RE: T CELLS off now on21 Nov 2025 20:22
Reminds me of Chrono-immunotherapy: In a large retrospective cohort (361 patients with metastatic or locally advanced solid tumours treated with ICIs such as pembrolizumab, nivolumab, atezolizumab, durvalumab or avelumab) at the Centre Léon Bérard in France, the authors found that infusions given before 11:37 AM were associated with significantly better overall survival than infusions given after that time. Patients whose majority of ICI infusions occurred before 11:37 had a median overall survival (OS) of 30.3 months, versus 15.9 months for those treated later.
ICIs = immune checkpoint inhibitors such as pembrolizumab, nivolumab, atezolizumab, durvalumab or avelumab. Something to bear in mind if you or a family member end up in the unfortunate need of such medication.