Possible reduction in the need to do large scale CTs for new Covid vaccines29 Jul 2021 19:48
Link: https://www.nature.com/articles/d41586-021-02096-3
A blood marker predicts who gets ‘breakthrough’ COVID
People fully vaccinated against COVID-19 are less likely to become infected with the coronavirus if they have relatively high levels of virus-blocking antibodies, according to a study of thousands of health-care workers who received the Pfizer–BioNTech jab1.
The analysis adds to a growing body of evidence that a person’s levels of ‘neutralizing’ antibodies, which block SARS-CoV-2 from infecting cells, predict whether that person will become infected.
A robust predictive marker, known as a correlate of protection, could help regulators to approve new vaccines without requiring large clinical trials. It could also help them to assess the need for booster shots to guard against emerging viral variants. The study “is an important step in further validating the use of neutralization titre as a correlate of protection”, says Miles Davenport, an immunologist at the University of New South Wales in Sydney, Australia.
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That's the most important bit for us I think. It would be great if Scancell could avoid the heavy overhead of costs to run yet another massive trial.
ATB, whether you are a Strong Hold for Scancell, a Buy, or a Seller! Enjoy the rollercoaster whilst you can.