PureTech Regulatory News (PRTC)

FORM 8.3

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY

A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR

MORE

Rule 8.3 of the Takeover Code (the "Code")

1.

KEY INFORMATION

(a)

Full name of discloser:

Barclays PLC.

(b)

Owner or controller of interest and short

positions disclosed, if different from 1(a):

(c)

Name of offeror/offeree in relation to whose

PURETECH HEALTH PLC

relevant securities this form relates:

(d)

If an exempt fund manager connected with an

offeror/offeree, state this and specify identity of

offeror/offeree:

(e)

Date position held/dealing undertaken:

08 Apr 2025

(f)

In addition to the company in 1(c) above, is the discloser making

NO

disclosures in respect of any other party to the offer?

2.

POSITIONS OF THE PERSON MAKING THE DISCLOSURE

(a)

Interests and short positions in the relevant securities of the offeror or offeree

to which the disclosure relates following the dealing(if any)

Class of relevant security:

1p ordinary

Interests

Short Positions

Number

(%)

Number

(%)

(1)

Relevant securities owned

and/or controlled:

2,205,907

0.92%

2,517,260

1.05%

(2)

Cash-settled derivatives:

and/or controlled:

2,451,809

1.02%

2,087,421

0.87%

(3)

Stock-settled derivatives (including options)

and agreements to purchase/sell:

0

0.00%

0

0.00%

TOTAL:

4,657,716

1.94%

4,604,681

1.92%

(b)

Rights to subscribe for new securities (including directors and other executive

options)

Class of relevant security in relation to

which subscription right exists

Details, including nature of the rights

concerned and relevant percentages:

3.

DEALINGS (IF ANY) BY THE EXEMPT PRINCIPAL TRADER

(a)

Purchases and sales

Class of relevant

Purchase/sale

Number of

Price per unit

security

securities

1p ordinary

Purchase

152,552

1.2300 GBP

1p ordinary

Purchase

93,847

1.1760 GBP

1p ordinary

Purchase

49,000

1.2071 GBP

1p ordinary

Purchase

41,800

1.2134 GBP

1p ordinary

Purchase

28,651

1.1823 GBP

1p ordinary

Purchase

28,186

1.2161 GBP

1p ordinary

Purchase

19,419

1.2157 GBP

1p ordinary

Purchase

18,866

1.2418 GBP

1p ordinary

Purchase

17,289

1.2142 GBP

1p ordinary

Purchase

11,128

1.2118 GBP

1p ordinary

Purchase

8,660

1.2486 GBP

1p ordinary

Purchase

8,362

1.2150 GBP

1p ordinary

Purchase

7,858

1.1826 GBP

1p ordinary

Purchase

5,000

1.2500 GBP

1p ordinary

Purchase

1,606

1.2359 GBP

1p ordinary

Purchase

519

1.2100 GBP

1p ordinary

Purchase

481

1.2520 GBP

1p ordinary

Purchase

378

1.2010 GBP

1p ordinary

Purchase

286

1.1860 GBP

1p ordinary

Purchase

242

1.2070 GBP

1p ordinary

Sale

319,914

1.2115 GBP

1p ordinary

Sale

179,673

1.2219 GBP

1p ordinary

Sale

134,381

1.2193 GBP

1p ordinary

Sale

77,849

1.2235 GBP

1p ordinary

Sale

76,662

1.2319 GBP

1p ordinary

Sale

40,542

1.2230 GBP

1p ordinary

Sale

38,965

1.2232 GBP

1p ordinary

Sale

25,463

1.1921 GBP

1p ordinary

Sale

22,552

1.2203 GBP

1p ordinary

Sale

17,757

1.2165 GBP

1p ordinary

Sale

12,310

1.2143 GBP

1p ordinary

Sale

4,114

1.2103 GBP

1p ordinary

Sale

3,991

1.2201 GBP

1p ordinary

Sale

2,549

1.2209 GBP

1p ordinary

Sale

1,780

1.2275 GBP

1p ordinary

Sale

1,457

1.2285 GBP

1p ordinary

Sale

1,160

1.2202 GBP

1p ordinary

Sale

991

1.2530 GBP

1p ordinary

Sale

865

1.2145 GBP

1p ordinary

Sale

759

1.2140 GBP

1p ordinary

Sale

382

1.1760 GBP

1p ordinary

Sale

378

1.2010 GBP

1p ordinary

Sale

270

1.2150 GBP

1p ordinary

Sale

242

1.2070 GBP

1p ordinary

Sale

179

1.2440 GBP

(b)

Cash-settled derivative transactions

Class of

Product

Nature of dealing

Number of

Price per

relevant

description

reference

unit

security

securities

1p ordinary

SWAP

Increasing Long

42,790

1.1760 GBP

1p ordinary

SWAP

Increasing Long

59,391

1.1841 GBP

1p ordinary

SWAP

Increasing Long

25,463

1.1921 GBP

1p ordinary

SWAP

Increasing Long

2,241

1.1959 GBP

1p ordinary

SWAP

Increasing Long

9,453

1.2041 GBP

1p ordinary

SWAP

Increasing Long

134,381

1.2193 GBP

1p ordinary

SWAP

Increasing Long

10,046

1.2216 GBP

1p ordinary

SWAP

Increasing Long

179,673

1.2219 GBP

1p ordinary

SWAP

Increasing Long

1,873

1.2240 GBP

1p ordinary

SWAP

Increasing Long

4,305

1.2255 GBP

1p ordinary

SWAP

Increasing Long

181,777

1.2269 GBP

1p ordinary

SWAP

Increasing Long

3,485

1.2274 GBP

1p ordinary

SWAP

Increasing Long

27,074

1.2376 GBP

1p ordinary

SWAP

Increasing Long

7,498

1.3000 GBP

1p ordinary

SWAP

Decreasing Long

33,283

1.1760 GBP

1p ordinary

SWAP

Decreasing Long

180,074

1.2277 GBP

1p ordinary

CFD

Increasing Long

5,470

1.2015 GBP

1p ordinary

CFD

Increasing Long

5,648

1.2253 GBP

1p ordinary

CFD

Increasing Long

16,624

1.2296 GBP

1p ordinary

CFD

Decreasing Long

19,363

1.1760 GBP

1p ordinary

CFD

Decreasing Long

1,468

1.3001 GBP

(c)

Stock-settled derivative transactions (including options)

(i)

Writing, selling, purchasing or varying

Class

Product

Writing,

Number

Exercise

Type

Expiry

Option

of

description

purchasing,

of

price

date

money

relevant

selling,

securities

per unit

paid/

security

varying etc

to which

received

option

per unit

relates

(ii)

Exercising

Class of relevant

Product description

Exercising/ exercised against

Number of

Exercise price per

security

securities

unit

(d)

Other dealings (including subscribing for new securities)

Class of relevant

Nature of Dealings

Details

Price per unit (if

security

applicable)

4.

OTHER INFORMATION

(a)

Indemnity and other dealings arrangements

Details of any indemnity or option arrangement, or any agreement or understanding,

formal or informal, relating to relevant securities which may be an inducement to deal

or refrain from dealing entered into by the exempt principal trader making the disclosure and any party

to the offer or any person acting in concert with a party to the offer:

NONE

(b)

Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between

the person making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights of future acquisition or disposal of any relevant securities to which

any derivative is referenced:

NONE

(c)

Attachments

Is a Supplemental Form 8 (Open Positions) attached?

NO

Date of disclosure:

09 Apr 2025

Contact name:

Large Holdings Regulatory Operations

Telephone number:

020 3134 7213