Member Info for D-Geeman

'Hi D, hope you and family are doing ok. '

Not too bad thanks CTSFO.

(Off-topic but the physio has told us of a case study, a man with FND. He was in a wheelchair for an extended period before they realised that, on ice, he retained the ability to skate perfectly. He'd learned ice skating as a child and the brain retained the skill more as a reflex. Off the ice again, he still couldn't walk..)

Hi CTSFO,

I've been googling and found this. Do you think that even if Dox (and presumably AVA6000 as AVA6k behaves like dox in the tumour we are lead to believe) could cause kidney damage then another drug along side AVA6k could help prevent that damage?

Highlights

•

Doxorubicin causes significant damage to both the glomeruli and tubules in kidney.

•

Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation.

•

Apigenin protected renal cells against doxorubicin toxicity without reducing the sensitivity of tumor cells to doxorubicin.

•

Apigenin may serve as a promising protective agent against chemotherapy drug-induced renal toxicity in cancer patients.

https://www.sciencedirect.com/science/article/pii/S0753332221000937#:~:text=tubules%20in%20kidney.-,Apigenin%20ameliorates%20doxorubicin%2Dinduced%20renal%20injury%20via%20inhibition%20of%20oxidative,of%20tumor%20cells%20to%20doxorubicin.

'one man one vote then...!!!'

I hope they let women vote..

Maybe TG could have a word with President Biden on knowing when the time to leave the stage is.

I thought it interesting that special designation drugs (often?) get full approval - bearing in mind that ava6k already has ODD status. And drugs may get multiple designations prior to full approval

I read this elsewhere (posted by Tyke 68) today but thought it interesting for AVCT too:

'the share of FDA-approved drugs receiving each of the five special designations and review programs over the past 20 years. Two-thirds of new drugs received at least one special designation. Out of 666 new drug approvals, 367 (55%) received priority review, 279 (42%) orphan designation, 215 (32%) fast track, 124 (29%Footnote 4) breakthrough therapy, and 103 (15%) accelerated approval. The share of drugs receiving the orphan designation increased from 20% in 2003 to 54% in 2022. Similarly, the breakthrough therapy designation gained in popularity after its introduction in 2012, with 12% of drugs receiving the designation in 2013 and 35% in 2022.'

https://link.springer.com/article/10.1007/s10198-023-01639-x#:~:text=Out%20of%20666%20new%20drug,2003%20to%2054%25%20in%202022.

ICE, did you catch that chap that BV posted about? It was interesting and, if true that big institutions use moving averages to time investments, possibly very relevant

'Windy on holiday to be fair 🤣🤣👍'

Yes ICE, I wonder what he'd say the next resistance point is? 54p / 58p? Then to 74p?

If we're lucky he's only gone for 10 days...

The SP on april 15th was around 51.5p so if they haven't already closed GSA won't have made very much.

Seems extraordinary that the SP is down as I type. I added a few more at the best price I've ever had.

Sooner or later the content of a business update will have to change.

Thanks BV I will take a look. Looks interesting from your paragraph.

I find this story quite interesting https://www.independent.co.uk/news/business/don-t-they-just-love-being-in-controls-1358096.html They got into controls by accident yet it became the core of the company. It's the management that makes or breaks a business. If CC has it in her then DX could still fly.

'Who is this Al character?'

WAG, I take it you're just being a bit of a wag?

'Anyway off to the Med for 2 weeks, '

Enjoy your hols Wyn!

I spent a couple of minutes and it didn't take long to see if I've misjudged Watching and his prediction and statements of 'fact'.

How do these past posts stack up?

––––––––––––––––

Watching2

Posted in: AVCT

Posts: 7,775

Price: 87.00

No Opinion RE: Resistance 90/95p26 Feb 2024 08:45

No funding required till 2025

Watching2

Posted in: AVCT

Posts: 7,775

Price: 85.50

No Opinion

RE: Potential fund raise23 Feb 2024 14:36

Lone 🤡 no placing required we have plenty cash atm.

Nice try tho 🤣

Watching2

Posted in: AVCT

Posts: 7,775

Price: 111.50

No Opinion

RE: Festive cheer22 Dec 2023 15:29

Definitely won’t. Be here next We will be . Sold

£20 plus per share

All done n dusted

Merry Christmas

Ps I’m already looking for a company to put a bit of profit into 😊

Watching2

Posted in: AVCT

Posts: 7,775

Price: 139.00

No Opinion

RE: TRADING28 Nov 2023 09:14

That has always been the case,

I Agree selling now would be bonkers

Gl x

'LFTs were never going to be effective ... All a waste of time'

Not how I remember it Bella.

I recall being able to travel abroad again after producing negative tests, and also missing a live show when I'd failed a test, a show where I would have been sat in amongst a large audience.

I think testing generally has a bright future if CC can get DX profitable, whatever she then does with it. History is full of entrepreneurs who buy loss making companies, turn them around and make a fortune (and full of loss making companies which have dragged down the parent company).

RE: Snippets13 Jun 2024 22:52

Last one - a post from Ivdeology about being a U.K. Responsible perso. Apparently they have 489 products registered with theMRHAand more joining weekly.

For AVCT investors on here, I noted that the Launch DX MD liked the post!

https://www.linkedin.com/posts/ivdeology-ltd_role-of-the-uk-responsible-person-and-the-activity-7207032517424525313-dbN1?utm_source=share&utm_medium=member_desktop

So “Incoming” was more from the Sujood school of forecasting that the Craig Williams' Academy of predicting the election date.

(Actually a rare Thursday for me with zero 7am RNSs across my portfolio.)

Thanks for posting that CTSFO. I had to remind myself that hertz is per second.

You’ve hinted at your work being to do with the circulation of blood in the human body. Maybe I’m being nosey but could you say more, only because I’m interested.

Atb, D

Hi Touk,

I think I wrote: 'We are all gamblers. Especially on aim.'

Even now if I sold everything in the portfolio, Avct, TLSA and half a dozen others, and put them into AZN I still wouldn't be certain of the outcome, but it would certainly be a much safer environment. It would be 'investing' by most people's definition but some uncertainty would remain.

Wyn, many thanks for thoughtful your reply earlier.