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EXECUTIVE CHANGES: Nuformix responds to "frustration" as CEO departs

Thu, 22nd Jul 2021 14:29

(Alliance News) - The following is a round-up of London-listed company director and manager changes announced on Thursday and not separately reported by Alliance News:

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Nuformix PLC - London-based pharmaceutical firm focused on fibrosis and oncology - Non-Executive Chair Alastair Riddell writes a letter to shareholders to address the "frustration and confusion" that followed Wednesday's announcement that Anne Brindley will depart as chief executive officer, having only joined Nuformix in December. Prior to Nuformix, Brindley was CEO of Advent Pharmaceuticals Pty Ltd, a Melbourne-based research and development company focused on generic inhaled products. Riddell says Brindley received a "significant job offer she could not refuse from previous colleagues – it is no reflection on Nuformix or her view of the opportunities in the Nuformix pipeline". Brindley will continue to push forward the company's three pipeline assets for NXP002, NXP004 and NXP001 during the six-month notice period. "All these projects are proceeding according to plan towards the inflection points previously communicated and all activities will continue to be progressed," Riddell says.

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AstraZeneca PLC - Cambridge, England-based biopharmaceutical firm - Appoints Andreas Rummelt as non-executive director. Rummelt had been a board member of Alexion Pharmaceuticals Inc since 2010. Astra completed the USD39 billion acquisition of Boston, Massachusetts-based Alexion on Wednesday. In his executive career, Rummelt was head of Technical Operations & Quality at Novartis AG. At the same time, Alexion CFO Aradhana Sarin moves to Astra as CFO and joins the board as an executive director.

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Sensyne Health PLC - Oxford, England-based clinical technology using artificial intelligence - Hires David Ruau into newly created role of chief scientific officer, starting September 1. Ruau joins from Germany's Bayer AG, where has been head of Global Data Assets & Decision Science since 2017. Prior to Bayer, Ruau was head of Scientific Computing Solutions at AstraZeneca.

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Getech Group PLC - Leeds-based provider of geoscience data and software to energy industry - Hires Emma Parker-Wilson as non-executive director, effective immediately and replacing Chris Flavel, who retires from the board. Parker-Wilson is principal in charge of Sustainable Business Opportunities at miner Anglo American PLC.

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LPA Group PLC - Saffron Walden, Essex-based LED lighting, electronic and electro-mechanical system designer and manufacturer - Confirms Peter Pollock will retire as chair and director from August 8, having served LPA for 24 years as chief executive and then executive chair. Recent board appointee Robert Horvath becomes independent chair.

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Valereum Blockchain PLC - Gibraltar-based blockchain technology builder - Patrick Young joins board as executive director, effective immediately. Young will help Valereum build the Valereum Bridge, a non-fungible-token bespoke securities financial platform aimed at linking government-issued currencies with cypto currencies. Young is author of a book on fintech and is former chair of the Blockchain Malta Association.

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Supply@Me Capital PLC - London-based inventory monetisation platform - Non-Executive Chair Dominic White steps down as director, effective Thursday, "to focus on his other business interests". A search for successor is underway.

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Providence Resources PLC - Barryroe oil and gas project offshore Ireland - Hires Peter Newman as senior independent director and Ann-Marie O'Sullivan as director, starting at the end of Thursday's annual general meeting. Newman was global head of Oil & Gas at accountants Deloitte and prior to that held a similar regional role at peer Arthur Andersen. O'Sullivan is public relations professional who has held board positions with Dublin Airport Authority and Cork Chamber of Commerce. The Barryroe project is in the Atlantic Ocean south of Cork.

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By Tom Waite; thomaslwaite@alliancenews.com

Copyright 2021 Alliance News Limited. All Rights Reserved.

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Nuformix PLC - London-based pharmaceutical development firm focused on fibrosis and oncology via drug repurposing - Starts to scale-up the production processes of lead cocrystals for its cancer programme NXP004, focused on the treatment for advanced ovarian cancer. Firm aims to develop new forms of Olaparib, "currently marketed by AstraZeneca PLC, under the Lynparza brand name," Nuformix explains. First approved in 2014 for advanced ovarian cancer, it has since received "similar approvals in breast, pancreatic and prostate cancers with further trials on-going."

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Nuformix PLC - London-based pharmaceutical development firm focused on fibrosis and oncology via drug repurposing - Says the contract research organisation undertaking the final planned pre-clinical study for its NXP002 treatment had a protocol failure, which has voided the study. Says the organisation repeated the study and recorded results that were inconsistent with the first in vivo study at all time points and also with the oral control. Notes that no positive or negative conclusions could be drawn from this study.

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Nuformix PLC - London-based pharmaceutical development firm focused on fibrosis and oncology via drug repurposing - Says patent application for key asset NXP004 had progressed to the publication phase. NXP004 is a new formulation of Olaparib, which is used to treat ovarian, breast and pancreatic cancers currently marketed by FTSE 100-listed AstraZeneca PLC, under the name Lynparza. The patent application, which was made in September 2020, covers new olaparib oxalic acid cocrystals, their therapeutic uses and pharmaceutical compositions containing them. A second patent application was filed last November which remains pending.

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