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Summit Therapeutics gains worldwide patent protection for C-diff drug

Tue, 19th Jan 2016 12:48

(ShareCast News) - Summit Therapeutics has won a key patent protecting its novel antibiotic, ridinilazole, for the treatment of infections caused by the Clostridium difficile hospital superbug.The patent will grant Summit exclusivity in Europe for the use of ridinilazole in the treatment of CDI until at least 1 December 2029, following similar protection in other major markets, including the United States and Japan.The patent grant and its emergence from a period of opposition meant it was now effective in all major markets. Chief executive Glyn Edwards said: "The robust patent portfolio for ridinilazole, together with the strong Phase 2 clinical data showing statistical superiority over vancomycin, the current standard of care, further strengthens the potential commercial value of this novel product candidate in the treatment of CDI."With between 0.45m and 0.7m cases of CDI in the US annually, there remains great demand for better treatment of the infection.Top-line results from a Phase 2 proof of concept trial reported in late 2015 showed that ridinilazole, an orally administered small molecule antibiotic, was statistically superior to vancomycin, the current standard of care, in the endpoint of sustained clinical response.SCR was measured as cure at the end of treatment and no recurrence of CDI within 30 days of the end of treatment.Shares in Summit were up 1.6% to 131p at 1305 GMT on Tuesday.
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11 Sep 2012 08:20

Summit Corp rises on technology agreement

Shares in Summit Corporation, an Oxford based drug developer, soared 20 per cent on Tuesday after it announced it has entered a technology licence agreement with Bristol-Myers Squibb Company. Under the agreement, Bristol-Myers will use Summit's Seglin technology to identify and develop drug candida

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5 Apr 2012 15:31

Have you got a receipt for those? Next CEO in share disposal

Lord Wolfson of Aspley Guise, Chief Executive of High Street retailer Next, has made his first sale since March 2007 in a move which triggered a widespread sale of the company's shares. Wolfson, who has stood at the helm of the chain store since 2001, sold off 125,000 shares at 3,057p each for a t

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4 Apr 2012 10:01

Storm of activity at Summit as fund raising announced

It's all go at Oxford based drug developer Summit Corporation as the firm announces a five million pound share placing, appoints a new Chief Executive and reveals encouraging results for an anti-superbug drug. The company says it will issue 166,666,670 new shares at 3p per share to "certain institu

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6 Mar 2012 14:37

Small caps round up: Summit Corp, Jubilant Energy, Solo Oil...

Summit Corporation, a drug research group, has reported positive data from in vivo studies in its drug discovery programme targeting Alzheimer's disease and related neurodegenerative disorders. The most recent tril has discoved a way to enable the drug to penetrate the Blood Brain Barrier and enter

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30 Mar 2011 16:31

Summit platform attracts interest

Drug discovery company Summit Corporation is in discussions with potential partners for the Seglin platform. The Seglin platform enables the identification of mew treatments. The platform is being used to identify cancer and metabolic diseases treatments. AIM-quoted Summit suffered a operating c

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14 Mar 2011 12:25

Positive trial results for Summit drug

AIM-quoted Summit Corporation has revealed positive non-clinical efficacy results for SMT C1100, a treatment for Duchenne muscular dystrophy (DMD). The Summit share price rose by nearly one-fifth following the announcement. DMD is caused by the loss of a protein called dystrophin which results in

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12 Oct 2010 15:31

Positive results for Summit's superbug treatment

Drug discoverer Summit Corporation says that trials of its SMT 19969 C. difficile treatment show that it is superior to existing treatments. Summit has the backing of the Wellcome Trust, which is funding the programme. SMT 19969 provides protection from initial and recurring infections. There is

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4 Aug 2010 16:28

XP Power founder trims holding

XP Power deputy chairman James Peters raised £1.47m from a share disposal two days after bumper interim figures from the power control products supplier. Peters sold 200,000 shares at 735p each. Peters founded XP in 1988 and still owns nearly 2.7m shares, which is equivalent to 14%. That still mak

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3 Aug 2010 16:26

Small caps round-up: Devro, Catalytic Solutions, Summit

Sausage casings manufacturer Devro reported a sharp rise in interim profit and a 40% increase in its interim dividend to 2p a share. Pre-exceptional profit was 86% ahead at £17.1m as sales increased 11% to £116.1m in the six months to June 2010. The market for collagen casings is growing at 5% a y

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8 Jul 2010 09:48

MARKET TALK: Singer Initiates Summit Corp. With 11p Target

0848 GMT [Dow Jones] Singer Capital Markets initiates coverage of Summit Corp. (SUMM.LN) with an 11p price target. The broker says the drug development and research services firm has a promising therapy for Duchenne muscular dystrophy in early-stage clinical trials with BioMarin (BMRN), as well as a

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8 Jul 2010 09:48

UK MARKET TALK ROUNDUP: BROKERS COMMENTS

Broker comments in the UK today. Compiled by Dow Jones Newswires Markets Desk, markets.eu@dowjones.com Contact us in London. +44-20-7842-9464 Markettalk.eu@dowjones.com 0848 GMT [Dow Jones] Singer Capital Markets initiates coverage of Summit Corp. (SUMM.LN) with an 11p price target. The broker

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17 Jun 2010 07:37

Summit Corporation Sees Opportunities For Partner Funded Programs

LONDON (Dow Jones)--Summit Corporation PLC (SUMM.LN), a U.K. based drug discovery company, said Thursday it has a number of opportunities to deliver commercial success from its portfolio of partner funded programs and Seglin technology platform, adding that it is currently exploring potential collab

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24 Feb 2010 09:44

Small caps round-up: Tower Resources, Global Petroleum, Norseman Gold

Shares in Global Petroleum and Tower Resources slumped after the companies reported that the Avivi-1 well in Uganda had reached its total depth without showing any oil. Avivi-1 is owned by Tower, while Global has an option to earn a 25% interest in the licence, by funding 25% of the costs. 'Electr

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30 Oct 2009 16:31

New Travis chairman buys

Robert Walker, the chairman-designate of Travis Perkins, has bought his first shares in the builders' merchant. Walker was appointed to the Travis Perkins board on 30 September 2009 and he is due to take over as chairman from Tim Stevenson in May 2010. Walker has bought a total of 25,000 shares at

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