Incanthera Regulatory News (INC.PL)

28 March 2025

Incanthera plc

("Incanthera" or the "Company")

Commercial Update

Incanthera plc (AQSE: INC), the Company focused on innovative technologies in dermatology and oncology, provides the following commercial update

The Company is pleased to confirm that its immediate focus is on delivering its luxury skincare brand Skin + Cell to the market. As previously advised, the Company is in discussions with a number of parties about potential market entry points in different jurisdictions.

The Company currently has finished product in stock ready for immediate distribution.

Given the market interest shown in Skin + Cell and the short lead time for product distribution, the Company is focussing its attention on monetising Skin + CELL its luxury skincare range of products ahead of development of its pharmaceutical Sol programme which targets the treatment of skin solar keratosis and prevention of skin melanoma.

Accordingly, the Company has by mutual consent, terminated the Product Development & Licensing Agreement entered into on 18 March 2018 with Limeway Pharma Design Limited. Both parties have agreed to cross licence relevant patent rights on a royalty free basis to the extent necessary to independently undertake future work relating to pharmaceutical development for the treatment of skin solar keratosis and prevention of skin melanoma. The Company can continue to develop SOL at a future date.

Further updates will be made in due course.

This announcement contains inside information as stipulated under the UK version of the Market Abuse Regulation no 596/2014 which is part of English law by virtue of the European (withdrawal) Act 2018, as amended. On publication of this announcement via a regulatory information service, this information is considered to be in the public domain.

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Notes to Editors

About Incanthera plc

Incanthera is a specialist company focused on innovative technologies in dermatology and oncology. It seeks to identify and develop innovative solutions to current clinical, commercially relevant unmet needs, utilising new technology from leading specialists and academic institutions as well as its in-house development team.

The Company originated from the Institute of Cancer Therapeutics ("ICT") at the University of Bradford. Incanthera's strategy is to develop each candidate in its portfolio from initial acquisition or discovery to securing its future through commercially valuable partnerships at the earliest opportunity in its development pathway.

For more information on the Company please visit: www.incanthera.com

@incantheraplc

About Skin + CELL

Skin + CELL is Incanthera's luxury skincare brand utilising our ground-breaking formulation and delivery expertise, to bring scientifically proven formulations to cosmetics. Skin + CELL's complementary range of products are based on advanced, clinically designed, formulation concentrates which combine leading edge delivery enhancement technology with selected prestige cosmetic ingredients to give an effective product which gives a silky emollience in use and leaves the skin visibly radiant, energised and protected.

Incanthera's new bioactive skincare technology has been developed by our in-house experts who have previously formulated topical products for some of the world's leading skincare and pharmaceutical companies. The formulations fortify otherwise depleted physiological pathways to improve the skin's performance, ability to self-repair and to address previously unmet cosmetic conditions in skin health.

Skin + CELL's luxury skincare current range extends across face, body, hand, face serum and eye cream, and will also include bioactive SPF concentrations and further derivatives of vitamins in the future.

Forward looking statement disclaimer

Certain statements made in this announcement are forward-looking statements. These forward-looking statements are not historical facts but rather are based on the Company's current expectations, estimates, and projections about its industry; its beliefs; and assumptions. Words such as 'anticipates,' 'expects,' 'intends,' 'plans,' 'believes,' 'seeks,' 'estimates,' and similar expressions are intended to identify forward-looking statements. These statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties, and other factors, some of which are beyond the Company's control, are difficult to predict, and could cause actual results to differ materially from those expressed or forecasted in the forward-looking statements. The Company cautions shareholders and prospective shareholders not to place undue reliance on these forward-looking statements, which reflect the view of the Company only as of the date of this announcement. The forward-looking statements made in this announcement relate only to events as of the date on which the statements are made. The Company will not undertake any obligation to release publicly any revisions or updates to these forward-looking statements to reflect events, circumstances, or unanticipated events occurring after the date of this announcement except as required by law or by any appropriate regulatory authority.