Member Info for D-Geeman

Hi Megan,

No, didn’t buy more but didn’t sell when they were higher either so all’s good :-)

It looked like TLSA were headed back down but management seem to want to keep the price up so let’s hope they succeed!

Atb, D

I'm also in HEMO and $TLSA and both have recently released news on dosing individual patients, and not just the first patient but subsequent ones. So it can't be difficult to communicate these things – and other things – when there's a will.

24 hrs is a 'long term hold' for you Watching. Glad we've sorted that out, you dark horse.

'Trading is definitely for me ! '

You can't deny that Watching2, having bought SEE, sold SEE (within 24 hrs) and then bought AVCT.

SEE now +12.45%

But: 'Yes. Geeman

But sold. And put profits here'

Poor Watching2, you only had to wait a couple of hours and you could've sold your SEE for another 4%.. Thats trading for you I guess, if you don't have luck on your side.

Tiziana Life Sciences Ltd.

NEW YORK, March 25, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announced dosing of new patients at Yale MS Center which is participating in our multicenter Phase 2 clinical trial evaluating intranasal foralumab for non-active Secondary Progressive Multiple Sclerosis (na-SPMS). Other centers are currently enrolling include Johns Hopkins, U Mass Medical Center and Brigham and Women’s Hospital.

This Phase 2 trial aims to assess the safety, tolerability, and foralumab’s effect on microglial activation in patients with na-SPMS. Intranasal foralumab offers a novel approach to potentially mitigate the progression of SPMS. This multicenter study is important because it combines brain PET imaging, immunology, and measures of clinical evidence accepted by FDA.

"We are pleased to announce dosing at Yale in our multicenter Phase 2 trial, marking an important milestone in our efforts to address the unmet medical needs of patients with non-active SPMS," said William Clementi, PharmD, Chief Development Officer of Tiziana Life Sciences. "This trial represents a significant milestone in our clinical development program for intranasal foralumab and underscores our commitment to advancing innovative treatments and immune based approaches for autoimmune diseases."

The double blinded, multicenter placebo-controlled Phase 2 trial is expected to be completed by the end of 2025, with all participants, including those initially randomized to receive placebo during the blinded phase, having the opportunity to continue to participate in a further 6-month open-label extension (OLE) study. The OLE phase aims to further evaluate the long-term safety, tolerability, and durable effectiveness of foralumab in a larger number of patients.

SEE: Open: 2.14p Trade high: 2.35p

Gosh Watching, you only bought some more SEE yesterday, despite your losses, and sold for max of +8% today, and that's before fees and the spread. You're quite a trader working on those fine margins! Wyn has obvs made an impression on you!

You ARE telling the truth aren't you, Watching2?

'an average of 44p'

without trading is indeed impressive. Well done.

I'm at around 140p so need a four-bagger to get to where I was.

Regarding the wider point; No one here believes an offer has been made so far, it's just the tribalism of the BB talking.

Well done Watching2 on buying SEE yesterday. Must have reduced your losses with today's bounce back.

That's good Saint, but are you in profit on your recent top-ups?

My last top-up was at 55p.

I think that if the management of AVCT had received an offer, had kept it secret, not dropped a leak (a la Wood Grp PLC) and allowed the sp to fall to 37p instead, they must be utter morons.

AIM might be imperfect but it's a competition for shareholder support. If people see better returns at Wood grp, SEE (our esteemed friend Watching made a substantial investment there only yesterday, and not in AVCT) then the SP will fall and then the CLN leads to more dilution / death spiral.

I've never felt less optimistic and actually sold a bit yesterday at a big loss and put elsewhere (Wood, not SEE). If I'm doing that then you can be sure other (and 'reliable') people on this bb are doing the same.

I didn’t stay up to watch to the see the outcome but I’ll tell you what, I’d much rather take AVA6k than have the operation she went through.

I think the woman featured has SGC in her cheek. They mentioned ‘rare cancer in salivary gland’ / parotid tumour. Worth a watch.

It was a test Watching. You wrote green boxes were appearing:

'Green boxes everywhere lol

Ignore the muppet show '

Plural. That implied I was a green box and you didn't know what I'd written, referencing your August AVCT prediction.

Just another fib of yours. Honestly, you are the least able poster on here.

I did read the RNS but little interest as no spare funds. And SEE is still 50% down so glad I didn't invest the last time.

Watching2, and I believe in good faith, told me (us) to keep an eye on SEE. Watching was confident and invested. I bookmarked it at 3.92p.

Today it's hit 1.97, so a loss of almost 50%. Anyone who listens to Watching2's observations might as well play roulette as that's as likely to make you any money.

SEE

Seeing Machines Ltd ORD NPV (DI)

1.97p

-0.11p -4.97% 1 3.92

'Investors will miss out if they listen to certain individuals on here'

I sometimes wonder if watching2 isn't a closet deramper, starting these conversations off.. (yet often also saying "don't reply" to people who have queries).

Watching: 'Investors will miss out if they listen to certain individuals on here'

Finally a post of yours I can agree with Watching!

Here's a good example. I wonder if anyone listened to you at 67.5p?

'Watching2

Posted in: AVCT

Posts: 8,238

Price: 67.50

No Opinion

RE: Nanoparticles and AVA600015 Aug 2024 22:10

'Geeman anyone buys at todays price will make money imo'

So nearly sold a few at the top.. Obvs wish I had pressed 'accept' now but I'd have spent elsewhere by now so perhaps for the best.

Sub $1 must be coming but for how long, and will I top up on the lows?

I'm very glad to hear of your survival DTW; it feels as if one of 'Our Own' was at the centre of history.. I'm almost proud.

I dare say that your positive energy could actually have deflected the bullet, the margins were so fine.

Whenever they show pictures from the rally in the future I feel that most avactarians will think of you.

Have a great Mar-a-Lago weekend :-)

I had wondered what had happened to regular poster Donald Trump's Wig.

Seems like a good time to express my worry here...

DTW seemed to stop posting completely around the time DT's ear was grazed by a bullet. Perhaps the wig took a direct hit?? Would they have bothered to tell us?

Quick search: (Muslims) are allowed to work on Fridays, it is mentioned in the Quran. What isn't permissible is working during the prayer. O you who have believed, when [the adhān] is called for the prayer on the day of Jumuʿah [Friday], then proceed to the remembrance of Allāh and leave trade. That is better for you, if you only knew.