Member Info for PL75

We’ve had it then. He was last seen trying the 2 LFD solution by shoving one up each nostril. Wibble.

Ugh, I can’t stand cross ramping. Especially for underpriced companies that will at least double from where they are due to expanding their capacity to 3m and having contracts with the govt for their sovereign test (whoever that is) and coincidentally also a contract with Abakta who are producing the same (allegedly) game changing 100% sensitive test

Julia is going to be upset

Correct and we disagree. Your argument against using a confirmatory LFD (as in that case why bother with the original LFD) also stands for confirmatory PCR testing.

Luckily, myself, Wiggly and Mina are happy with our cheaper, more convenient solution.

*wanging on

Ok, I’m saying bother to reduce the burden and stop Deeks wanting on about false positives and people needing to isolate. They’re both valid solutions, one cheaper and more convenient

What’s difficult to understand?

Currently - use an LFD. Negative, crack on. Positive, get a PCR
Future? - use an AffiDx LFD. Negative, crack on. Positive, get a confirmatory LFD

By your argument CO, let’s all get PCR tests, why bother with AffiDx?

Nope, perfect aligned wires. That’s not true, the innova test is only to confirm positives.

CO, I disagree with needing a PCR if you get a negative on a second LFD. If it’s 100% specific it should be trusted. Either replace PCR with an LFD and trust it or don’t bother.

You keep saying sensitive. It’s irrelevant for confirming positives.

You have a 100% sensitive green light test. It’s called affidx, if you’re negative you’re 100% confident you’re negative so you’re green to go. It’s 99.x% specific so there’s a chance you might be a false positive....

You get a positive result. You need a red light test to determine if you should isolate. To confirm you use an LFD that’s 100% specific, possibly innova. If you’re then negative you can be confident you’re negative, if you’re positive you get a PCR for variant tracking. You should isolate as the chances of two false positives are minuscule as you’ve taken a 1 in 1000+ and a 1 in 10000 test.

That’s all I’ve got, I can’t explain it for a fourth time.

You've just mentioned sensitivity again. The chances of being positive on 2 tests that target different proteins and if both have specificity of 1 in 1000 to 1 in 10000 then yes, I'd absolutely trust it. The sensitivity is to confirm you are negative, so you're not ruining anything. If you're negative on an AffiDx then you're 100% not infectious. If you're positive, you need confirmation, so why not use another LFD? If anything it's a better option than PCR as that can give you a false 'positive' at a high Ct that is just residual virus.

Why? Specificity is what is important for verifying positives. If the most convenient and fast way that avoids isolation is another LFD rather than needing to book a PCR test then why not?

It’s up to the govt and MHRA to sort themselves out. Innova is currently a red light test. We now need the green light test approved and out there. Although, if we’ve already sold everything in to Europe...

You're right, and that's the beauty of a 100% sensitive test. The complication is from Deeks et al who pipe up if it's not 100% specific when there is low prevalence as it's impossible to have confidence in positive results. You then get the media banging on about people isolating for no reason due to inaccurate LFDs. This solves that problem. Not that there's much of a problem as PCR confirmation is already recommended, but that doesn't stop ol' testicle face.

You don’t take them both all the time though CO. You take your daily green light test. It’s 100% sensitive so if it’s negative you’re 100% confident you’re safe. If it’s positive, you confirm it with the 100% specific test. If at that point you’re still positive then go get your PCR test. If not, you’re ok to go about your business, but only in a cautiously optimistic way

No, you’re not leading the way, I’ve already suggested it except I said they should use up the innova tests for it as they’re pretty much 100% specific and target the n protein. Ours is the green light test - the good guy and the Innova test is the bad guy red light test.

Tsales, if you want to see desperate, have a good laugh at the odx Twitter pump and dump account #ShouldWeReallyTrustColin

Because they’re ‘are we there yet’ kids. Crying, bleating, moaning on here makes zero difference to Julie.

Zabadoo, he said in the ‘coming days’ which translates to ‘it’ll turn up when it turns up’. How has that been missed, you clown

Nice one Tony, can you point me to a ‘deadline’? You do realise that everything has been done and it’s purely a waiting game? It’s a bit late in the day to be getting all het up and frustrated. We’ve got a test and it’s really good. Relax a bit.

Julie has lost her rubber stamp, but as soon as she gets a new one from Amazon we’ll get the go ahead. Julie hasn’t got prime, the silly mare, it’ll arrive some time in the coming days.

The doc on the Beeb said similar, that there are super spreaders. As you’ve said, interesting that everyone has this potential, especially given they’re equally likely to be asymptomatic.