Member Info for Prion25

I agree John but our fellow posters are doubtful

Thanks Martinski
A Financier on the FT
Nothing on The 24hr News Upstaged by strictly and Dom Cummings
She stole Matt H's thunder then ?

who mentioned it Matt ?

might be worth watching "the papers" at 11:30 bbc 24hour news

Helen
Good find and somewhat disturbing setback in the fight against the virus .Its a real opportunity for RM to proclaim his therapeutic and its efficacy in treating not only Covid moreover its mutants as well if vaccine specific immunity against mutation is found to be ineffective .Now that's what I call a shot in the arm ! Perhaps he needs also to find a spin doctor to get the message through before we get forgotten

Badsterman
That question as been asked many times and its still a mystery to me to the point I wish I never invested out of frustration but the science was so compelling and its a life saving treatment. I am still here waiting to see it benefit those who need it

Moderma will require -70/-80c ? The Ice Age Cometh ?

org
I was thinking the same but he has to prepare on the assumption that the vaccine will be approved , on the other hand the MHRA doctor was adamant and very reassuring that all safety precautions will be scrutinised and then passed to some other commission for further checks and when you consider the final P3 for the vaccine will not finish till June 2021 and furthermore she said she is not prepared to rush I think it going to longer for approval than people might expect imv

duster
vaccinating 90 % of the healthy pop(who do not really need it ) is to reduce transmission and there again they still do not know if those people will stop shedding this confounding virus or how long its will protection will last .You are correct 10% of the vulnerable people who will need SNG if the vaccine is infective because of their impaired Beta interferon You could the vaccine may not protect those who it was meant to protect.

No reporter mentioned the threat of the virus mutations at the Downing street briefing .That would have been interesting

As RM said a broad spectrum therapeutic even benefit immunocompromised cancer patient on chemo with respiratory infections

Schrow123
just to complete your fine analysis Emerging Mutant strain eg mink are a growing threat to vaccine development but not to our therapeutic

more like -80 c no higher to avoid denaturing the spike mRNA into its mutant form at all costs otherwise you might wake in the morning looking like a hedgehog

more like -80 c

I am not anti vaccine .I will consider being jabbed with a first generation vaccine when it comes bur not this BioNtech vaccine Why ?
mRNA technology never been tested on humans other than human guinea pigs in the P3 trial
The guinea pigs will be under observation for the next 2 years for adverse effects etc in all ethnic groups
The technology mRNA was designed for primarily for cancer .Brilliant science but we don't yet how safe it is in the long term
We have a drug proven to be safe and no approval It will be interesting to see if they get emergency approval I will be surprised if they will get approval Perhaps others know more than I do

mumbo jumbo

More importantly there may have been more susceptible/Vulnerable individuals , elderly ,male , ethnicity, comorbidities etc within the placebo arm compared with the vaccine arm This we do not know the composition of each arm yet but seems like a big asked to compare like with like in a trial of 24.5 k individuals that why I think this information was released far too early But we will have to wait and see just hoping RM gives a reassurance RNS tomorrow !

The vaccine is good news and it was more than expected similar proclamation to SNG but it still it failed to work in 10% of individuals in the preliminary data . 10% of UK pop = possibility of 6million susceptible individuals then also take into account this percentage may be higher as we know from our research in the elderly , male, ethnicity, or susceptible individual with one of the 13 mutant genes (ref Casanova ) Of course it also depends on our hypothesis that impaired Beta interferon might be the reason that this virus is so lethal and not all vaccines will elicit a beta interferon response .This is where our therapeutic will be most beneficial And of the susceptible 6million subjected to an infectivity rate estimate of say 1 in 500 per day of those 6 million susceptible individuals equates to a wide ranging guesstimate of 12000 cases which may require our treatment coupled COPD and and cases throughout the rest of the world. These are few of my thoughts but the market will certainly not take notice of me but I hope RM sends a RNS to reassure us we are still very much in the game regardless of the vaccine GLA

The antigen test will always detect SARS CoVid 2 and its mutant variant strains but will not tell which mutant variant is present that will require further sophisticated testing .......that's my understanding

Thanks JD
Spot on with the detail

Mink carcases after skinning were going into the rendering process to for eventual products like bone meal ,meat meal (pet food ?), fat for synthetic diesel and even cosmetics I know we are talking about a virus and it may not survive processing unlike BSE. But its still potential to spread the virus .Animal rights activists are more dangerous by liberating the mink out of captivity and affecting all other species .