RE: Thorn17 Jun 2025 12:44
'But the trial, in its entirety, you know Phase 2, the whole trial, was to prove that AVA6000 was better at treating STS than standard Dox.
Do you accept that?'
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No, I don't accept that. Where is your evidence that this started out as a trial to prove that AVA6000 was better at treating STS than standard Dox? For example, in the 2020 annual report released in mid 2021 this is the only mention of STS:
'Phase I study will be clinical proof-of-concept of the pre|CISION™ platform
The phase I study is a first-in-human, open-label, multi-centre study to be carried out in the UK in patients with locally advanced or metastatic solid tumours which are known to be FAP positive, including pancreatic, colorectal, breast, ovarian, bladder and non-small cell lung cancers, squamous cell carcinoma of the head and neck and soft-tissue sarcoma.'
Then Bill Tap got on board and STS became the focus, switching to SGC and TNBC more recently. It's fluid as they zero in on phase 2... it's simply not true that phase 2 was always about STS right from the start.