CLS Holdings Regulatory News (CLI)

CLS Holdings plc

(the "Company" or "CLS")

Annual Information Update ("AIU")

In accordance with Prospectus Rule 5.2, the following information has been published or made available to the public in the 12 months preceding this announcement in compliance with laws and rules dealing with the regulation of securities, issues of securities and securities markets.

In accordance with Prospectus Rule 5.2.7 it is acknowledged that, although the information contained in each of the documents listed below was accurate and up to date when originally published, such information may at any time become out of date due to changing circumstances.

This AIU can be found in the Media Centre - Regulatory News section of our website at www.clsholdings.com.

The following UK regulatory announcements have been made via a Regulatory Information Service. A full copy of these announcements can be viewed on the Company's price page of the London Stock Exchange website at www.londonstockexchange.com. The code for CLS, which may be required for search purposes, is CLI. Copies of these announcements may also be found via CLS's website in the Media Centre - Regulatory News section.

Date of Brief Description of Announcement

Announcement

18 Mar 2011 Notice of AGM - Tender Offer 1 in every 47 Ordinary Shares

18 Mar 2011 Publication and posting of 2010 Annual Report & Accounts

15 Mar 2011 Director/PDMR Shareholdings

07 Mar 2011 Audited Financial Results for year end 31 December 2010

24 Feb 2011 Notice of Results

03 Feb 2011 Major Vauxhall Redevelopment

30 Dec 2010 Director/PDMR Shareholdings

29 Dec 2010 Director/PDMR Shareholdings

15 Dec 2010 Director/PDMR Shareholdings

10 Nov 2010 Interim Management Statement

10 Nov 2010 Board Changes - CEO

02 Nov 2010 Completion of Purchase of Apex Tower

01 Nov 2010 Director/PDMR Shareholdings

28 Oct 2010 Expansion and 10 Year Lease with Dr Hönle AG Munich

25 Oct 2010 Notification of Major Interests in Shares - Asset Value Investors

14 Oct 2010 Further Development at Landshut, Germany

08 Oct 2010 Director/PDMR Shareholdings

06 Oct 2010 Purchase of Colt Telecom's Data Centre and French HQ in Paris

30 Sep 2010 Director/PDMR Shareholdings

29 Sep 2010 Director/PDMR Shareholdings

23 Sep 2010 Director/PDMR Shareholdings

21 Sep 2010 Director/PDMR Shareholdings

20 Sep 2010 Director/PDMR Shareholdings

17 Sep 2010 Director/PDMR Shareholdings

15 Sep 2010 Completion of Tender Offer and Total Voting Rights - Amendment

14 Sep 2010 Completion of Tender Offer and Total Voting Rights

08 Sep 2010 Results of General Meeting and Tender Offer

03 Sep 2010 TR1 - Notification of Major Interest - F&C Asset Management Plc

19 Aug 2010 Notice of General Meeting - Tender Offer 1 in every 74 Ordinary Shares

19 Aug 2010 Half Yearly Report 2010

12 Aug 2010 Change of Corporate Broker

04 Aug 2010 Purchase of Apex Tower, New Malden

22 July 2010 Notice of Half Yearly Financial Report

01 July 2010 Director/PDMR Shareholdings

18 June 2010 Director/PDMR Shareholdings

16 June 2010 Director/PDMR Shareholdings

11 June 2010 Director/PDMR Shareholdings

08 June 2010 Director/PDMR Shareholdings

01 June 2010 Director/PDMR Shareholdings

27 May 2010 Director/PDMR Shareholdings

24 May 2010 Director/PDMR Shareholdings

18 May 2010 Annual Information Update

17 May 2010 Interim Management Statement

12 May 2010 Purchase of 100 Vauxhall Walk, SW8

11 May 2010 Director/PDMR Shareholdings

11 May 2010 Result of AGM and Directors Changes

10 May 2010 Director/PDMR Shareholdings

07 May 2010 Director/PDMR Shareholdings

04 May 2010 Director/PDMR Shareholdings

29 April 2010 Director/PDMR Shareholdings

28 April 2010 Change to Director's Details

28 April 2010 Director/PDMR Shareholdings

19 April 2010 Director/PDMR Shareholdings

15 April 2010 Completion of Tender Offer

08 April 2010 Result of General Meeting and Tender Offer

06 April 2010 Second Price Monitoring Extension

06 April 2010 Price Monitoring Extension

The Company has submitted filings to Companies House during the last 12 months in relation to its Annual Report and Accounts, Annual Return, changes to its Articles of Association, Register of Mortgages, resolutions passed at shareholder meetings, changes to its directors and directors' details, the purchase and cancellation of its own shares and the sale of shares from treasury. Copies of these documents can be found by contacting Companies House at Crown Way, Cardiff, CF14 3UZ or via their website at www.companieshouse.gov.uk or through Companies House Direct at www.direct.companieshouse.gov.uk.

The Annual Report for the year ending 31 December 2010, 2011 Notice of Annual General Meeting and Tender Offer Circular were sent to shareholders and filed with the UK Listing Authority's National Storage Mechanism ("UKLA NSM") on 18 March 2011. Copies of these documents can be found on the Company's website.

The September 2010 Tender Offer Circular and Notice of General Meeting was sent to shareholders and filed with the UKLA Document Viewing Facility ("UKLA DVF") on 19 August 2010. Copies of these documents can be found on the Company's website. The resolutions passed at the General Meeting in September 2010 were filed with the UKLA NSM on 8 September 2010.

The 2010 Half-Yearly Financial Report, published on 19 August 2010, can be found on the Company's website.

Documents filed with the UKLA NSM can be viewed at www.hemscott.com/nsm.do and documents filed with the UKLA DVF can be viewed at The Financial Services Authority, 25 The North Colonnade, London E14 5HS.

Further information regarding the Company and its activities is available on its website: www.clsholdings.com

A copy of this Annual Information Update and all documents referred to in it can be obtained from the Company Secretary at the Company's registered office:

CLS Holdings plc86 BondwayLondon SW8 1SF

For further information contact:

David Fuller

Company Secretary

CLS Holdings plc

Tel: 020 7582 7766