Cold turkey?26 Mar 2022 10:37
This may be of interest; I was not previously aware of the importance of Russia and Ukraine in the bio supply chain:
https://cen.acs.org/pharmaceuticals/drug-discovery/War-Ukraine-knock-ons-drug/100/i11
"Russia’s invasion of Ukraine has upended lives, but it is also causing ripples in businesses far from the front line. Drug discovery, experts say, is about to get much trickier.
In 2018, Duncan B Judd of the consulting firm Awridian teamed up with researchers in Ukraine, Latvia, and France to survey the market for high-throughput screening compounds used in drug discovery (Drug Discov. Today 2019, DOI: 10.1016/j.drudis.2018.10.016). They concluded that companies in Ukraine and Russia like Enamine, Life Chemicals, and ChemDiv supply around 80% of the world’s screening compounds. “I’m not sure people realize the scale of the problem,” he now says. “It’s going to make a big impact.”
Jonathan Heal, who leads the in silico team at RxCelerate, a UK-based contract research organization (CRO), says these companies are an essential part of the drug discovery ecosystem. “When we saw that Ukraine have been invaded, we realized straightaway that this was going to create some problems,” he says.
To fulfill customer orders, Heal says, RxCelerate is managing to find only around 30% of the compounds previously available, and that’s with much extra effort."