn't look 65 !

Morning Ivy - what a lovely pic of our Prof. She looks well indeed - I wondered how old she is ?

Plus good news of the SCIB1 trial plus a blue week !

Thanks Johnny/RP. Excellent insights on which to finish a blue week.

China struggles with Covid continue - "China reported a total of 273 news cases as of Wednesday morning. The flare ups have spread to 27 provinces, according to state media. The recent rise in infections, which coincides with a national holiday, has prompted fears that tough Covid curbs could be implemented more widely before the party congress to avoid political embarrassment for Xi.

Many areas nationwide have moved to step-up measures amid recent Covid outbreaks with residents banned from leaving Xinjiang on Wednesday just weeks after the region began relaxing restrictions following an extended lockdown. The region - home to 22 million people - reported 38 new asymptomatic Covid cases on Tuesday. At the airport in Urumqi, the regional capital, 97 per cent of departing flights and 95 per cent of arriving flights were cancelled on Wednesday. All outbound trains and buses are also set to be suspended until further notice. It is thought that hundreds of citizens who travelled for the national holiday could be stranded by the new restrictions." https://www.telegraph.co.uk/world-news/2022/10/05/angry-tourists-confront-armed-guards-chinese-airport-placed/

Come on Covidity . . . . .

Thanks Ray/Bermuda. I remember talk of 'Boston' before. I wonder if that's Scancell's first visit ?

Hi WTP. Best to ignore RW who needs to get a life frankly. Here's the post from Marcus :-

"Seagen is 5.77% of Redmile`s portfolio, $ 151.11M. SEA-CD40 is a CD40 agonist and recently entered phase 2 clinical trial. The Fc-engineered AvidiMab® technology was introduced into SEA-CD40 in an IgG1 format to improve it functional and cytototic capabilities in cancer

Seagen’s SEA-CD40 is a nonfucosylated CD40 agonist MAb, and phase 1 data just unveiled at the Asco-GI meeting show 44% overall response.

Avidimab, improved functional affinity,superior B cell proliferative capability."

Marcus 419 on POG thread. Thanks Marcus.

Johnny thanks for yours yesterday. Excellent links. I copied it over there. ATB

It's quiet here as we drift along, waiting for a puff of news. But at least the week is in blue atm.

Hello Ruck. I'm back in Th. atm and Covid drags on here too. Of course it would be great if Covid would disappear altogether but as it is, IMO Covidity still has prospects - IF it works . . .

Hope you and yours are well.

Some covid 'experts' here, holding forth in the Daily Mail. FWIW I'm not getting alarmed, yet, but it's useful to see the Stats. https://www.dailymail.co.uk/news/article-11272999/Experts-warn-UK-start-devastating-Covid-wave.html

Covidity where are you ?