RE: Chimeric Bait Receptor16 Mar 2022 14:17
Very interesting, @JHFH - the cop/bait car thing was the first to pop into my head, too.
This caught my attention:
CBRs are made from parts of naturally occurring proteins/receptors and endow immune cells with the ability to destroy invading pathogens.
So no detail yet as to the mechanism employed - shame.
§ CBRs are modular synthetic receptors that can be reconfigured to attack almost any virus, bacteria or mammalian cells, including cancerous cells.
This sounds almost comically broad in scope of application. If he really has figured out a way to program/re-engineer immune cells as trojan horses, but in reverse, an immune cell 'kill box' (come on in, infect me, consume me - DEATH), that would be a big deal, especially across the proposed, wide range of application. As JHFH points out, many mammalian cells replicate slowly but viruses, bacteria, often much faster - he must have a mechanism identified that targets their ability to replicate, some novel form of transcription inhibition?, I don't know, but it must be a pathway that that has been hitherto overlooked to be patentable.
Typical Vlad, it's a possible, novel, bold, new branch. As always, the devil is in the detail of how this might be achieved - hence, I think, the muted market response; there's just not enough to hang your hat on, especially given recent events; how do you commit given his history of stupid, cryptic tweeting, diabolically inept financing.
Papers, peer review, robust data, all necessary/required to value. And that's before we all ponder - will it work without issue, in-man, with such ubiquity.
I'm excited, sounds spiffy, just need to see the detail on how it works (which he says will be forthcoming). Also, I would much rather he had given the Covid application much less prominence, we need to move up on solid development, not based on something that mires us into the 'Covid play' group. He gives it far too much prominence for my liking.