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Last month Scancell published data from the translational, open-label study Phase II SCOPE study of SCIB1/iSCIB1+ in advanced unresectable stage III/IV melanoma.

Immunobody® DNA active immunotherapies iSCIB1/iSCIB1+ plus standard of care successfully achieved the SCOPE study objectives, showing excellent results encompassing efficacy, durability, immune responses and safety. The key aims were to select the optimal candidate for future development and to define the target patient population.

SCIB1 efficacy is restricted to 30% to 40% of patients with the appropriate HLA haplotype, whereas iSCIB1+ addresses a much wider HLA patient population. The latest SCOPE data have clarified that iSCIB1+ works as expected in the predicted HLA types, which represent 80% of melanoma patients - effectively double that of SCIB1.

SCOPE data for iSCIB1+ in the target HLA patients appear to show around a 20% improvement in several parameters, including overall response rate and progression free survival, when benchmarked against historical standard of care data. This has accelerated development plans for a potentially pivotal Phase IIb/III trial, with Scancell planning to meet with the FDA later this year.

🖥️ View the presentation: https://lnkd.in/dAadxmwQ

Leaky leaky?

Yes the air is leaking from your lilo SW.... getting a bit flat.

I don't think the conversion will come early - lenders will take advantage of up to 12 months @ 12% interest - and benefit from the findings from all the Rukwa appraisal activity and Galactica production. "Lenders" do not typically make good "risk" investors and if they exercise with their 20% discount there is NO guarantee that they would be able to cash in on that discount; and they certainly would NOT risk taking a loss on the equity when there is a guaranteed 12% coupon on the lending.

Not in my view. Pipeline commissioned in July ready for connection in August. CH1 could be drilled in May/June and be ready for connection in August/Sept.

Oh and M&P rig could be available for June and would be cheap....

Rig Tender? Maybe but I am not expecting it to arrive anytime soon and the tender is okay but wont do much for the sp if the anticipated CH1 spud date is still mid 2026; small and brief spike perhaps, in my view. Different if, as some are optimistically suggesting, Q1 2026 spud for CH1. I personally am heavily discounting that as a possibility.

To be totally honest McNol "the drills" won't be turning on that 187 million either for that matter.... PI input is just to pay the wages, keep the lights on and pay for BoD attendance at US Helium events!! 😉

I hope it works for you Watchouse. Personally, I think it is "toppy". I have top-sliced several millions at about that price since the 21st July. Though I do expect there to be a brief spike on the Pipeline news soon.

Well (so far) no-one has yet been able to demonstrate what allocation they have been awarded - they have simply seen their payments taken which, in my experience is "normal", but having that payment taken is not evidence that it has all been "spent"....

My cash has also been withdrawn but still doesn't show any shares allocated to my account(s). Moreover in a similar transaction recently the whole sum initially disappeared only then to be partially refunded once the reduced allocations were announced and then made a day or two later....

Protected Gas? Ask SCIROCCO? You mean the same SCIROCCO that was once a JV partner in Kiliwani and Ntorya? And what would they know about "protected gas" that AERX or ARA would not already know?

Better you keep your ignorant trap shut Prosiciunto rather than demonstrate your total lack of any knowledge relevant to the JV partners' situation...

Seawitch - you say you have been accepted on II? How do you know? I cannot see anything on my portal....

If they were sold all the way down into the 0.40's there would be no feckin' profit!! 🫏🙄

EUA, the "lenders" will get a 20% discount to the VWAP over the preceding 10 days - 20% is 20% - it makes no difference to their "profit" - the bigger question is will they be able to sell them in the market without destroying that 20% margin? They will be better able to do that with a higher share price as they will require fewer shares and the sale of those shares will represent far smaller proportion of the issued share capital and market captitalization.

; also likely to be selling into a stronger market.

McNol, you are on II aren't you? Where did you see that? I cannot get the same confirmation as far as I can see.

Yes McNol I am now regretting not piling in for quite a few more.... at least three times more.

I am just really intrigued to see how many of the £22k (circa 4m) I will have been allocated. 😊

"Rich News Flow coming soon...."

How can you tell? Is it "leaky"?

It must be the vast number of 30k trades taking place today? They are always a give away!! IN SW's head anyway.... 🤣

"only 3% of the entire issued share capital" is what I should have said! Doh!

The PI issue is only 3% of the entire share issue - even if they were all sold into the market (highly unlikely anyway) it is unlikely to create a fall back to 0.54p in my view.

Moreover there is nothing to stop shareholders selling today, to then get reimbursed with the shares they get given on Monday....... they may find they sell more than they receive BUT if as you state the shares will go back to 0.54p they won't have a problem will they? They will have a "covered" short.

You would have to have been a shareholder on the 18th July I believe.