RE: Dose response relationship is complex1 Nov 2025 23:03
People talk of complete unknown dose escalation outcomes without knowing pre clinicals are incredible insights into what the HEMO expect.
The DSMB will have requested and seen the pre clinical results that lay the foundations as to what Vladik expects to see in humans. This data is material. It sets standards, gives indications of future outcomes. The translation between humanized mice to humans is likely to be not such a huge leap.
HG CT 1 is next gen. Technically next next gen (3rd gen). The amount they've learnt from previous developments, the mechanics introduced to mitigate previous risks, specific vectors, its pretty much mind blowing.
So without trying to drone on, the nay sayers, imo, don't really understand any of it. Any of what makes HEMO special. So sit safe investors. The magic of HEMO is growing every day. And it will all be revealed soon enough.