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Wonder if they'll get answered? No chance.
Certainly they get read by him so that he feels like a twat - chuckle.
Why was the retail appetite for supporting the business (as demonstrated by the oversubscription at 95p) not used for the raise rather than the HUGE discount given to scumbags that openly admit on podcasts hosted by clout chasing morons like Paul Hill that they're only investing for a fast buck?
What changed from the arrogance of 'don't worry about that - chuckle' to shafting all existing shareholders?
Why has the ava6k strategy changed over the course of a few weeks between the December presentation and the Turner Pope note shown to the 'investors'? Why has phase 1b re-emerged under a different name?
When will the CEO step aside so that someone with some commercial and strategic ability can ensure the future success of this business rather than the lifestyle CEO who's only talent seems to be kicking the can down the road whilst making calamitous naive embarrassing harmful decisions?
Nope. It’s the same as the 3 week. They’ll recruit wherever and move on when approved. It’s faster as they can dose patients in parallel. The time it takes will depend on recruitment, the safety committee and the bravery/health of patients.
Thanks for sharing. They recommend dose expansion for different dose levels. It all makes sense. It was interesting to see how many drugs had been approved and subsequently been found to be too toxic. All potential candidates for the platform. Great to see something genuinely useful and interesting shared.
What a day! I shared how to melt ice, now this.
That’s a coincidence. I asked and also got a response:
‘Are you f&@cking thick? For once we made it really clear so that even dunces could understand yet you’re still asking? No wonder I hate PIs so much. Anyway, must dash, I’m off to cash converters to thrash out the next financing deal’
Common sense really, there’s a limited amount of time it circulates so flinging in a ton won’t result in a better outcome than a steady stream. Apologies for the overly technical language. Perhaps I should go for an analogy as that’s what his lordship would do. Imagine a block of ice sat on a suspended wireframe. You could get a gallon of boiling water and drop that on top. It would splash and not have much of an impact, but you could pour the same volume at a lower temperature at a steady pace for longer and the constant contact of warm water would melt the ice. I’m available to present a poster if Chris can’t make it.
Key sentences to shut down the inevitable tedious cancer is cured green box FUD:
‘when brigatinib stops working, doctors have said there is another targeted drug she can take before requiring radiotherapy and chemotherapy’
When. Not if. Before requiring. Nothing is being cured here. What eventually happens… chemo. What’s better than chemo. Chemo without side effects.
‘ has a list price of more than £5,000 a month’
Two ways of looking at that. AVA6k could be cheaper and preferred for economic reasons. Or…. They can command a high price and it will be paid.
‘chemotherapy is tough - it makes people tired, and can cause nausea and hair loss’
This no longer has to be the case. Without the side effects, and given that’s the eventual treatment, you’d choose AVA6k as these expensive treatments become a waste of money. Why bother with an ineffective treatment that extends life with no side effects, when you can have an effective treatment without side effects.
The data shows ‘it works’ (tm). Dox will be dox. They’ve already proven they can deliver dox safely. There is further to go to get it to market, but saying it works when it has approval is rollocks. To state the obvious.