RE: French anyone27 Oct 2021 12:20
Don't speak French but this is a translation courtesy of Google
News
COVID-19: Phase III for a beta interferon to be inhaled at home
Research is advancing on new forms of COVID-19 treatment that are easy to follow at home. The AIDS Clinical Trials Group (ACTG) thus announces the passage of the experimental drug "SNG001", an inhaled formulation of beta interferon in a phase III clinical trial, within the framework of the research program "ACTIV-2", a supported program by the National Institute of Allergy and Infectious Diseases (NIAID / NIH).
ACTG is the world's largest HIV research network, but this program has recently expanded to include outpatient treatment evaluation for COVID-19. The phase III trial is to assess the effectiveness of an inhaled formulation of interferon beta in treating early symptomatic COVID-19 at home - or in out-of-hospital patients.
ACTIV-2 is the first trial to assess candidate SNG001, developed by Synairgen, a British university spin-off as an outpatient treatment for COVID-19. SNG001, a beta interferon - or natural cytokine promoting the antiviral response - is self-administered as a nebulized dose (15.6 MIU) taken once daily for 14 days. As part of the trial, the participants were trained in the use of the nebulizer by the researchers. 2 other treatments, BRII-196 / BRII-198 (a combined treatment with a monoclonal antibody) and SAB-185 (a new treatment with a polyclonal antibody) are also undergoing a phase III trial as part of the ACTIV- research program. 2.
Developing simple at-home treatment options
“This inhaled version of beta interferon expands possible treatment options for people with COVID-19 who are not hospitalized. If validated, such a treatment would simplify care for a large number of people with COVID-19 ”.
The phase III trial for SNG001 is to assess the safety and efficacy of the candidate in reducing the risk of hospitalization and death in non-hospitalized adults with mild to moderate forms of COVID-19. The study is being led by a team from the University of North Carolina and Stanford University.
An option that comes in addition to the antiviral pill from the Merck Laboratory in the process of "fast track" approval by the European Medicines Agency.