Member Info for Bramley1967

Looking at the Condor website it seems the Condo study are not only looking at how accurate the tests are but also how they work in real life situations. This is what it says
"We will assess the performance of tests outside of the controlled laboratory environment, in the real world, in a number of settings"
No doubt they will have a scoring matrix that will be weighted in certain areas based I feel this statement
The United Kingdom and wider world is in the midst of the 2019 novel coronavirus (SARS-CoV-2) pandemic. Accurate diagnosis of infection, identification of immunity and monitoring the clinical progression of infection are of paramount importance to our response. Widespread population testing has proven difficult in western countries and has been limited by test availability, human resources and long turnaround times (up to 72 hours). This has limited our ability to control the spread of infection and to develop effective clinical pathways to enable early social isolation of infected patients and early treatment for those most at risk. The life sciences industry has responded to the pandemic by developing multiple new in vitro diagnostic tests (IVDs). To leverage the potential clinical benefit of those tests we require efficient but robust clinical evaluation. Therefore, to optimise resource utilisation in this global pandemic, we will conduct a platform adaptive diagnostic study on a national level, utilising a national network of expertise in the evaluation of diagnostic technology. CONDOR is the overarching platform which will be providing coordination, and as such, it has been deemed not to require submission to the HRA. Two research studies (FALCON and RAPTOR) which feed into this platform. This study will enable the evaluation of multiple assays in three priority areas: (1) Evaluation of the diagnostic accuracy of IVDs for active infection with SARS-CoV-2 (2) Evaluation of assays monitoring the immune response to SARS-CoV-2 infection (3) Evaluation of the prognostic value of commercially available tests for predicting prognosis in patients with suspected or confirmed SARS-CoV-2 infection. (This arm will not be active immediately but may be activated after initiation). Recognising the need for a holistic, specialty-agnostic approach, our overall programme of work will take place in both primary and secondary healthcare settings, spanning the breadth of a patient's journey. The study described in this application (referred to as FALCON) focuses only on secondary care settings. A separate study (RAPTOR) is being initiated to evaluate IVDs for COVID-19 diagnosis in community setting
Hopefully they will have to publish the results
regards
Bramley 1967

https://www.nihr.ac.uk/news/new-13-million-national-research-programme-to-evaluate-coronavirus-tests-in-hospitals-general-practices-and-care-homes/25111

Its really important we perform well in these tests as its how we will be accepted onto the NHS going forward. I have no doubt we will as we keep on evolving. This looks like a lengthy progress but will keep checking it they publish a list of who they are looking at.
regards
Bramley1967

Hi All
I have been investigating what method the NHS will use to evaluate the tests that will be used for the new 5 billion pound project and have found this the new Condor program
First mention is in here and shows who is on the board and what they are looking at
The program will be led by the Manchester University NHS Foundation Trust, the University of Manchester and the University of Oxford in collaboration with four NIHR Medtech and IVD Co-operatives as well as the University of Nottingham and the National Measurement Laboratory. It will also collaborate with the National Institute for Health and Care Excellence to assess individual tests’ benefits.

“For example, we’re going to look at tests that use different approaches to collecting samples other than the nose and throat swabs, which are uncomfortable,” said Richard Body, professor of emergency medicine at the University of Manchester. “Some tests in development at the moment measure the virus in saliva, which is much easier and more convenient to collect.”

secondly I found this

http://www.newcastle.mic.nihr.ac.uk/condor-platform
The NIHR Newcastle In Vitro Diagnostics Co-operative are part of a national partnership awarded £1.3M to robustly evaluate new COVID-19 tests

Published: 24/06/20
A key part of our response to the COVID-19 pandemic is the development of accurate tests to: identify individuals infected with SARS-Cov-2 (the virus causing COVID-19); monitor the progression of the disease and find out whether individuals have developed immunity. The life science sector has responded swiftly to this demand, developing over 240 CE marked tests related to COVID-19. Some of these tests have the potential to increase the speed and convenience of testing. However, due to the urgency of the situation, many of these tests have received emergency use authorisation based on limited preliminary data. There is a need to rigorously evaluate the performance of these tests, particularly in a real-life context, so we can introduce the most effective and reliable new tests as soon as possible.

The NIHR Newcastle In Vitro Diagnostics Co-operative (Newcastle MIC), a partnership between Newcastle Upon Tyne Hospitals NHS Foundation Trust and Newcastle University, have received funding from the National Institute for Health Research (NIHR), UK Research and Innovation, Asthma UK and British Lung Foundation to form the agile COVID-19 National DiagnOstic Research and Evaluation Platform (CONDOR) with partners across England who are fellow experts in evaluating new diagnostic tests. The platform has been recognised as nationally prioritised by the Urgent Public Health Panel and will allow us to have a co-ordinated approach to rapidly and robustly assessing new tests for COVID-19 including ones which have been prioritised by the government and its scientific advisors within the New Tests Approvals Group and Viral Detection Tests Approvals Group
This needs more investigation team?

Hi everyone
Think we are all going a bit of track with the take over chat today. Whilst if would be lovely whether it be £5 to £23 which I’ve seen talked about today we have no evidence for this and it’s all pure speculation. There are some dots lining up ie directors buys, clearance of debts, Mortgages paid off. All of these could be getting your house in order or it could be wouldn’t we all do those things if we had cash rolling in.
I feel we would be better putting our energy into great research like we had yesterday into the issues we do know are true
How involved will we be with the NHS 5 billion plan?
How involved will we be in the WHO act program
Airport testing
How new mobile test. We are almost in July. What can it be used for and what’s the implications of this
USA and other sale figures.
There is a lot to be excited about already. Don’t get me wrong we all dream of the takeover but for now we should focus on the fundamentals surely
Regards
Bramley1967

Hi Chrishar
From our latest RNS you will see we acknowledge the shortage of reagents which is one of specific selling point of our New test
I agree just look at the Roche announcement about not being able to supply
See below
ExsigTM Direct and ExsigTM Mag
In addition to supporting laboratories through the supply of its COVID-19 test, Novacyt has developed two RNA extraction kits, ExsigTM Direct and ExsigTM Mag, to help address the current reported global shortfall in extraction reagents required to perform PCR testing. The extraction of RNA is a key pre-analytical step in COVID-19 testing and must be performed before running the PCR test on the RNA extract. The two kits can be used with all open instrument platforms for running a PCR test and offer customers different benefits; ExsigTM Direct provides significant workflow improvements whilst ExsigTM Mag offers enhanced sensitivity of the Company’s COVID- 19 test.

Hope this answers your question
Regards
Bramley1967

Hi Prop5. I think you have just misinterpreted the information. What the thread is saying is we have two tests that can extract the rna.
You make have missed the news in the week that the French are issuing vouchers as a trail for the population to use in private clinics that might be using out tests. If you look back on the bb you will come across it.
Hope that helps
Regards
Bramley 1967

Hi earth70000
It does feel like the tide is about to term. Let’s hope you are right as we need some volume into the share to truly see it rise. There has been some great research and of course bought about by some very interesting opportunities that have arisen which looks like we are in a perfect place hopefully to take advantage of.
These are all happening which hopefully we will play a part in imho
NHS five pillars investing 5 billion into a long term strategy to tackle the virus.
WHO act set up to globally tackle the virus with another long term strategy 500 million tests required
Airlines testing before flights.
Unknown’s still
What’s our USA sales figures and strategy there
Mobile testing being launched very soon in July what’s the full picture here and what opportunities wil this bring with it
So many exciting items on the agenda it’s going to be a very interesting time going forward.
Regards
Bramley1967

Good evening Van and Saintsmith. Thank you for your words. If I’m honest I though that we had lost our way of late with the bb. As the sp has fallen and fallen it seemed we lost our way. Some evenings all we had were people just abusing others which went on and on. If I was a new investor I it would have quite frankly put me off.
Today I feel we have put ourselves on track. Gone are the derampers and people just asking when are we getting another RnS.

Obviously it helps that currently we have had lots to discuss with some of the most amazing developments that I sincerely hope for myself and a lot of people that invested in this share we will be involved in. We really could have the most brilliant update in the share. We certainly need my investment and volume traded and I feel that with all this renewed interest this will now naturally come.
What we now need is the company to put some meat on the Bone with current sales and profit figures. We all feel the mcap is too low but we need proof of this.
I genuinely feel very optimistic tonight and o haven’t felt like that for a long time.
Let’s see what the weeks ahead will bring.
Regards
Bramley 1967
Ps 1 billion mcap. 1
£15 a share imho. It’s coming. As I said Earlier today’s
It’s not what you know. It’s WHO you know !
Imho

Part 2
Emirates
Emirates have decided to test before flights
https://mobile.twitter.com/footyfacts90/status/1276869139680899073/photo/1
We think they will be using our tests
https://dunyanews.tv/en/Pakistan/549159-Shehbaz-Sharif-tests-positive-coronavirus

https://www.gulftoday.ae/sport/2020/06/25/pakistan-cricket-board-disappointed-with-all-rounder-hafeez-for--making-covid-19-result-public
https://www.pakshows.pk/tag/nazir-ahmad-chohan
Conclusion
• If this is our test being used this could mean a large order
• Possible use of our new mobile test kit when launched seems a logical progression
• Other airline might fully Emirates lead.

So all in all a good day, we have managed also to get this noticed on the French board which I feel is really important as we need their sentiment.
This is just from today’s new we still have
• Orders from the USA I posted a lot about this is the week which we all discussed
• Our own NHS £5 billion plan what part will we play in this?
• Mobile testing we know it’s coming In July
• Orders from the month, we know the virus has been taking hold in many countries that we recently have approvals for.
I felt slightly despondent on Friday after the rise we had Thursday. We have had great engagement on the board today and some cracking pieces of research to find the relevant items.
This is so refreshing to see after some of the petty childish behaviour and tittle-tattle we sometimes get. We want investors to see that this is a fantastic company to be invested in. We certainly have the credentials of one of the best covid stocks to be invested in and IMHO our current sp is so undervalued. Once people wake up to the absolutely massive potential that this company has to offer. I feel a lot of public perception is we have had a problem, lockdown has cured it and its back to normal. We have seen that this is not the case with the virus still gaining and the death tolls still rising. This is going to take years to sort out. Not just us but governments and countries around the world have lost billions because of the virus. They do not want this to happen again or reoccur in a couple of months so huge amounts of money is being offered up you only have to look at our own £5 billion plan from the NHS.
Lots of news to take in all of which will have a massive impact I’m sure over the next few weeks. WE just need to hear it all from the horse’s mouth.
All IMHO DYOR
Regards
Bramley1967

Consultation of what we know from today from all the contributions from me and
gggg21, EXMEX, Simple00,saintsmith, smokieUK, ak_gabba,Pineapple288 and others

WHO ACT policy and associated links
https://www.who.int/news-room/detail/26-06-2020-act-accelerator-update
https://twitter.com/RJ41468213/status/1276789204073275398?s=20
https://www.who.int/emergencies/diseases/novel-coronavirus-2019
https://novacyt.com/wp-content/uploads/2020/04/Novacyt-WHO-approval-ENGLISH-08.04.2020.pdf
https://www.theglobalfund.org/en/covid-19/health-product-supply/#products

The direct links to the WHO news room

https://www.who.int/news-room/detail/26-06-2020-act-accelerator-update

And direct link to the pdf detailing the diagnostics

https://www.who.int/docs/default-source/coronaviruse/act-consolidated-investment-case-at-26-june-2020-(vf).pdf?sfvrsn=2f9386e4_2

500 million tests needed. We are well placed for this as our last RNS states
COVID-HT test
COVID-HT is a new test for COVID-19 optimised for use in laboratories performing high volumes of tests. The CE Mark test has been designed and validated to perform at the same high levels of specificity and sensitivity as the Company’s existing COVID-19 test.
COVID-HT uses the Company’s proprietary master mix which, unlike the standard COVID-19 kit, requires no premixing, and the test components are packaged to facilitate a more streamlined workflow in a highly automated laboratory setting. As a result, COVID-HT is expected to improve operational efficiency and save time and labour associated with handling and preparing the test for use.
ExsigTM Direct, ExsigTM Mag and COVID-HT are immediately available and manufacturing capacity has been developed to meet potential demand.

EUL listed products:

https://www.who.int/diagnostics_laboratory/200407_eul_sars_cov2_product_list.pdf?ua=1

Roche test:

https://www.who.int/diagnostics_laboratory/eul_0504-046-00_cobas_sars_cov2_qualitative_assay_ifu.pdf?ua=1

Primerdesign test:

https://www.who.int/diagnostics_laboratory/eul_0489_185_00_path_covid19_ce_ivd_ifu_issue_2.0.pdf?ua=1
Conclusion.
• WHO have set up ACT that require 500 Million Tests any part of this number is huge
• Nova have always had a strong relationship with WHO
• Nova had two new tests that can help with this one of which HT we don’t have the full details of but could IMHO have been specially designed with this need in mind
• President Macron was at the launch of ACT

This links in nicely with what we know about Roche and their in ability to produce enough tests to keep up with demand.
What we know
https://uk.reuters.com/article/uk-health-coronavirus-treatments-roche-idUKKBN23Y0EH
https://twitter.com/iMuesliBrown/status/1276834278601523208
https://www.genesig.com/assets/files/Path_Coronavirus_COVID_19_CE_IVD_IFU_Issue_10.pdf

Conclusion
• If Roche cannot produce enough then these customers will possibly look elsewhere.
• WHO might not consider them for th

What about if it’s just a red herring from Roche so they get some headlines this week to say they can’t supply. I do find it strange why you would want to publish that fact. Then hey presto next week they have bought us out so that they look like hero’s
Everyone’s a winner
Just a thought

Can’t see anything on the French board yet. We need to get this over there. Can someone post on there as we need the French sentiment behind this as they have a major part to play. I’m surprised they haven’t yet seeing as President Macron was in the initial talks.

That’s good research saintsmith and just confirms even more what could be an explosive week ahead.

Hi Smokie
The good news is it could be us. Let’s look at the facts
1) we on the last RNS were surprised by a new test for high volume tests. So fits the box On what WHO wants to achieve. Have you watched the 1 hour long press conference which is already on the WHO website set for this Monday here Is the link

https://www.who.int/emergencies/diseases/novel-coronavirus-2019

2) We were WHO approved early on this is what GM said at the time
Graham Mullis, Chief Executive Officer of Novacyt, commented:
“The Emergency Use Listing by the WHO importantly provides further validation of our COVID- 19 test and gives government agencies around the world further confidence in the effectiveness of our test.

Here’s the link
https://novacyt.com/wp-content/uploads/2020/04/Novacyt-WHO-approval-ENGLISH-08.04.2020.pdf

There is a lot to be said about relationship and if not what you know but WHO you know !!!!!

3) We supply and already have distribution key partners globally. Here’s the link

http://www.primerdesign.co.uk/about/distributors?testcss=1

4) We continue to gain global approvals this is from the RNS in June

Regulatory – other territories
During the last few weeks, Novacyt has secured registrations and regulatory approvals in the following new markets for its COVID-19 test: Panama, Ecuador, Columbia, Peru, Paraguay and the UAE.
Here’s the link https://novacyt.com/wp-content/uploads/2020/06/Novacyt-COVID-19-update-02-06-20-ENGLISH.pdf

5) President Macon attended the ACT launch. I wonder who has a globally known WHO approved company in France.

Think we are well placed here and we should be excited.
Regards
Bramley 1967

I’ve just watched the video. Just imagine if we are the WHO partner when it comes to this. 500 million tests. It made me go back and read the last RNS which says.
COVID-HT test
COVID-HT is a new test for COVID-19 optimised for use in laboratories performing high volumes of tests. The CE Mark test has been designed and validated to perform at the same high levels of specificity and sensitivity as the Company’s existing COVID-19 test.
COVID-HT uses the Company’s proprietary master mix which, unlike the standard COVID-19 kit, requires no premixing, and the test components are packaged to facilitate a more streamlined workflow in a highly automated laboratory setting. As a result, COVID-HT is expected to improve operational efficiency and save time and labour associated with handling and preparing the test for use.
ExsigTM Direct, ExsigTM Mag and COVID-HT are immediately available and manufacturing capacity has been developed to meet potential demand.

To meet potential demand. Now we not had the official launch on this I believe? Correct me if I’m wrong?
Also the news briefing for Monday is already on the WHO website. They talk private industry and how £2billion is needed for tests now as this is the first pillar. Also President Emmanuel Macron met to Launch the ACT program.
Also one of the questions in the briefing was Astra Zeneca has the most advanced vaccines and is also going into phase 3. We partner with them it would make sense they would want to use our test?

Everyone this is huge huge news if we are involved in this as this will be the biggest orders and again gives us firm foundations going forward.
This is very very exciting, it’s bigger then a USA order it’s bigger then any order.
IMHO this is why our new test has been made. Is this what the film makers were doing the other day.
DYOR.

to launch the Access to #COVID19 Tools Accelerator - a global initiative between multiple partners to ensure equitable access to life-saving tools for COVID-19"-

We currently have 2.16% of the capital traded today. I agree its being kept down as we speak looking at the french order book there are 153 buys against 48K worth of sells. If they let that through it would gain. I suspect we will get to 3.30 and if the demand is still there we will see a rise. Also people will be buying in in case of a Monday news story?

Some good Volume going thorough we ended up yesterday at around 3.5% of the capital traded and today we are up to 1.69% so tracking well to exceed that. I suspect a lot of day traders and nervous high holders sold this morning as we hadn't had that high since the 18th of June at 258p, so predictable dip IMHO. We should hopefully see a predictable daily pattern slow build now, will stay stable and then a climb so that holders are in in case we do have an RNS at 7am Monday.
But to go back to my original point we will only see the sp climb with volume and so far it looks encouraging
regards
Bramley1967

We need to consolidate the rise yesterday so don’t let those mm get their hands on your golden tickets. The news will be released and it could be so many things. Massive sales, USA partner , USA sakes figures. Sold to any many of countries that are having the worst of times. Governments stockpiling for second wave. Nhs part of the 5 billion fund coming our way for sales in the next 4 years. Indian sales, new mobile testing coming. The list goes on and on. Lockdown ending in so many countries seeing peaks because of people know spreading the virus again.
Don’t sell out now as the best of times are coming
IMHO
Regards
Bramley1967

hi dannywild you say our tests now meet the two gene test for France . I must admit I've missed that. I had a look through the tech spec and couldn't see it and it hasn't been talked about on the French Board Can you provide a link where it confirms that and we will get it posted on the French site ?

When I originally posted this I didn’t think it was that complicated. So its correct our test isn’t used by the French government because it doesn’t meet their 2 Gene policy so it is not reimbursed by the government.
However the government as it says on the press release is giving out vouchers for the population to use at private healthcare centres. So nothing to do with reimbursement these vouchers can be used at private Healthcare centres where our test is approved to be used. Hopefully some of these centres might be wise enough to be using the gold test of tests ours. It’s not the amount of tests but more the sentiment that the Government has found a way around of other tests being used that doesn’t meet their 2 gene policy. This might give us a foot in the door.
Regards
Bramley