RE: Trusted News Initiative5 Apr 2022 14:28
Not an expert in markets, just a private dabble, so I don't post often and so usually don't comment. But I am a medical researcher so can point out mistakes on medical grounds when I see them. On that note, let me correct a few thibgs for you watcher.
1. The oxford/astra vaccine was not an mRNA vaccine. It used a common cold viral vector to deliver the spike protein (essentially take common code, remove the part that makes it infectious, then add instructions to make spike protein).
2. Inactivated viruses are not used much anymore as they produce a significantly poorer immune response than live viruses, which is why viral vectors, like astra, have been the preferred choice for a while.
3. mRNA vaccines are vaccines and not gene therapies. They cannot tell your body to "up-regulate production of spike proteins" as that implies human cells produce the covid spike proteins normally, which they do not. They also do not modify your genes as the mRNA is translated in the cytoplasm of the cell, not the nucleus where genes (DNA) is stored. Even if they did penetrate the nucleus, without a reverse transcriptase (which is not in vaccines) the mRNA would have no way of incorporating into DNA as is made of different materials (niteably uracil replaces thymine).
4. Blood clotting was a more severe side effect with astra then mRNA vaxes. mRNA vaccines had higher risk of heart inflammation in young makes, but lower (though non zero) blood clot risk.
5. In UK alone, current infection rates with vaccine are highest since pandemic began, yet deaths are lower than previous waves precisely because vaccines have not "done more harm than good" (paraphrased).
6 moderna may pay us gov money, but Oxford was backed by UK gov, so why would we pull it here to give moderna a run for a conspiracy in the states? This annoys me personally as people assume huge profit margins in states are same world over and they aren't. As noted, astra was offered at cost.
6. Pfizer did not have the cure "ready to go" and patented as you suggest. The viral genome was sequenced rapidly (very easy to do) and at that point the spike protein sequence was widely available, which is why astra, Pfizer, Moderna and J&J all used it.
7. Finally, you say you worked in oharna for 20 years. Without doubting that, I'd like to poo t out vaccine development and drug development are very different processes and you have made some basic mistakes in your understanding of vaccine technology here, so perhaps a friendly caution that applies to me and everyone else too: even if you are an expert in one field, be careful of over generalising your knowledge to other fields as it doesn't always transfer.
Have a good day all and good luck on our holdings.