COG-UK Handover13 Sep 2021 12:48
Source:
https://www.cogconsortium.uk/how-sars-cov-2-sequencing-is-becoming-a-national-service/
Apologies if posted b4
COG-UK has now initiated the handover of routine sequencing to a national sequencing service run by the four UK public health authorities to provide a sustainable, long-term framework. Here, we depict our transition journey and celebrate the lasting legacy of COG-UK sequencing efforts.
1 Apr 2021 Transition initiated
After 13 months of being the UK’s SARS-CoV-2 genome sequencing body, COG-UK began developing a plan for transition of routine sequencing to Public Health England (PHE) on 1 April 2021. COG-UK sites in Northern Ireland, Scotland and Wales (Glasgow, Edinburgh, Cardiff and Belfast) are supporting the transition of Pillar 1 (NHS samples) and Pillar 2 (samples from testing in the community) to their respective public health authorities. In addition to sequencing and knowledge transfer, COG-UK handed over the responsibility for shaping the sampling strategy (how sequencing capacity is used and prioritised) to NHS Test & Trace. While we no longer determine what is sequenced, COG central operations continue to provide feedback on the prioritisation model.
26 May 2021 COG-UK as a safety net
With all English Pillar 1 samples migrating for sequencing to PHE Laboratories, COG-UK academic partners stepped in to support the Wellcome Sanger Institute by distributing and sequencing high volumes of Pillar 2 samples (a minimum of 5,000 a week). During this time, the COG-UK network has repeatedly exhibited its proficiency and flexibility as the sites stood ready to take the strain to maintain continuity throughout the transition. Importantly, COG-UK ensured a seamless transition of sequencing and project management of several core national studies (including The Office of National Statistics {ONS} COVID-19 Infection Survey and the ‘Investigating a vaccine’ study).
2 Aug 2021 Successful completion
From 2 August 2021, two COG-UK sites in England remain on standby for surge sequencing.
With our role in national sequencing successfully handed over to public health agencies, COG-UK will continue its focus on research, data linkage and global training.
1 Oct 2021 Research ahead
Throughout the pandemic COG-UK has provided open access data and protocols to the global science community, and remain committed to research and improving the linkage of sequencing and public health data. CLIMB continues to provide essential infrastructure as a trusted environment for sharing of genomic data for public health surveillance between the four nations and collaboration with academic researchers. Our work with Health Data Research UK (HDR UK), the four UK Public Health Agencies and other data custodians is crucial to enhancing our understanding of COVID-19. This work focuses on progressing linkages between important COVID-19-specific datasets with viral genomic data from COG-UK, including human genome sequence data and detailed