Member Info for Titania

https://www.news-medical.net/news/20220405/Direction-and-magnitude-of-predictors-of-all-cause-mortality-following-hospitalization-with-influenza-RSV-or-SARS-CoV-2.aspx

He must be looking forward to topping up his ISA at 22p

Still smiling!

I don't think Synairgen would sign up for such an eminent forum without some pointers gleaned from the deep data dive enabling them to demonstrate the robustness of the 36% effect.

Powerful for us to have the data to show how SNG interacts with steroids. If we can show that administering SNG with steroids drops the statistical significance from 95% to approx 90% then that might be better than having no data to show SNG's interaction in the steroid landscape. The RNS does not seem to preclude another announcement on the deep dive data before the conference.

What has Stephen Barry - A Magician got to do with it?

The post before the one deleted said she had a busy Friday with 10 interviews. New tweet talks of busy week with 50 interviews! So 10 a day for five days?

https://www.medicalnewstoday.com/articles/could-cancer-therapies-be-used-to-treat-tb

Could SNG potentially treat cancer and TB as well?

https://www.forbes.com/sites/williamhaseltine/2022/04/01/the-artful-dodger-sars-cov-2-evading-immunity-by-inhibition-of-interferon/

Interferon B the most potent of all the interferons.

Apologies if already posted.

https://news.yale.edu/2022/03/30/insights-outcomes-t-cells-drinking-risks-and-covid-19s-road-ahead

Buy in the US and housekeeping here?

https://www.bloomberg.com/quote/SYGGF:US

"We have demonstrated that a critical role of type I interferon is protecting patients from a severe disease, hospitalization, and death. Given a well-established protective role of type I interferons against a broad range of viral infections, this study suggests that type I interferons can serve as an important therapeutic agent where virus-specific pharmacological approaches are not available. This can provide an essential therapeutic application for novel emerging viruses that are not well-characterized, and the development of target therapies can take years to come."

What an amazing man Mario Castro is -

https://www.lung.org/about-us/our-leadership/mario-castro

And one of his American lung association researchers looking at type 1 interferons -

https://www.lung.org/research/about-our-research/meet-the-researchers/lokesh-sharma

From 17-20 mins. Dr Castro talks about Meta Analysis and assessment of each sub trial and then removal of poorly done studies before combination. Apologies if already seen.

https://www.youtube.com/watch?v=b-S1M7MANYs

https://www.pharmaceutical-technology.com/news/fda-gsk-vir-sotrovimab-use/

Apologies if already posted:-

"The CRF is also recruiting patients to the national AGILE COVID-19 drug testing platform, which aims to fast-track potential new COVID-19 treatments through early phase clinical trials to help find drugs which can prevent people who contract the virus from becoming severely ill."
Professor Christopher Edwards, Associate Director of the Southampton CRF and Principal Investigator for AGILE in Southampton, said:
“Despite the huge success of the NHS COVID-19 vaccination programme, we still need to find treatments for people who do contract the virus to prevent them developing more serious disease and reduce hospital admissions.
"The CRF has been involved in many COVID-19 trials and we have experience with early phase studies, so we are delighted to be recruiting patients to the AGILE platform here in Southampton."

https://www.southampton.ac.uk/ctu/news/2022/03/17-pioneering-clinical-research-facility-receives-fundinng-boost.page

https://www.dailyecho.co.uk/news/19975486.nihr-southampton-clinical-research-facility-get-10m-boost/

During the last 10 years, more than 800 clinical trials have been completed in the city, overing a range of conditions including many types of cancer, asthma, chronic obstructive pulmonary disease (COPD), infection and inflammation, musculoskeletal and neurological conditions in both adults and children.

Southampton has also been a crucial partner in the nationwide Covid-19 response, delivering the highest number of Covid-19 studies across all acute NHS trusts.

https://www.vox.com/2016/3/15/11225162/p-value-simple-definition-hacking

"Although the product still faces a long route to market and will probably need a large pharmaceutical company as a partner, if successful it has the potential to corner a slice of a multi-billion-pound global market."

https://www.dailyecho.co.uk/business/4729716.vital-step-forward-in-battle-with-swine-flu/