Member Info for NoonRiser

On the bounce There may be money to be made today.

Yesm8, that's it really. To us it is money, and I feel as bad as the rest out there, but to many PD sufferers, I think this was hope for the future. Really sad, let's hope PYM carry on with the research.

...those with PD. Well done to PYM though, they have put a lot of time and effort into this. I wish them every future success.

You had to say that didn't you ! NVTA were my second largest holding. I put £18k in there when Eric Kohn took over, again believing that the company was a good recovery prospect. Did all the research etc, but (again) was let down by a poor BoD. Likewise with ANGM, VOG and SOLG. I really can pick 'em.

Yes, i agree. Keeping the SP cool does pay off when they eventually let it go.

9.98p / 10.19p Keep it warm guys !

...2 x 250K buys @ 10p from yesterday not showing, Now why would they do that ?

...9.75p / 10.25p Let's see how that pans out !

I'm no expert, but have been in here (on & off) for 5 years or so. I posted my thoughts at 9.11 this morning if you're interested.

...tick tock...

All buys, bar 1. PYM always moves at a more sedate pace, but that buying pressure keeps building and building ! A lot will be watching and trying to pick an entry point, many will leave it too late.

Yes, it can get a bit 'Spikey' on here at times. A lot of day traders watch PYM as they know that if good news comes, everybody wants to get in. They usually buy late as they don't like tying funds up, so don't always get the best price. I note that the rise here has started early, so maybe the lessons have been learned. I wouldn't expect any retrace from where we are now as buying pressure is increasing.

Well done m8, I've just managed another 47K (shares, not cash!) as I really believe in this company. it's all buys today which is always a good thing with PYM. Good news always seems to be preceded by a flurry of small buying.

I rarely speculate on what will happen to an SP as I don't agree with ramping (or de-ramping for that matter). That said, if these trial results are positive, it opens the door to a massive transformation for PYM as Cogane could be the most beneficial new drug for many years. Read through the notes posted earlier and it will give you an idea. Probably the best way to answer your question though would be to say that I expect the SP will probably reach around 20p or higher initially, and will then depend on further developments. The company have invested a lot of time, effort and cash into getting where they are now, that won't be given away cheaply. Any major wishing to buy Cogane will need to pay a very fair price, if the trial results are linked to a deal for the future, well it would be Hi Fives and Whoopee Doo's all round ! That's assuming of course that the trial is a success, which WE don't know for sure.

...buys coming in @ 9.95p. tick tock....

...company are confident enough to seek (and gain) orphan drug status, they must be reasonably certain of the trial results.

During the period · The last patient completed participation in the CONFIDENT-PD Phase II clinical trial of Cogane™ in untreated patients with early-stage Parkinson's disease in December 2012. Results from this trial remain on track to be available in February 2013. · Further work is ongoing with a number of leading opinion leaders and charities with an interest in Cogane™ in Amyotrophic Lateral Sclerosis ("ALS") to design a clinical development plan. Provisional indications for financial and logistical support for future studies of Cogane™ as a treatment for ALS have been received. · A meeting has been held with the US Food and Drug Administration ("FDA") at which a clinical development plan for Cogane™ in ALS was agreed. Cogane™ for ALS has been granted Orphan Drug status which offers the potential for accelerated development compared with conventional drug development programs. · A Phase I study of new solid dose formulations of Cogane™ was initiated and results are expected in Q1 2013. · Our financial performance from 1 October 2012 to date continues to be in line with our expectations. Based on our current expectations Phytopharm is financed until at least the end of Q1 2014. Mr Tim Sharpington, CEO commented: "Whilst completing the CONFIDENT-PD clinical trial in Parkinson's disease the Company has been planning for the next stage of development. We have been pleased to receive the support of leading opinion leaders and charities for our development plans for Cogane™ in ALS, which we believe can add value alongside our work in Parkinson's disease. We have also had discussions with the FDA and potential pharmaceutical partners about how best to complete the development and commercialisation of Cogane™. The results from the CONFIDENT-PD clinical trial will be important in determining how our future strategy evolves and we look forward to receiving these results shortly". Cogane™ in Parkinson's disease Parkinson's disease is a movement disorder characterised by muscle rigidity, tremor and a slowing of physical movement (bradykinesia) and, in extreme cases, a loss of physical movement (akinesia). The primary symptoms are the result of altered signalling in an area of the brain, the striatum, responsible for the control of movement. This is caused by degeneration of dopaminergic neurones that project from the substantia nigra to the striatum, leading to insufficient formation and action of dopamine. Parkinson's disease is therefore termed a neurodegenerative disease. The disease is slow in onset and the appearance of symptoms reflects the gradual loss of dopaminergic neurones. Progress to date Cogane™ in Parkinson's disease - progress to date The preclinical neuroprotective profile of Cogane™ suggests that it will have benefit on both motor and non-motor symptoms of Parkinson

They sold around £23k 's worth, so hardly a deal breaker ! Maybe short of coffee money for the BoD's dining room.

...we don't get any of the idiot ramping on here in the lead up to the trial results.

...AGAIN ! 150k BUY not shown as a buy ! As good old Victor would have said, 'I don't believe it !'