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My luck is so bad I’m gonna shirt this for a laugh.
Should be 60p by close then 🤪
And what do the charts say if this closes at 50p?
What is your position now mate? Did you hold out for 41p or was you lucky enough to get todays uptick?
Told you previously Windy on FDA approvel this will surpass the ATH, that’s an extremely viable assumption
To make. Doesn’t matter how long you have owned the stock you will still make profit if that happens. Of course you can try trade this, however what’s the point if you believe FDA approval will happen, you could try be smart one day for example the people selling this morning thinking because GSA have increased the short this would tank today but the price today is 9% up or you can just wait it out and not worry. Depends if you want to gamble or believe in the science and overall investment case. The Trial is not a fantasy, it will eventually conclude one way or another. Just a waiting game.
"Again I’m not looking at a week by week share chart, that’s just gambling. I’m looking at the overall trend of where this is heading as an investment opportunity back to a more reasonable valuation, not a quick trade. Although still awaiting that FDA approval catalyst that’s the real prize imo."
well, week by week,... hmmm... 3 years ago it was 250p.
So gambling is simply defined by the amount of time you hold a stock? Thats crap, right...
Although as you say it hinges on FDA approval, which is due very soon? so doesn't it make more sense to invest (not gamble) as short a time as possible before FDA approval is granted?
You may or may not be right about AVCT long term success, who knows, what I don't understand is your blind refusal to ever acknowledge that any development in this long torturous SP slide has been anything other than seemingly expected and a confirmation that everything has gone to plan.
It always comes across as one-eyed, blind faith rather than ever any objective assessment. (Which as an investment strategy is extremely dangerous.)
News could also be from Dr Simon Bennett the Chief Business Officer bringing his 26 years' commercial experience in the biopharma industry (so hopefully more competent than todays RNS authors). Simon has worked with companies from large and mid-sized pharma such as Bristol-Myers-Squibb and Menarini Group to early stage biotechs, supporting business development and licensing activities in addition to being involved in all aspects of business and corporate development. Simon has been involved in over 80 (soon to be 81?) commercial deals across Europe, North America, Australasia, Japan, Russia/CIS and South America. 🤝GLA
Somethings cooking! Is it frying shorters?
Whilst Avacta blockbuster assets IP potential value still to be reflected in current market cap /SP does not mean will not happen , indeed very encouraging progress being made . Plus possibility of affimers being tested in patients later this year with AffyXel JV.
--
"The global stem cell market size was valued at USD 19.41 billion in 2023, driven by the rising prevalence of various non-communicable diseases, the increasing investments in stem cell therapies, and the growing utilization of human-induced pluripotent stem cells (iPSCs). The market is anticipated to grow at a CAGR of 10.3% during the forecast period of 2024-2032 to achieve a value of USD 46.91 billion by 2032."
https://www.expertmarketresearch.com/reports/stem-cell-market
--------------------
Posted earlier 2024
Seng-Ho JeonSeng-Ho Jeon
Former CEO & President of Daewoong pharmaceuticalFormer CEO & President of Daewoong pharmaceutical
https://www.linkedin.com/feed/update/urn:li:activity:7148957324089380864/
AffyXell is a pre-clinical stage biotechnology company with a proprietary platform engine to develop novel cell and gene therapy (CGT). This platform is a powerhouse not only for internal pipelines but also for external collaboration. We have multiple discussions and collaborative studies with external parties to maximize the potential strength and expandability of AffyXell’s platform technologies.
We are dedicated to developing off-the-shelf allogenic cell therapies for the treatment of transplantation rejection and immune disorders. Our technology enables the merge of two different platform technologies from our parent companies: Daewoong's Mesenchymal Stem Cell technology (DW-MSC) and Avacta's Affimer technology.
Our lead pipeline candidate, AFX001, is designed to inhibit CD40-CD40L signaling by binding to CD40L and blocking the interaction through the secretion of an anti-CD40L antagonistic Affimer. CD40-CD40L signaling plays a pivotal role in T cell activation, T cell-mediated B cell activation/differentiation, and immune responses involving antigen-presenting cells (APCs). Inhibition of T cell and B cell activation through CD40-CD40L signaling suppression offers therapeutic potential for conditions like GvHD and various autoimmune diseases, including systemic lupus erythematosus, type 1 diabetes mellitus, multiple sclerosis, and rheumatoid arthritis.
Excitingly, we have demonstrated AFX001's outstanding efficacy compared to un-transduced MSCs using a humanized Graft versus Host Disease (GvHD) mouse model. Furthermore, AFX001 exhibits comparable efficacy to a pre-clinically verified anti-CD40L antibody.
We recently concluded a smooth pre-IND meeting with the US FDA, and we are on track to initiate patient-targeted clinical trials in the second half of this year. We are ready to manufacture GMP batch for the clinical trials with the established GMP-grade Master Cell Bank (MCB) and Working Cell Bank (WCB). " etc
Looks like we could really pop soon.
Rapid rise to 100p+ please
I wonder if anything is happening with AffyXell, we have 25% now.
I think the key point is funding sorted. Takes time to work through the extra shares.
The latest fundraise has shown how poor the UK markets are now, we need a US listing asap.
Based on today's performance the 'important announcements' to be released during the preliminary next week, are likely to be quite exciting.
Does the market have wind of something?
The strength today is sustained.
what bull ****e
so you think the stock shouldn't be above 20p based on what?
as for the bulls don't think this will get back to 60p i agree they don't they think it will go much higher in time
Don't panic TW!! Lovely to see him throwing all his foot soldiers at it today to stop the SP running. It's a game of nerve TW have you got enough to slow this down??
Not defeatist. We just need to walk again before we can run.
60p target is short term - momentum needs to build if we are to hold the move higher
Onwards and upwards
SMDC were supposed to be reviewing the data end of April will be interesting next week. Although it will just be a recommendation to up the dose and continue I'd imagine.
That short has to close at some point can see it getting squeezed here and will be funny when it does.
No MTD found
Therapeutically significant levels of dox in tumours
Patients at end of life seeing a response even though this is only a safety trial
Cleaved dox no different thhan straigt dox
Working with more potent cytotoxins now
Platform pipeline being developed
2weekly dosing results in patients with high FAP
I mean it doesnt take a genius to work out where this is heading on a fundamental basis. and the shareprice will catch up with it.
The fact is 99.999% of people on Earth haven't even heard of Avacta including various funds. What happens when the results are broadcast as what they will be. A revolution in cancer treatment.
GSA are going to look pretty silly soon enough
Maybe we can get back to 60p plus
That’s a defeatist mentality, desperately hoping it will go back to 60p. For a stock that previously traded above 100p and was touted to be a paradigm shift. Just wow.
This is a company that should be trading below 20p. Even the bulls don’t believe it’ll get back to 60p.
But but but, it's going up today - 7% so far. Does this mean there has been a leak and the market has woken up to the reality of what avacta has. After all we keep getting told the market is the ultimate arbiter.
Again I’m not looking at a week by week share chart, that’s just gambling. I’m looking at the overall trend of where this is heading as an investment opportunity back to a more reasonable valuation, not a quick trade. Although still awaiting that FDA approval catalyst that’s the real prize imo.
Ice
I’m not after a row but you could have said the same thing anytime over the last few weeks and what has happened? It’s gone down. If you mean that by mid year it will be up again then I agree😄
Slightest move up against their short and the boots are on the ground.
Have to say though I am not impressed with the basic inability to put out an RNS. Just gives the shorts fodder.
Anyway now that we have churned through the placing and convertible shares, maybe we can get back to 60p plus
What you on about Touk it’s obvious the price has dropped based on sentiment of shock placing. 19-20% dilution doesnt warrant a 70% plus drop in share price, ask yourself what has realistically materially changed from Nov price of 160 odd? If anything we are fully funded and the 2w trial is on schedule as per the Q&A. It’s all market games and negative sentiment doesn’t last forever. PS it’s not ramping based on my above reasoning. I welcome any counter points though if you have them 🤣🤔👍.
Would love it if gardiner had fvcked the REPLACEMENT up too!!
Ice ffs stop the unfounded ramping. There is no new information to support a rise at this point other than how low the SP is at the moment
But all is well because CC is a breath of fresh air so sit back and relax😂😂😂