final continuation - Times article24 Feb 2014 22:24
London’s best-known bear is sharpening his claws. Evil Knievil, the notorious bear raider born as Simon Cawkwell, has his eye on a tiddler going by the name of LiDCO.
The £44 million London-based company describes its business as “cardiovascular monitoring” — providing kit to hospitals that keeps an eye on the amount of blood flowing around a patient’s body during surgery.
The market likes it. Profitable and debt-free, LiDCO was chased to its best since late 2005 this month after the Association of Anaesthetists of Great Britain and Ireland published guidelines on care for the elderly during operations that endorsed the sort of less invasive monitoring machinery that LiDCO produces.
Evil is dubious and has wagered against those shares through a spread bet with a City bookie. The source of his disquiet is a trial of LiDCO’s technology known as Optimise, carried out on about 740 patients across a dozen NHS hospitals and completed last year. Results have not been published but will, so Evil claims, prove that the tech doesn’t work.
Except that it isn’t true, the company insists. LiDCO bulls say that the scientists who carried out Optimise themselves admit that the raw data was skewed. In October, the man who led Optimise gave a 20-minute presentation of headline results at a Paris conference. True, headline data showed LiDCO’s kit had no “statistically significant” effect on patients using it, but strip out the first few patients, when clinicians were learning how to work the system, and the effect was, indeed, statistically significant. Plus, some patients were admitted to the study without meeting the criteria for inclusion and shouldn’t have been.
Researchers have gone away to analyse the data further, before results are published in full in a credible, peer-reviewed, scientific journal. Until then, LiDCO bulls argue, just look at the rate at which the NHS has been snapping up the kit. Clinicians know better than the bandits on the bulletin boards of financial websites whether it works or not.
For now, the bears seem to have the upper hand and LiDCO shares eased 2.7 per cent to 22¾p, making for a near-15 per cent decline in under three weeks.