Member Info for Tommy85

Hahaha i do enjoy RB L2 commentary, provides us with a good picture of what is going on. 'Wouldnt want to be out of this over the weekend' Called it haha :)

a kicking on Phase II top line results. Having reviewed the RNS looks quite promising in all honesty, i think people are expecting far to much in an extremely regulated industry at this current time. Also, i don't understand why other posters come on an criticize Val and its products, for gods sake we are developing something in a very meaningful space to help sufferers. I look at other companies such as 4D and SCLP and genuinely want them to succeed and wouldn't for the life of me go on the board and be little them. ATB

I mentioned Takeda last week as rumors were we that Val had previously dealt with Shire to some extent (have no idea to what end) that are now owned by Takeda

With Keytruda ORR of 24% https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574183/

Among the carnage from today, I see this post from besensible as extremely valuable. Researching the link provided - Response Rate as a Regulatory End Point in Single-Arm Studies of Advanced Solid Tumors https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574183/ It notes within, although on NSCLC (which is 401 territory), explains the Objective Response Rate (ORR) very well. For Val 201 the ORR was established at 54% today on 12 patients. Interesting to read that pembrolizumab (Keytruda - Merck) only achieved ORR of 24% and has more severe side effects than found in Val 201 to date. Again interesting reading, tomorrow is another day. GL all :)

I can remember someone stating some time ago we had some interest from Shire Pharmaceuticals (I may have this way off track so please forgive me) on 201, for some reason or another it didn’t materialise. Do you think on the cusp of 201 results there could be some renewed interest from them? Also just found Shire are now owned by Takeda (Jap Pharma) could they possibly the comp that have the MTA on 301 also? Again, thinking out loud here. Hope Suze and the crew are prepping that RNS on 201 data, I find the RNSs now so much more informative with less questions being asked after. Great platform now to build from. ATB :)

Feels like a couple of weeks ago when the rascals dropped from 25p to 18p for absolutely no reason and everyone was all at sea. Look where we are now. Just hold your nerve, we all know what we are waiting on! :)

And just to makes things easier please use this link - https://www.lse.co.uk/rns/VAL/

This is in more auctions than homes under the hammer :)

Hahahaha noise that made laugh!! GL all, when she moves, she moves :) MCAP now at £28m, close to peers with similar products, but still a long way to go!

When are shareholders Q&As published? Normally around this date monthly isnt it?

Absolute carnage on the stock markets this morning / early afternoon, however we are blue :) Agree with the comments, if the results were not as expected why would Suze expose herself like that? Should be tapping on 30s door alone on that update :)

Think its important to look at MCAP 56m / Shares in issue 25m, just doing a tiny bit of research looks like they are in bed with Roche with the SARS-CoV-2 testing portfolio. Not invested there but will be good to monitor the appetite and SP rise over there :)

Let them sell, try buying in on release of possible good news, it goes straight into auction and try placing your trade in that frenzy as you get the ask which is determined. With a low amount of share in issue, try guessing that entry SP point? :)

Matthew Cheeks - Director of Biopharmaceutical Development at AZ is the fella your are looking for who liked Suzys post :)

That made me laugh Borgie!! :) share manipulation at its finest yesterday searching for stop losses! I don’t think the drop was manufactured for Hargreaves though, could expect some large TR3s after hours tomorrow evening?

Wonder if there is any connection with Mark Lynch as he’s leading the investigation on 201 is he not?

Called that pretty early WS, it’s only Wednesday:)

Which is why tomorrow I think will be a rise as the usual FOMO sets in :)

Thanks grace, so with 8 being the optimum do we know how many of the 12 patients enrolled are on 8?