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Not an expert in markets, just a private dabble, so I don't post often and so usually don't comment. But I am a medical researcher so can point out mistakes on medical grounds when I see them. On that note, let me correct a few thibgs for you watcher.
1. The oxford/astra vaccine was not an mRNA vaccine. It used a common cold viral vector to deliver the spike protein (essentially take common code, remove the part that makes it infectious, then add instructions to make spike protein).
2. Inactivated viruses are not used much anymore as they produce a significantly poorer immune response than live viruses, which is why viral vectors, like astra, have been the preferred choice for a while.
3. mRNA vaccines are vaccines and not gene therapies. They cannot tell your body to "up-regulate production of spike proteins" as that implies human cells produce the covid spike proteins normally, which they do not. They also do not modify your genes as the mRNA is translated in the cytoplasm of the cell, not the nucleus where genes (DNA) is stored. Even if they did penetrate the nucleus, without a reverse transcriptase (which is not in vaccines) the mRNA would have no way of incorporating into DNA as is made of different materials (niteably uracil replaces thymine).
4. Blood clotting was a more severe side effect with astra then mRNA vaxes. mRNA vaccines had higher risk of heart inflammation in young makes, but lower (though non zero) blood clot risk.
5. In UK alone, current infection rates with vaccine are highest since pandemic began, yet deaths are lower than previous waves precisely because vaccines have not "done more harm than good" (paraphrased).
6 moderna may pay us gov money, but Oxford was backed by UK gov, so why would we pull it here to give moderna a run for a conspiracy in the states? This annoys me personally as people assume huge profit margins in states are same world over and they aren't. As noted, astra was offered at cost.
6. Pfizer did not have the cure "ready to go" and patented as you suggest. The viral genome was sequenced rapidly (very easy to do) and at that point the spike protein sequence was widely available, which is why astra, Pfizer, Moderna and J&J all used it.
7. Finally, you say you worked in oharna for 20 years. Without doubting that, I'd like to poo t out vaccine development and drug development are very different processes and you have made some basic mistakes in your understanding of vaccine technology here, so perhaps a friendly caution that applies to me and everyone else too: even if you are an expert in one field, be careful of over generalising your knowledge to other fields as it doesn't always transfer.
Have a good day all and good luck on our holdings.
Weird you'd tell us this midnight on Sunday when you presumably "cut your loses" during regular trading in Friday. But if your genuine sorry about your loss, we've all been there and it's gutting. Not sure much has changed recently to make now a moment to be particularly worried. Court case came out months ago and appeal decision probably months away at least so uncomfortable as it is, I personally don't see any point doing much with these except holding now. If I was gonna sell it would have been sooner, but not in middle of wider market drop due to war in Ukraine. To each his own though and dyor, obviously. Good luck for all LTHs.
Dam it, started a new job this week after 5 months unemployed and so missed all this! Would have chosen giantsquid or his famous "." topics... Oh well, still would have been eaten by some of u lovely people.
Fair enough, though the drops on those shares probably had more to do with invasion of Ukraine than response to results. Hopefully when Ukraine situation resolves, their values will rerate accordingly.
In fact, if you knew the company would be suspended, there was never a risk of them profiting from blood money. They would just be losing money.
The sanction is not a matter of morality but a matter of politics. Whether you were right on point of morality or not I am not commenting on, but you weren't arguing investors would be out of pocket when dividend cancelled and stocks suspended, you were arguing its immoral to profit that way.
Hi all, so this one has joined polymetals as close only on trading 212. Guessing from messages the rest of you can still buy so can anyone recommend a good broker to use? Have my ISA for the year still to use, just not sure where will still let me buy at a low fee.
My wife and I both odeon unlimited members (no cine worlds near me unfortunately. Went to one in Eastbourne and blew us away, just shame not got one local). Convinced couple of friends and family to join too, so we go once or twice a month now. Nothing quite like the experience of cinema for seeing a film. Saw dune at Christmas with a friend and was just out of this world!
Trading 212 added message that poly will not be tradeable on their platform after tomorrow, but no such message for evraz. If other platforms are similar, may explain different outcomes?
Gotcha, thanks knowbodyyouknow, didn't know what global OTC was!
And yeah no such warning on EVR yrabsmurruc, so some good news there. Not that it'll make a difference as my plan for all 3 is to leave them til sanctions stop and see where they lie (hopefully significantly up from here!).
Openeyes, just passing in what trading 212 told me, not making assumptions, don't understand it enough to maybe, which is why I asked.
"Russian Securities - Suspended from trading
Due to the ongoing situation in Ukraine, the below listed Russian securities have been suspended from trading by their respective market exchanges.
LSE traded securities
MD MEDICAL GROUP IN-GDR REGS - MDMG
LENTA PLC - LNTA
HMS GROUP PLC - GDR REG S - HMSG
GAZPROM PJSC-SPON ADR - OGZD
EN+ GROUP INTERNA- GDR REG S - ENPL
PETROPAVLOVSK PLC - POG
X 5 RETAIL GROUP NV-REGS GDR - FIVE
GLOBALTRA-SPONS GDR REG S - GLTR
ROSNEFT OIL CO PJSC-REGS GDR - ROSN
O'KEY GROUP SA-GDR REGS - OKEY
VK CO LTD - VKCO
ETALON GROUP-GDR REG S - ETLN
ROS AGRO PLC- GDR REG S - AGRO
POLYMETAL INTERNATIONAL PLC - POLY
Xetra traded securities
GAZPROM PJSC-SPON ADR - GAZ
NASDAQ & NYSE traded securities
HEADHUNTER GROUP PLC - HHR
OZON HOLDINGS PLC - OZON
YANDEX NV - YNDX
MECHEL PJSC-SPONSORED ADR - MTL
CIAN PLC - CIAN
MECHEL-PREF SPON ADR - MTL PR
MOBILE TELESYSTEMS PUBLIC JO - MBT
OTC traded securities
Polymetal International PLC - AUCOY
MMC Norilsk Nickel PJSC - NILSY
LUKOIL PJSC - LUKOY
Polyus PJSC - OPYGY
Gazprom Neft PJSC - GZPFY
Rostelecom PJSC - ROSYY
* Global OTC will suspend trading in the above instruments effective at the close of trading on the 4th of March, 2022. If you hold any of these instruments past this date, you will not be able to close your position."
Russian Securities - Suspended from trading
Due to the ongoing situation in Ukraine, the below listed Russian securities have been suspended from trading by their respective market exchanges.
LSE traded securities
MD MEDICAL GROUP IN-GDR REGS - MDMG
LENTA PLC - LNTA
HMS GROUP PLC - GDR REG S - HMSG
GAZPROM PJSC-SPON ADR - OGZD
EN+ GROUP INTERNA- GDR REG S - ENPL
PETROPAVLOVSK PLC - POG
X 5 RETAIL GROUP NV-REGS GDR - FIVE
GLOBALTRA-SPONS GDR REG S - GLTR
ROSNEFT OIL CO PJSC-REGS GDR - ROSN
O'KEY GROUP SA-GDR REGS - OKEY
VK CO LTD - VKCO
ETALON GROUP-GDR REG S - ETLN
ROS AGRO PLC- GDR REG S - AGRO
POLYMETAL INTERNATIONAL PLC - POLY
Xetra traded securities
GAZPROM PJSC-SPON ADR - GAZ
NASDAQ & NYSE traded securities
HEADHUNTER GROUP PLC - HHR
OZON HOLDINGS PLC - OZON
YANDEX NV - YNDX
MECHEL PJSC-SPONSORED ADR - MTL
CIAN PLC - CIAN
MECHEL-PREF SPON ADR - MTL PR
MOBILE TELESYSTEMS PUBLIC JO - MBT
OTC traded securities
Polymetal International PLC - AUCOY
MMC Norilsk Nickel PJSC - NILSY
LUKOIL PJSC - LUKOY
Polyus PJSC - OPYGY
Gazprom Neft PJSC - GZPFY
Rostelecom PJSC - ROSYY
* Global OTC will suspend trading in the above instruments effective at the close of trading on the 4th of March, 2022. If you hold any of these instruments past this date, you will not be able to close your position.
Thanks CWWX, much appreciated.
Trading 212 saying poly stock (and Ros Agro which I'm also in) will be suspended from tomorrow (4th march) so will not be able to close position after that. Only have a grand in it so tempted to let it ride and hope when unsuspended I will be able to sell at a nice profit. Does anyone know if this is how it works though? I assume if I cannot close my position, I therefore still have the position i.e. I still own the shares right?
Thanks for this HNS. So there was no break fee in the contract? I guess that's why they didn't just pay the exit fee and move on!
Sorry for slow reply: didn't check in on board yesterday. Just to say tha
Nks @shazabo! I get stuck behind ft pay wall a lot so nice of u to copy and paste it.
Apologies for the horrendous English and typos: autocorrect on phone a tad over zealous it seems, lol
As for the media, the mainstream definitely whips up a frenzy over little things (and I hate it) but on the flip side, alternative media often undersells the risks, manipulates the statistics to see what they want and aren't fact checked. This goes for so called you tube experts too (the guy in this video is a doctor of education and former nurse, not a medical doctor, statistician or epidemiologist). I get why people want to use alternative media when the establishment can be so intrustworthy, and I'm not knocking people for not being able to do the research themselves directly (I struggle when outside my own expertise as well and I do it for a living!) but I'm just saying everyone had an agenda, not just mainstream.
Not a clap back, just correcting some bad stats with more accurate ones. Anyway, I'm off to work so enjoy your day all!
Hey kick,
You haven't missed any, haven't really post much as though I read the board, not for much of value to say on sticks, lol.
You're right the pandemic seems to be coming to an end, and thank f**k for that! Looking forward to my cine shares going up and my stress levels back down. Plus hopefully some research funding will start heading back to cancer research so I can get a longer term contract rather than to covid, hahaha.
As for the data, the "average age of death" is covid being 82.5 is on fact not just disputable, its false that is the average life expectancy for a male in UK average over last 3 years. Depending if u use mean or median, and if you look at males or female s, average age of covid death ranges from 78.6 (mean male age) to 85 (female median age). https://www.ons.gov.uk/aboutus/transparencyandgovernance/freedomofinformationfoi/averageageofthosewhohaddiedwithcovid19
Secondly, just because the disease is more deadly to the elderly, doesn't mean it cannot affect the young. Indeed, due to higher vaccine uptake in the vulnerable groups, around 1 in 4 covid deaths were in under 65s in the Omicron wave. https://amp.theguardian.com/world/2022/jan/16/what-do-we-know-about-people-who-died-covid-uk
Thirdly, as for myocarditis and pericarditis, there isn't a"large number" of people getting it. This is hype by the media and you tube "experts". Israel, with the highest level of surveillance of the population as was agreed for them getting advanced access to the vaccine, vaccinated around 5 million people and reported under 200 cases. That's an increase of 1 in 25000, or 0.004%. Compared with several studies of US athletes who caught actual covid, where they found an increased incidence of carditis of 0.31-3%. So even with the heart issue, the risk is higher from catching covid than from getting the vaccine. https://www.gov.uk/government/publications/covid-19-vaccination-myocarditis-and-pericarditis-information-for-healthcare-professionals/information-for-healthcare-professionals-on-myocarditis-and-pericarditis-following-covid-19-vaccination
And all of this overlooks the effects of long covid in young people. My sister is young and active, but since catching covid she's become allergic to several foods so severely she now needs and epipen for when she eats out and has been to A and E 3 times while waiting for an allergy panel. She had no allergies or history of anaphylaxis before and this has been brought on by her infection. But people like this, and the life changing results (she's also struggling to pass her fitness test for work, 1 year on from recovery, as lung function isn't back to full yet) aren't factored in when you only ask average age at death. There isn't a "long vaccine" however, as vaccine side effects all seem to resolve within days to weeks (for myocarditis).