RE: What data will be given for science day?12 Feb 2023 10:03
An important nuance to presented data is that early efficacy is normally presented as reduction in tumour size. While a positive sign, it’s not always a finite indicator. Tumours do become dox immune over time, so can and do get a second wind.
It’s very rare for a study to report on how much dox is landed in the TME vs baseline. If they pull a 20x number out of the bag on SD, this is huge.
Paradigm shift.