We would love to hear your thoughts about our site and services, please take our survey here.
Woody, I think what is important to review is from Advisory board of UK Key Opinion Leaders ("Advisory Board") RNS it was mentioned ‘’ In particular the need for a treatment that can be used to alleviate symptoms even in end-stage patients was highlighted and that the co-prescription of a drug to provide supportive benefits in addition to anti-cancer benefits would be valuable from the beginning of the patient journey, alongside currently used approaches ‘’ the trial in Georgia was trialled in stage VI late lung cancer patients, with the OS and PFS extended 10.9 weeks and 7.2 weeks respectively. Now what happens if they approach it much earlier in the patient journey as mentioned by the participants individual comments in the RNS 14th June
It’s the clinical study report on 401 currently with the Ministry of Health in Tbilisi which was filed before the end of July, GM stated 3 - 6 months on the proactive interview, could this be the final piece of the jigsaw before activity?
Keytruda - Merck, was on BBC South today last night. Cant be used after 2 years of use due to no further evidence / history of its use to support it. Think NICE restricted its use but are looking to change it early next year.
Just going to share the link again found by bp82 earlier, a good read!! https://www.scitecheuropa.eu/lung-cancer-therapeutics-valiseek/88655/
Just reading the AZN RNS http://www.lse.co.uk/regulatory-news-article.asp?ArticleCode=5dtrpk13&ArticleHeadline=CHMP_recommends_Imfinzi_for_Stage_III_nsclc ‘As part of a broad development programme, Imfinzi is also being tested as a monotherapy and in combination with chemotherapy, radiation therapy, small molecules, and tremelimumab, an anti-CTLA4 monoclonal antibody, as a first or second-line treatment for patients with NSCLC, small cell lung cancer, locally-advanced or metastatic urothelial carcinoma, head and neck cancer and other solid tumours’ Do you think VAL 401 could be seen as a part of a combination with Imfinzi or tremelimumab to produce good results? Apologies about my scientific knowledge I don’t know if 401 could be combined with Imfinzi.
Quite interesting news on Val 401 competition Imfinzi haha http://www.lse.co.uk/sharecast-news-article.asp?ArticleCode=27794508&ArticleHeadline=AstraZenecas_lung_cancer_treatment_gains_positive_opinion_from_CHMP
GFB agree with your comments!! Possibly the most exciting time of Vals history, again referring to recent RNS VAL 401 update 14th June 'Advanced conversations have continued with a number of prospective partners with the aim of achieving a partnership, to progress the project appropriately towards eventual patient use'
http://www.lse.co.uk/share-regulatory-news.asp?shareprice=VAL&ArticleCode=5olarfr5&ArticleHeadline=VAL401_Update
With IMM and N4P taking a hammering for failed products, could this be Vals time to shine?!! In fact hang on, the 401 product has proved a success already with commercial chats ongoing!! ATB :)